[←][→] mmu  Hspd1 Gene
functional annotation
Function   heat shock protein 1 (chaperonin)  
GO BP
GO:0048291 [list] [network] isotype switching to IgG isotypes  (1 genes)  ISO  
GO:0034514 [list] [network] mitochondrial unfolded protein response  (2 genes)  IBA  
GO:0045041 [list] [network] protein import into mitochondrial intermembrane space  (4 genes)  IBA  
GO:0002842 [list] [network] positive regulation of T cell mediated immune response to tumor cell  (5 genes)  ISO  
GO:0071866 [list] [network] negative regulation of apoptotic process in bone marrow cell  (6 genes)  ISO  
GO:0042026 [list] [network] protein refolding  (15 genes)  ISO  
GO:0044406 [list] [network] adhesion of symbiont to host  (15 genes)  IDA  
GO:0002755 [list] [network] MyD88-dependent toll-like receptor signaling pathway  (16 genes)  ISO  
GO:0098761 [list] [network] cellular response to interleukin-7  (17 genes)  IDA  
GO:1903427 [list] [network] negative regulation of reactive oxygen species biosynthetic process  (22 genes)  ISO  
GO:0032727 [list] [network] positive regulation of interferon-alpha production  (24 genes)  IBA IDA ISO  
GO:0043032 [list] [network] positive regulation of macrophage activation  (30 genes)  ISO  
GO:0032733 [list] [network] positive regulation of interleukin-10 production  (41 genes)  ISO  
GO:0032735 [list] [network] positive regulation of interleukin-12 production  (43 genes)  ISO  
GO:0042100 [list] [network] B cell proliferation  (50 genes)  ISO  
GO:0008637 [list] [network] apoptotic mitochondrial changes  (67 genes)  IBA ISO  
GO:0006919 [list] [network] activation of cysteine-type endopeptidase activity involved in apoptotic process  (81 genes)  ISO  
GO:0032729 [list] [network] positive regulation of interferon-gamma production  (84 genes)  IBA IDA IGI ISO  
GO:0006986 [list] [network] response to unfolded protein  (101 genes)  ISO  
GO:0032755 [list] [network] positive regulation of interleukin-6 production  (108 genes)  IBA ISO  
GO:0032760 [list] [network] positive regulation of tumor necrosis factor production  (109 genes)  ISO  
GO:0051702 [list] [network] biological process involved in interaction with symbiont  (113 genes)  ISO  
GO:0050729 [list] [network] positive regulation of inflammatory response  (133 genes)  ISO  
GO:0006457 [list] [network] protein folding  (156 genes)  IBA  
GO:0043524 [list] [network] negative regulation of neuron apoptotic process  (186 genes)  ISO  
GO:0050821 [list] [network] protein stabilization  (188 genes)  ISO  
GO:0042113 [list] [network] B cell activation  (196 genes)  ISO  
GO:0050870 [list] [network] positive regulation of T cell activation  (221 genes)  IBA IDA ISO  
GO:0042110 [list] [network] T cell activation  (295 genes)  IBA IDA IGI ISO  
GO:0043065 [list] [network] positive regulation of apoptotic process  (598 genes)  ISO  
GO:0043066 [list] [network] negative regulation of apoptotic process  (968 genes)  ISO  
GO CC
GO:0046696 [list] [network] lipopolysaccharide receptor complex  (6 genes)  ISO  
GO:0030061 [list] [network] mitochondrial crista  (14 genes)  ISO  
GO:0042588 [list] [network] zymogen granule  (25 genes)  ISO  
GO:0005782 [list] [network] peroxisomal matrix  (26 genes)  ISO  
GO:0031985 [list] [network] Golgi cisterna  (61 genes)  ISO  
GO:0005905 [list] [network] clathrin-coated pit  (70 genes)  ISO  
GO:0005791 [list] [network] rough endoplasmic reticulum  (89 genes)  ISO  
GO:0070062 [list] [network] extracellular exosome  (104 genes)  ISO  
GO:0030135 [list] [network] coated vesicle  (195 genes)  ISO  
GO:0043209 [list] [network] myelin sheath  (215 genes)  HDA  
