COXPRESdb : KEGG network page for 04068

KEGG 04068 FoxO signaling pathway
[list]

Species

hsa

(Human)

mmu

(Mouse)

rno

(Rat)

gga

(Chicken)

dre

(Zebrafish)

dme

(Fly)

cel

(Nematoda)

mcc

(Monkey)

cfa

(Dog)

fca

(Domestic cat)

UMAP

Representative coexpressed gene network

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
hsa04068	FoxO signaling pathway	38
hsa05200	Pathways in cancer	19
hsa04218	Cellular senescence	17
hsa04010	MAPK signaling pathway	16
hsa05161	Hepatitis B	15

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
mmu04068	FoxO signaling pathway	54
mmu05200	Pathways in cancer	28
mmu04218	Cellular senescence	26
mmu05161	Hepatitis B	25
mmu04010	MAPK signaling pathway	22

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
rno04068	FoxO signaling pathway	51
rno05200	Pathways in cancer	27
rno04151	PI3K-Akt signaling pathway	26
rno04010	MAPK signaling pathway	22
rno04218	Cellular senescence	22

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
gga04068	FoxO signaling pathway	52
gga04218	Cellular senescence	18
gga04910	Insulin signaling pathway	18
gga04110	Cell cycle	17
gga04010	MAPK signaling pathway	16

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
dre04068	FoxO signaling pathway	90
dre04218	Cellular senescence	30
dre04910	Insulin signaling pathway	28
dre04110	Cell cycle	25
dre04140	Autophagy - animal	23

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
dme04068	FoxO signaling pathway	21
dme04140	Autophagy - animal	11
dme04150	mTOR signaling pathway	10
dme04213	Longevity regulating pathway - multiple species	9
dme04137	Mitophagy - animal	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
cel04068	FoxO signaling pathway	27
cel04010	MAPK signaling pathway	13
cel04150	mTOR signaling pathway	10
cel04212	Longevity regulating pathway - worm	9
cel04140	Autophagy - animal	9

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
mcc04068	FoxO signaling pathway	40
mcc05200	Pathways in cancer	20
mcc04218	Cellular senescence	18
mcc05161	Hepatitis B	17
mcc05165	Human papillomavirus infection	14

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
cfa04068	FoxO signaling pathway	47
cfa05200	Pathways in cancer	25
cfa04151	PI3K-Akt signaling pathway	20
cfa04218	Cellular senescence	20
cfa04010	MAPK signaling pathway	18

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
fca04068	FoxO signaling pathway	43
fca04910	Insulin signaling pathway	21
fca05161	Hepatitis B	20
fca05200	Pathways in cancer	20
fca04935	Growth hormone synthesis, secretion and action	18

Gene list in the network

	Symbol	Function^*
	AKT2	AKT serine/threonine kinase 2
	ARAF	A-Raf proto-oncogene, serine/threonine kinase
	CCNA2	cyclin A2
	CCNB1	cyclin B1
	CCNG2	cyclin G2
	CDC20	cell division cycle 20
	CDC34	cell division cycle 34, ubiqiutin conjugating enzyme
	CREBBP	CREB binding protein
	GADD45A	growth arrest and DNA damage inducible alpha
	DNTT	DNA nucleotidylexotransferase
	EP300	E1A binding protein p300
	FOXO1	forkhead box O1
	FOXO3	forkhead box O3
	G6PC1	glucose-6-phosphatase catalytic subunit 1
	IGF1	insulin like growth factor 1
	IGF1R	insulin like growth factor 1 receptor
	GADD45B	growth arrest and DNA damage inducible beta
	PCK1	phosphoenolpyruvate carboxykinase 1
	PDPK1	3-phosphoinositide dependent protein kinase 1
	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
	PLK1	polo like kinase 1
	PRKAA1	protein kinase AMP-activated catalytic subunit alpha 1
	MAPK8	mitogen-activated protein kinase 8
	MAPK11	mitogen-activated protein kinase 11
	MAPK13	mitogen-activated protein kinase 13
	MAP2K2	mitogen-activated protein kinase kinase 2
	RAG1	recombination activating 1
	RAG2	recombination activating 2
	MAPK12	mitogen-activated protein kinase 12
	SKP2	S-phase kinase associated protein 2
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2
	AURKA	aurora kinase A
	STK11	serine/threonine kinase 11
	TGFB2	transforming growth factor beta 2
	TGFB3	transforming growth factor beta 3
	USF2	upstream transcription factor 2, c-fos interacting
	ZFP36	ZFP36 ring finger protein
	CILP	cartilage intermediate layer protein
	IRS2	insulin receptor substrate 2
	CCNB2	cyclin B2
	PTTG1	PTTG1 regulator of sister chromatid separation, securin
	NUP155	nucleoporin 155
	KIF20A	kinesin family member 20A
	KLF2	Kruppel like factor 2
	PLK2	polo like kinase 2
	GADD45G	growth arrest and DNA damage inducible gamma
	ATP11B	ATPase phospholipid transporting 11B (putative)
	MED13L	mediator complex subunit 13L
	SIRT1	sirtuin 1
	BRPF3	bromodomain and PHD finger containing 3
	KLHL24	kelch like family member 24
	ASXL2	ASXL transcriptional regulator 2
	FBXO32	F-box protein 32
	IRAIN	IGF1R antisense imprinted non-protein coding RNA

