KEGG 04213 Longevity regulating pathway - multiple species
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) dme(Fly) cel(Nematoda) mcc(Monkey) cfa(Dog) sce(Budding yeast) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04213 Longevity regulating pathway - multiple species 9
hsa04010 MAPK signaling pathway 7
hsa04141 Protein processing in endoplasmic reticulum 6
hsa04144 Endocytosis 6
hsa03040 Spliceosome 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04213 Longevity regulating pathway - multiple species 17
mmu04211 Longevity regulating pathway 12
mmu04152 AMPK signaling pathway 11
mmu04915 Estrogen signaling pathway 10
mmu04010 MAPK signaling pathway 10
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04213 Longevity regulating pathway - multiple species 17
rno04211 Longevity regulating pathway 11
rno04915 Estrogen signaling pathway 9
rno04910 Insulin signaling pathway 9
rno04010 MAPK signaling pathway 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme04213 Longevity regulating pathway - multiple species 20
dme04140 Autophagy - animal 9
dme04068 FoxO signaling pathway 9
dme04150 mTOR signaling pathway 8
dme00230 Purine metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel04213 Longevity regulating pathway - multiple species 17
cel04068 FoxO signaling pathway 8
cel04140 Autophagy - animal 8
cel04150 mTOR signaling pathway 8
cel04212 Longevity regulating pathway - worm 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04213 Longevity regulating pathway - multiple species 15
mcc04211 Longevity regulating pathway 9
mcc04010 MAPK signaling pathway 9
mcc04152 AMPK signaling pathway 8
mcc04915 Estrogen signaling pathway 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04213 Longevity regulating pathway - multiple species 14
cfa04211 Longevity regulating pathway 9
cfa05200 Pathways in cancer 8
cfa04010 MAPK signaling pathway 8
cfa04915 Estrogen signaling pathway 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sce04213 Longevity regulating pathway - multiple species 21
sce04141 Protein processing in endoplasmic reticulum 9
sce04138 Autophagy - yeast 7
sce04113 Meiosis - yeast 6
sce03040 Spliceosome 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04213 Longevity regulating pathway - multiple species 14
fca04211 Longevity regulating pathway 13
fca04923 Regulation of lipolysis in adipocytes 10
fca04935 Growth hormone synthesis, secretion and action 10
fca04022 cGMP-PKG signaling pathway 8
Gene list in the network
Symbol Function*
FOXO1 forkhead box O1
FOXO3 forkhead box O3
HSPA1A heat shock protein family A (Hsp70) member 1A
HSPA1B heat shock protein family A (Hsp70) member 1B
HSPA1L heat shock protein family A (Hsp70) member 1 like
HSPA2 heat shock protein family A (Hsp70) member 2
HSPA6 heat shock protein family A (Hsp70) member 6
HSPB1 heat shock protein family B (small) member 1
DNAJB1 DnaJ heat shock protein family (Hsp40) member B1
IGF1R insulin like growth factor 1 receptor
IRS2 insulin receptor substrate 2
DNAJB4 DnaJ heat shock protein family (Hsp40) member B4
C17orf67 chromosome 17 open reading frame 67
IRAIN IGF1R antisense imprinted non-protein coding RNA
Symbol Function*
Adcy7 adenylate cyclase 7
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Cryab crystallin, alpha B
Eef2k eukaryotic elongation factor-2 kinase
Hras Harvey rat sarcoma virus oncogene
Hspa8 heat shock protein 8
Hsph1 heat shock 105kDa/110kDa protein 1
Hspb1 heat shock protein 1
Hspa1b heat shock protein 1B
Hspa2 heat shock protein 2
Ins1 insulin I
Ins2 insulin II
Mbd3 methyl-CpG binding domain protein 3