GO:0005759 [list] [network] mitochondrial matrix  (276 genes)  IBA ISO  
GO:0005769 [list] [network] early endosome  (322 genes)  ISO  
GO:0045121 [list] [network] membrane raft  (390 genes)  ISO  
GO:0030141 [list] [network] secretory granule  (431 genes)  IDA ISO  
GO:0005743 [list] [network] mitochondrial inner membrane  (454 genes)  HDA IBA ISO  
GO:0009986 [list] [network] cell surface  (1142 genes)  ISO  
GO:0005794 [list] [network] Golgi apparatus  (1525 genes)  ISO  
GO:0005739 [list] [network] mitochondrion  (1890 genes)  HDA IDA ISO  
GO:0005615 [list] [network] extracellular space  (2015 genes)  ISO  
GO:0005829 [list] [network] cytosol  (3785 genes)  ISO  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  IDA ISO  
GO:0032991 [list] [network] protein-containing complex  (5540 genes)  ISO  
GO:0016020 [list] [network] membrane  (9571 genes)  IMP  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  IDA ISO  
GO:0043231 [list] [network] intracellular membrane-bounded organelle  (11551 genes)  IDA  
GO MF
GO:0034186 [list] [network] apolipoprotein A-I binding  (5 genes)  ISO  
GO:0008035 [list] [network] high-density lipoprotein particle binding  (10 genes)  ISO  
GO:0034185 [list] [network] apolipoprotein binding  (18 genes)  ISO  
GO:0001530 [list] [network] lipopolysaccharide binding  (35 genes)  IDA ISO  
GO:0002039 [list] [network] p53 binding  (76 genes)  ISO  
GO:0003725 [list] [network] double-stranded RNA binding  (89 genes)  ISO  
GO:0051087 [list] [network] chaperone binding  (107 genes)  IBA ISO  
GO:0016853 [list] [network] isomerase activity  (175 genes)  IEA  
GO:0140030 [list] [network] modification-dependent protein binding  (202 genes)  ISO  
GO:0016887 [list] [network] ATP hydrolysis activity  (248 genes)  IEA  
GO:0031625 [list] [network] ubiquitin protein ligase binding  (316 genes)  ISO  
GO:0005524 [list] [network] ATP binding  (1396 genes)  IEA  
GO:0044877 [list] [network] protein-containing complex binding  (1549 genes)  ISO  
GO:0000166 [list] [network] nucleotide binding  (2052 genes)  IEA  
GO:0019899 [list] [network] enzyme binding  (2298 genes)  ISO  
KEGG mmu03018 [list] [network] RNA degradation (84 genes)
mmu04940 [list] [network] Type I diabetes mellitus (70 genes)
mmu05134 [list] [network] Legionellosis (61 genes)
mmu05152 [list] [network] Tuberculosis (180 genes)
mmu05417 [list] [network] Lipid and atherosclerosis (216 genes)
Protein NP_001343441.1  NP_034607.3 
BLAST NP_001343441.1  NP_034607.3 
Orthologous [Ortholog page] HSPD1 (hsa)  Hsp60A (dme)  Hsp60C (dme)  Hsp60B (dme)  Hspd1 (rno)  hsp-60 (cel)  hspd1 (dre)  HSPD1 (gga)  HSPD1 (cfa)  LOC693438 (mcc)  HSPD1 (mcc)  HSP60 (sce)  HSPD1 (fca)  LOC103694176 (rno) 
Subcellular
localization
wolf
mito 9  (predict for NP_001343441.1)
mito 9  (predict for NP_034607.3)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu03018 RNA degradation 2
mmu05152 Tuberculosis 2
mmu05417 Lipid and atherosclerosis 2
mmu04932 Non-alcoholic fatty liver disease 2
mmu05010 Alzheimer disease 2
Genes directly connected with Hspd1 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
15.1 Hspe1 heat shock protein 1 (chaperonin 10) [detail] 50 15528
11.9 Hspa9 heat shock protein 9 [detail] 34 15526
11.7 Cct6a chaperonin containing Tcp1, subunit 6a (zeta) [detail] 0 12466
9.9 Lrpprc leucine-rich PPR-motif containing [detail] 1 72416
Coexpressed
gene list		 [Coexpressed gene list for Hspd1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 15510      
Refseq ID (protein) NP_001343441.1 
NP_034607.3 


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