KEGG 05031 Amphetamine addiction
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05031 Amphetamine addiction 21
hsa04728 Dopaminergic synapse 18
hsa04024 cAMP signaling pathway 16
hsa04713 Circadian entrainment 14
hsa05022 Pathways of neurodegeneration - multiple diseases 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu05031 Amphetamine addiction 20
mmu04024 cAMP signaling pathway 14
mmu05022 Pathways of neurodegeneration - multiple diseases 14
mmu04728 Dopaminergic synapse 13
mmu05034 Alcoholism 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05031 Amphetamine addiction 29
rno04728 Dopaminergic synapse 21
rno05034 Alcoholism 18
rno04024 cAMP signaling pathway 17
rno04720 Long-term potentiation 15
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05031 Amphetamine addiction 13
mcc04024 cAMP signaling pathway 11
mcc04728 Dopaminergic synapse 10
mcc04713 Circadian entrainment 9
mcc04921 Oxytocin signaling pathway 9
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa05031 Amphetamine addiction 12
cfa04728 Dopaminergic synapse 8
cfa04921 Oxytocin signaling pathway 8
cfa05200 Pathways in cancer 8
cfa05163 Human cytomegalovirus infection 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca05031 Amphetamine addiction 14
fca05022 Pathways of neurodegeneration - multiple diseases 10
fca04921 Oxytocin signaling pathway 9
fca05417 Lipid and atherosclerosis 9
fca04024 cAMP signaling pathway 8
Gene list in the network
Symbol Function*
ATF3 activating transcription factor 3
CACNA1C calcium voltage-gated channel subunit alpha1 C
CALM2 calmodulin 2
CALML3 calmodulin like 3
CAMK2B calcium/calmodulin dependent protein kinase II beta
CREB1 cAMP responsive element binding protein 1
ATF2 activating transcription factor 2
DRD1 dopamine receptor D1
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
FOS Fos proto-oncogene, AP-1 transcription factor subunit
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
GRIA1 glutamate ionotropic receptor AMPA type subunit 1
GRIA2 glutamate ionotropic receptor AMPA type subunit 2
GRIA4 glutamate ionotropic receptor AMPA type subunit 4
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C glutamate ionotropic receptor NMDA type subunit 2C
JUN Jun proto-oncogene, AP-1 transcription factor subunit
JUND JunD proto-oncogene, AP-1 transcription factor subunit
KCND3 potassium voltage-gated channel subfamily D member 3
MAOA monoamine oxidase A
MAOB monoamine oxidase B
NR4A2 nuclear receptor subfamily 4 group A member 2
PPP3R1 protein phosphatase 3 regulatory subunit B, alpha
RYR2 ryanodine receptor 2
SCN1A sodium voltage-gated channel alpha subunit 1
TH tyrosine hydroxylase
KLF4 Kruppel like factor 4
ACTR2 actin related protein 2
SF3B1 splicing factor 3b subunit 1
PPP1R15A protein phosphatase 1 regulatory subunit 15A
CALML5 calmodulin like 5
COL20A1 collagen type XX alpha 1 chain
TMEM132B transmembrane protein 132B
MIR23AHG miR-23a/27a/24-2 cluster host gene
Symbol Function*
Arc activity regulated cytoskeletal-associated protein
Atf3 activating transcription factor 3
Calm1 calmodulin 1
Calm2 calmodulin 2
Calm3 calmodulin 3
Camk2g calcium/calmodulin-dependent protein kinase II gamma
Drd1 dopamine receptor D1
Egr1 early growth response 1
Fos FBJ osteosarcoma oncogene
Fosb FBJ osteosarcoma oncogene B
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2)
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1)
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3)
Nr4a1 nuclear receptor subfamily 4, group A, member 1
Jun jun proto-oncogene
Klf4 Kruppel-like factor 4 (gut)
Maoa monoamine oxidase A
Pdyn prodynorphin
Dusp1 dual specificity phosphatase 1
Stx1a syntaxin 1A (brain)
Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3)
Calml3 calmodulin-like 3
Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1
Calm4 calmodulin 4
Grm5 glutamate receptor, metabotropic 5
Maob monoamine oxidase B
Gpr6 G protein-coupled receptor 6
Tmem63c transmembrane protein 63c
Gm94 predicted gene 94
Adgrl1 adhesion G protein-coupled receptor L1
Symbol Function*
Cacna1c calcium voltage-gated channel subunit alpha1 C
Calm1 calmodulin 1
Calm3 calmodulin 3
Drd1 dopamine receptor D1
Egr1 early growth response 1
Grin2a glutamate ionotropic receptor NMDA type subunit 2A
Grin2b glutamate ionotropic receptor NMDA type subunit 2B
Jun Jun proto-oncogene, AP-1 transcription factor subunit
