Publication for Cdk1 and Top2a

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Cdk1	cyclin-dependent kinase 1	12534			[link]
mmu	Top2a	topoisomerase (DNA) II alpha	21973

Pubmed ID	Priority	Text
30849121	0.98	Top2a, Ccnb2 and Cdk1) with expression levels superior to 20-fold in beta cells from HFD mice compared to controls.
	0.91	Top2a, Ccnb2 and Cdk1.
18942075	0.98	Cdc2a, Cenpa, Gmnn, Mad2l1, Mcm5, Mki67, Odc, Plk1, Tk1, Top2a, Ung, and Tpx2 (Fig. 5A,B), and suggest that v-rasHa cannot abrogate the TGFbeta1 cell cycle arrest program.
22363607	0.98	Cdk1, Cyclins A2, B1, B2, D2, D3, E1, E2 and other genes involved cell cycle progression (Aurka (aurora kinase A), Aurkb, Cdc6, Cdc7, Cdc20 and Cdc25b), and transcripts involved in DNA synthesis and replication (Rrm2 (ribonucleotide reductase M2), Lig1 (ligase 1) and Top2a (DNA topoisomerase II alpha)) were enriched in the fetal liver.
22860109	0.98	Cdk1, Cep55, Cks2, Mcm5, Mki67, Smc2, Top2a, and Ube2c are all up-regulated in 7EX.
26828310	0.98	TOP2A, CDK1, PLK4, and CENP (Figure 1D).
28820341	0.98	CDK1 and TOP2A transcripts associated with the S/G2/M phases of the cell cycle (Fig. 6F).
29672594	0.98	Cdk1, and Top2a), cyclins and cell cycle regulation pathway (genes involved: Ccnb2, Ccne2, Cdk1, and E2f1) are enriched positively in IFNARfl/fl x Foxp3YFP-Cre Tregs compared to Tregs from Foxp3YFP-Cre mice, suggesting that cell cycle genes are more functional in Treg-specific IFNAR deficient mice.
30271991	0.98	Cdk1, Top2a) were all consistently upregulated during S/G2/M in all mammary epithelial populations (basal, HR- luminal, HR+ luminal).
30500539	0.98	Cdk1, Top2a and Cenpm (Figure 4D, S4A).
30604742	0.98	Top2a, Mki67, and Cdk1), multiple histone cluster 1 genes and Hells, a gene encoding a lymphoid-specific helicase involved in "lymphocyte proliferation".
28901457	0.97	TOP2A and CDK1 were associated with tumor grade, hepatitis virus infection status, satellites and vascular invasion (Fig. 6A-H).
	0.97	TOP2A and CDK1 were associated with tumor grade, hepatitis virus infection status, satellites and vascular invasion, indicating vital roles of TOP2A and CDK1 in the carcinogenesis or progression of HCC.
	0.88	TOP2A and CDK1 and tumor grade, hepatitis virus infection status, satellites and vascular invasion in the Wurmbach Liver dataset. (A-D) TOP2A mRNA expression in HCC compared to normal liver tissues.
28099942	0.97	CDK1 (cyclin-dependent kinase 1), PRC1 (Protein Regulator of Cytokinesis 1) and TOP2A (topoisomerase II alpha) were rapidly overexpressed at the age of 2 and 3 months in mice retina developing Rb, but never as high as in SV40-TAg/Bigh3-/- mice (Figure 2D).
	0.95	CDK1 and TOP2A RNA around 10 fold in SV40-TAg, while all three markers were increased 100 fold in the SV40-TAg/Bigh3-/- retina when compared to wild-type retina of the same age.
32157166	0.97	cdk1 and top2a mRNA expression did not differ among all groups, suggesting that most cells arrested in the G1 phase.
	0.89	cdk1 and top2a.
23936388	0.97	top2a, Hist1h2ad, Hist1h2ah, cdk1, Kif 23, pbk, anln and prc1 were significantly up-regulated.
27811056	0.97	Top2a, Mki67 and Cdk1.
28472656	0.97	Cdk1, Top2a, Fgf15, Ube2c, Uhrf1, and Ascl1) were associated with developmentally downregulated super-enhancers (Fig. 4C) while several rod genes (e.g., Pde6a, Guca1b, Guca1a, Nr2e3, Rbp3, and Crx) were associated with developmentally upregulated super-enhancers (Fig. 4D).
30038716	0.97	TOP2A, p-AURKB, p-CDC2, p-CDC20 and induce p21 in breast tumors derived from mice.
31444334	0.97	Top2a, Cdk1, Mki67, and Cenpa (Supplementary Fig. 2D), suggesting that subpopulation of tumor cells conferred tolerance to treatment or adapted to drug selection.
31746348	0.96	TOP2A, CDK1, IL8, KIAA0101, CCNB1, BIRC5, STAT3, TYMS, UBE2C, ABCA12, TMPRSS11D and S100A9 may all play a pivotal role in the molecular mechanisms underlying psoriasis.
26051537	0.94	Cdk1, Cdca3, Pbk, Dct, Serinc5, 9630013A20Rik, Top2A, and Cdca5), three of which (Bfsp2, Serinc5, and Opalin) map to both oligodendrocytes and their progenitors.
32248062	0.93	Top2a, and Cdk1.