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
Prkag1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Try4 trypsin 4
Trpv2 transient receptor potential cation channel, subfamily V, member 2
Bag3 BCL2-associated athanogene 3
Mtch1 mitochondrial carrier 1
Foxo3 forkhead box O3
Akt1s1 AKT1 substrate 1 (proline-rich)
Dnajb1 DnaJ heat shock protein family (Hsp40) member B1
Csnk1g2 casein kinase 1, gamma 2
Hspa1a heat shock protein 1A
Symbol Function*
Hspb1 heat shock protein family B (small) member 1
Hspa1a heat shock protein family A (Hsp70) member 1A
Insr insulin receptor
Hspa1l heat shock protein family A (Hsp70) member 1 like
Cryab crystallin, alpha B
Irs1 insulin receptor substrate 1
Nrdc nardilysin convertase
Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Mtor mechanistic target of rapamycin kinase
Hspa2 heat shock protein family A (Hsp70) member 2
Adcy3 adenylate cyclase 3
Clpb caseinolytic mitochondrial matrix peptidase chaperone subunit B
Foxo1 forkhead box O1
Rptor regulatory associated protein of MTOR, complex 1
Hras HRas proto-oncogene, GTPase
Foxo3 forkhead box O3
Mlf2 myeloid leukemia factor 2
Dnajb1 DnaJ heat shock protein family (Hsp40) member B1
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Klf13 Kruppel-like factor 13
Hspa1b heat shock protein family A (Hsp70) member 1B
Symbol Function*
Atg5 Autophagy-related 5
GstT4 Glutathione S transferase T4
Thor thor
ACXC Adenylyl cyclase X C
Sirt1 Sirtuin 1
CG32301 uncharacterized protein
DnaJ-1 DnaJ-like-1
S6k Ribosomal protein S6 kinase
Ilp2 Insulin-like peptide 2
Ilp3 Insulin-like peptide 3
stv starvin
Cat Catalase
Ras85D Ras oncogene at 85D
Csk C-terminal Src kinase
Akt1 Akt1
Pi3K92E Phosphatidylinositol 3-kinase 92E
InR Insulin-like receptor
Hsp68 Heat shock protein 68
Hsp70Bb Heat-shock-protein-70Bb
Hsp70Bc Heat-shock-protein-70Bc
ACXB Adenylyl cyclase X B
ACXA Adenylyl cyclase X A
CG32305 uncharacterized protein
Ilp5 Insulin-like peptide 5
SIFa SIFamide
lncRNA:Hsromega Heat shock RNA omega
lncRNA:alphagamma-element:CR32865 alphagamma-element:CR32865
Symbol Function*
aap-1 phosphoinositide kinase AdAPter subunit
let-363 Target of rapamycin homolog
hsp-70 Heat Shock Protein
hda-3 Histone deacetylase
F44E5.4 Uncharacterized protein
F44E5.5 Uncharacterized protein
ctl-3 Catalase
daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;Receptor protein-tyrosine kinase
sip-1 Stress-induced protein 1
fkh-7 Fork-head domain-containing protein
daf-15 Raptor_N domain-containing protein
let-60 Ras protein let-60
let-92 Serine/threonine-protein phosphatase 2A catalytic subunit
hsp-16.2 Heat shock protein hsp-16.2;SHSP domain-containing protein
hsp-16.41 Heat shock protein Hsp-16.41
hsp-16.11 Heat shock protein Hsp-16.1/Hsp-16.11
hda-1 Histone deacetylase 1
ist-1 Insulin receptor SubsTrate homolog
akt-2 Serine/threonine-protein kinase akt-2
aak-2 5'-AMP-activated protein kinase catalytic subunit alpha-2
C14A11.5 Uncharacterized protein
aakg-4 AMP-Activated protein Kinase Gamma subunit
gap-3 GTPase Activating Protein family
aakg-1 AMP-Activated protein Kinase Gamma subunit
Symbol Function*
ATP6V0A1 ATPase H+ transporting V0 subunit a1
FOXP1 forkhead box P1
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2
FOXO1 forkhead box O1
DNAJA1 DnaJ heat shock protein family (Hsp40) member A1
INSR insulin receptor
HSPA8 heat shock protein family A (Hsp70) member 8
IGF1R insulin like growth factor 1 receptor
PRKACB protein kinase cAMP-activated catalytic subunit beta
BAG3 BAG cochaperone 3
