Publication for Cyp51 and Insig1

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Cyp51 cytochrome P450, family 51 13121 [link]
mmu Insig1 insulin induced gene 1 231070

Pubmed ID Priority Text
27977712 0.95 Cyp51; fold change, 5.6), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Hmgcr; fold change, 2.5), hydroxysteroid (17-beta) dehydrogenase 7 (Hsd17b7; fold change, 2.8), insulin induced gene 1 (Insig1; fold change, 1.8), sterol-C4-methyl oxidase-like (Sc4mol; fold change, 4.5), and leptin receptor (Lepr; fold change, 1.6) were upregulated.
0.81 Cyp51, Hmgcr, and Insig1) and fatty acid beta-oxidation (Acsl3), whereas it significantly downregulated expression of genes related to fatty acid biosynthesis (Scd1, Acot11, and Mlxipl/carbohydrate responsive element-binding protein [ChREBP]), triacylglycerol biosynthesis (Mogat1), oxidative stress (growth differentiation factor 15, Gdf15), inflammatory and immune processes (Cfd, Chi3l1, Ctse, Orm2, Rorc, and Tlr5), ceramide biosynthesis (Sptlc3), and lipid storage (Plin4).
19691840 0.95 Insig1 and Sqle while expression of Cyp51a1 and Srebp2 remained unchanged.
24486573 0.81 CYP51 (I), and INSIG1 (J) with a trend towards such an effect for INSIG2A (K) also.



The preparation time of this page was 0.0 [sec].