[←][→] mmu  Insig1 Gene
functional annotation
Function   insulin induced gene 1  
GO BP
GO:0036316 [list] [network] SREBP-SCAP complex retention in endoplasmic reticulum  (2 genes)  IBA ISO  
GO:1901303 [list] [network] negative regulation of cargo loading into COPII-coated vesicle  (2 genes)  ISO  
GO:0060363 [list] [network] cranial suture morphogenesis  (8 genes)  IGI  
GO:0032933 [list] [network] SREBP signaling pathway  (10 genes)  IBA ISO  
GO:0070862 [list] [network] negative regulation of protein exit from endoplasmic reticulum  (10 genes)  ISO  
GO:0006991 [list] [network] response to sterol depletion  (12 genes)  IDA  
GO:0045717 [list] [network] negative regulation of fatty acid biosynthetic process  (16 genes)  IGI  
GO:0042474 [list] [network] middle ear morphogenesis  (24 genes)  IGI  
GO:0010894 [list] [network] negative regulation of steroid biosynthetic process  (25 genes)  IGI  
GO:0036315 [list] [network] cellular response to sterol  (25 genes)  ISO  
GO:0006695 [list] [network] cholesterol biosynthetic process  (40 genes)  IBA IGI ISO  
GO:0016126 [list] [network] sterol biosynthetic process  (46 genes)  IBA IGI  
GO:0045599 [list] [network] negative regulation of fat cell differentiation  (58 genes)  IDA  
GO:0006641 [list] [network] triglyceride metabolic process  (72 genes)  IGI  
GO:0042632 [list] [network] cholesterol homeostasis  (96 genes)  ISO  
GO:0060021 [list] [network] roof of mouth development  (101 genes)  IGI  
GO:0042472 [list] [network] inner ear morphogenesis  (118 genes)  IGI  
GO:0008203 [list] [network] cholesterol metabolic process  (126 genes)  IGI  
GO:0032869 [list] [network] cellular response to insulin stimulus  (138 genes)  IBA  
GO:0008202 [list] [network] steroid metabolic process  (264 genes)  IEA  
GO:0006629 [list] [network] lipid metabolic process  (1148 genes)  IEA  
GO CC
GO:0032937 [list] [network] SREBP-SCAP-Insig complex  (3 genes)  IBA ISO  
GO:0005783 [list] [network] endoplasmic reticulum  (1825 genes)  IBA ISO TAS  
GO:0016021 [list] [network] integral component of membrane  (5954 genes)  IEA  
GO:0016020 [list] [network] membrane  (9571 genes)  IEA  
GO MF
GO:0008142 [list] [network] oxysterol binding  (5 genes)  ISO  
GO:0008289 [list] [network] lipid binding  (819 genes)  IEA  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG
Protein NP_705746.1 
BLAST NP_705746.1 
Orthologous [Ortholog page] INSIG1 (hsa)  INSIG2 (hsa)  Insig1 (rno)  Insig2 (mmu)  Insig2 (rno)  insig1 (dre)  insig2 (dre)  INSIG1 (gga)  INSIG2 (gga)  INSIG1 (cfa)  INSIG2 (cfa)  INSIG2 (mcc)  INSIG1 (mcc)  INSIG2 (fca)  INSIG1 (fca)  LOC120102490 (rno) 
Subcellular
localization
wolf
plas 9  (predict for NP_705746.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu00100 Steroid biosynthesis 10
mmu00900 Terpenoid backbone biosynthesis 5
mmu04913 Ovarian steroidogenesis 2
mmu04976 Bile secretion 2
mmu00280 Valine, leucine and isoleucine degradation 2
Genes directly connected with Insig1 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
18.2 Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 [detail] 6 208715
18.0 Cyp51 cytochrome P450, family 51 [detail] 3 13121
17.0 Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase [detail] 22 15357
6.7 Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 [detail] 0 382051
5.5 Sephs2 selenophosphate synthetase 2 [detail] 0 20768
Coexpressed
gene list		 [Coexpressed gene list for Insig1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 231070      
Refseq ID (protein) NP_705746.1 


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