Ppp1cc protein phosphatase 1 catalytic subunit gamma
Ppp3ca protein phosphatase 3 catalytic subunit alpha
Ppp3cb protein phosphatase 3 catalytic subunit beta
Slc6a3 solute carrier family 6 member 3
Prkcb protein kinase C, beta
Camk4 calcium/calmodulin-dependent protein kinase IV
Egr4 early growth response 4
Atf3 activating transcription factor 3
Camk2a calcium/calmodulin-dependent protein kinase II alpha
Slc18a2 solute carrier family 18 member A2
Ppp1cb protein phosphatase 1 catalytic subunit beta
Maob monoamine oxidase B
Cntn6 contactin 6
Pdyn prodynorphin
Maoa monoamine oxidase A
Rasgrp1 RAS guanyl releasing protein 1
Gria4 glutamate ionotropic receptor AMPA type subunit 4
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Gria1 glutamate ionotropic receptor AMPA type subunit 1
Calm2 calmodulin 2
Arc activity-regulated cytoskeleton-associated protein
Adcy5 adenylate cyclase 5
Nr4a1 nuclear receptor subfamily 4, group A, member 1
Gpr6 G protein-coupled receptor 6
Kalrn kalirin, RhoGEF kinase
Hdac2 histone deacetylase 2
Egr2 early growth response 2
Grin3a glutamate ionotropic receptor NMDA type subunit 3A
Fos Fos proto-oncogene, AP-1 transcription factor subunit
Capza2 capping actin protein of muscle Z-line subunit alpha 2
Ier2 immediate early response 2
Fosb FosB proto-oncogene, AP-1 transcription factor subunit
Symbol Function*
CX3CL1 C-X3-C motif chemokine ligand 1
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
FOS Fos proto-oncogene, AP-1 transcription factor subunit
ARC activity regulated cytoskeleton associated protein
DUSP1 dual specificity phosphatase 1
CCDC184 coiled-coil domain containing 184
CAMK2B calcium/calmodulin dependent protein kinase II beta
PTCHD4 patched domain containing 4
CAMK2A calcium/calmodulin dependent protein kinase II alpha
KLF6 Kruppel like factor 6
ID1 inhibitor of DNA binding 1, HLH protein
EGR4 early growth response 4
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
JUN Jun proto-oncogene, AP-1 transcription factor subunit
CALM3 calmodulin 3
REEP2 receptor accessory protein 2
EGR1 early growth response 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
CACNA1C calcium voltage-gated channel subunit alpha1 C
PPP1CA protein phosphatase 1 catalytic subunit alpha
CTDNEP1 CTD nuclear envelope phosphatase 1
CFL1 cofilin 1
ZFP36 ZFP36 ring finger protein
LOC100424766 uncharacterized LOC100424766
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
IQCN IQ motif containing N
Symbol Function*
PPP3CA protein phosphatase 3 catalytic subunit alpha
PRKACA protein kinase cAMP-activated catalytic subunit alpha
GNAS GNAS complex locus
HDAC2 histone deacetylase 2
EGR2 early growth response 2
EGR1 early growth response 1
KLF4 Kruppel like factor 4
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
FKBP8 FKBP prolyl isomerase 8
CALML5 calmodulin like 5
FOS Fos proto-oncogene, AP-1 transcription factor subunit
PRKCA protein kinase C alpha
CREB3L2 cAMP responsive element binding protein 3 like 2
JUN Jun proto-oncogene, AP-1 transcription factor subunit
ERN1 endoplasmic reticulum to nucleus signaling 1
MARCKS myristoylated alanine rich protein kinase C substrate
C18H11orf24 chromosome 18 C11orf24 homolog
JUNB JunB proto-oncogene, AP-1 transcription factor subunit
LOC102153034 calmodulin-like protein 3
OTUD1 OTU deubiquitinase 1
ARC activity regulated cytoskeleton associated protein
Symbol Function*
FOS Fos proto-oncogene, AP-1 transcription factor subunit
GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2
GRIN1 glutamate ionotropic receptor NMDA type subunit 1
CAMK2A calcium/calmodulin dependent protein kinase II alpha
PDYN prodynorphin
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
PPP3CB protein phosphatase 3 catalytic subunit beta
GRIA4 glutamate ionotropic receptor AMPA type subunit 4
TRIM72 tripartite motif containing 72
EGR1 early growth response 1
PPP3R1 protein phosphatase 3 regulatory subunit B, alpha
LOC101091541 phosphatidylinositol phosphatase PTPRQ
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
PPP3CA protein phosphatase 3 catalytic subunit alpha
JUN Jun proto-oncogene, AP-1 transcription factor subunit
CAMK2B calcium/calmodulin dependent protein kinase II beta
CALML4 calmodulin like 4
ARC activity regulated cytoskeleton associated protein
LOC111556187 calmodulin-like protein 4
LOC111558349 uncharacterized LOC111558349


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