HSPB1 heat shock protein family B (small) member 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
HSPA1L heat shock protein family A (Hsp70) member 1 like
DNAJB1 DnaJ heat shock protein family (Hsp40) member B1
AKT1S1 AKT1 substrate 1
HSPA6 heat shock protein family A (Hsp70) member 6
HSPA1A heat shock protein family A (Hsp70) member 1A
JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase
RPS6KB2 ribosomal protein S6 kinase B2
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
LOC114669856 heat shock 70 kDa protein 1
Symbol Function*
IL6ST interleukin 6 cytokine family signal transducer
PRKACA protein kinase cAMP-activated catalytic subunit alpha
HSP70 heat shock protein 70
NRAS NRAS proto-oncogene, GTPase
HSPB1 heat shock protein family B (small) member 1
IGF1R insulin like growth factor 1 receptor
LOC474850 heat shock 70 kDa protein 1-like
SEC63 SEC63 homolog, protein translocation regulator
HDAC2 histone deacetylase 2
CSDE1 cold shock domain containing E1
DNAJB1 DnaJ heat shock protein family (Hsp40) member B1
HSPH1 heat shock protein family H (Hsp110) member 1
PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1
HSPA8 heat shock protein family A (Hsp70) member 8
CRYAB crystallin alpha B
HSP90AA1 heat shock protein 90 alpha family class A member 1
FKBP8 FKBP prolyl isomerase 8
INSR insulin receptor
ADCY9 adenylate cyclase 9
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
ATG5 autophagy related 5
PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2
Symbol Function*
RIM15 protein kinase RIM15
HSP104 chaperone ATPase HSP104
SSA2 Hsp70 family chaperone SSA2
YEF3 translation elongation factor EF-3
SSA1 Hsp70 family ATPase SSA1
SSB1 Hsp70 family ATPase SSB1
HSP42 heat shock protein HSP42
MRPL7 mitochondrial 54S ribosomal protein YmL7/YmL5
HSP78 chaperone ATPase HSP78
MRP1 mitochondrial 37S ribosomal protein MRP1
GGA1 ubiquitin-binding protein
EFT2 elongation factor 2
TOM1 E3 ubiquitin-protein ligase TOM1
SSA3 Hsp70 family ATPase SSA3
TPS1 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1
IRA1 GTPase-activating protein IRA1
SSE2 adenyl-nucleotide exchange factor SSE2
PNC1 nicotinamidase
TPK1 cAMP-dependent protein kinase catalytic subunit TPK1
YJL163C uncharacterized protein
TOR1 phosphatidylinositol kinase-related protein kinase TOR1
RSM26 mitochondrial 37S ribosomal protein RSM26
SOD1 superoxide dismutase SOD1
TOR2 phosphatidylinositol kinase-related protein kinase TOR2
TPK3 cAMP-dependent protein kinase catalytic subunit TPK3
HST1 histone deacetylase HST1
TAO3 Tao3p
TSA1 thioredoxin peroxidase TSA1
SSB2 Hsp70 family ATPase SSB2
BRE5 Bre5p
HSP82 Hsp90 family chaperone HSP82
TPK2 cAMP-dependent protein kinase catalytic subunit TPK2
SOD2 superoxide dismutase SOD2
KOG1 ubiquitin-binding TORC1 subunit KOG1
SSA4 Hsp70 family chaperone SSA4
Symbol Function*
INSR insulin receptor
AKT2 AKT serine/threonine kinase 2
USP4 ubiquitin specific peptidase 4
TTC9 tetratricopeptide repeat domain 9
TNS1 tensin 1
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
UBE2H ubiquitin conjugating enzyme E2 H
IRS1 insulin receptor substrate 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
ADCY6 adenylate cyclase 6
SCP2 sterol carrier protein 2
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
CAT catalase
IRS2 insulin receptor substrate 2
ADCY9 adenylate cyclase 9
PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2
MTOR mechanistic target of rapamycin kinase
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ADCY5 adenylate cyclase 5
ADCY1 adenylate cyclase 1


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