	Symbol	Function^*
	Akt1	thymoma viral proto-oncogene 1
	Akt2	thymoma viral proto-oncogene 2
	Bcl6	B cell leukemia/lymphoma 6
	Runx1	runt related transcription factor 1
	Ccna2	cyclin A2
	Ccnb2	cyclin B2
	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)
	Cdkn2b	cyclin dependent kinase inhibitor 2B
	Crebbp	CREB binding protein
	Eef2k	eukaryotic elongation factor-2 kinase
	G6pc2	glucose-6-phosphatase, catalytic, 2
	Hras	Harvey rat sarcoma virus oncogene
	Igll1	immunoglobulin lambda-like polypeptide 1
	Il6	interleukin 6
	Ins1	insulin I
	Ins2	insulin II
	Insr	insulin receptor
	Klf2	Kruppel-like factor 2 (lung)
	Mbd3	methyl-CpG binding domain protein 3
	Mdm2	transformed mouse 3T3 cell double minute 2
	Gadd45b	growth arrest and DNA-damage-inducible 45 beta
	Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2
	Pdpk1	3-phosphoinositide dependent protein kinase 1
	Pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1
	Plk1	polo like kinase 1
	Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit
	Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
	Mapk11	mitogen-activated protein kinase 11
	Ptgs2	prostaglandin-endoperoxide synthase 2
	Dusp1	dual specificity phosphatase 1
	Kif20a	kinesin family member 20A
	Rag1	recombination activating 1
	Rag2	recombination activating gene 2
	Sgk1	serum/glucocorticoid regulated kinase 1
	Plk2	polo like kinase 2
	Sos1	SOS Ras/Rac guanine nucleotide exchange factor 1
	Sos2	SOS Ras/Rho guanine nucleotide exchange factor 2
	Stat3	signal transducer and activator of transcription 3
	Stat5a	signal transducer and activator of transcription 5A
	Stk11	serine/threonine kinase 11
	Aurka	aurora kinase A
	Dntt	deoxynucleotidyltransferase, terminal
	Tgfb1	transforming growth factor, beta 1
	Tgfb2	transforming growth factor, beta 2
	Tgfb3	transforming growth factor, beta 3
	Tgfbr2	transforming growth factor, beta receptor II
	Try4	trypsin 4
	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma
	Map2k2	mitogen-activated protein kinase kinase 2
	Mapk1	mitogen-activated protein kinase 1
	Mapk14	mitogen-activated protein kinase 14
	Homer1	homer scaffolding protein 1
	Homer2	homer scaffolding protein 2
	Med14	mediator complex subunit 14
	Phlda3	pleckstrin homology like domain, family A, member 3
	Mapk12	mitogen-activated protein kinase 12
	Foxo4	forkhead box O4
	Mtch1	mitochondrial carrier 1
	Foxo3	forkhead box O3
	Gabarapl1	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
	Jmy	junction-mediating and regulatory protein
	Map1lc3b	microtubule-associated protein 1 light chain 3 beta
	Fbxo32	F-box protein 32
	Setd7	SET domain containing (lysine methyltransferase) 7
	Kif2c	kinesin family member 2C
	Pik3cb	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	Pum1	pumilio RNA-binding family member 1
	Gabarapl2	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
	Csnk1g2	casein kinase 1, gamma 2
	Cdc20	cell division cycle 20
	Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit
	Braf	Braf transforming gene
	Hdac10	histone deacetylase 10
	Daam1	dishevelled associated activator of morphogenesis 1
	Tnrc6b	trinucleotide repeat containing 6b
	Susd6	sushi domain containing 6
	Kmt2c	lysine (K)-specific methyltransferase 2C
	Slc30a8	solute carrier family 30 (zinc transporter), member 8
	Kat6a	K(lysine) acetyltransferase 6A
	Usp7	ubiquitin specific peptidase 7
	Ccnb1	cyclin B1
	Ep300	E1A binding protein p300
	Cdkl5	cyclin-dependent kinase-like 5
	Trim56	tripartite motif-containing 56

	Symbol	Function^*
	Egfr	epidermal growth factor receptor
	Nras	NRAS proto-oncogene, GTPase
	Sod2	superoxide dismutase 2
	Insr	insulin receptor
	Gadd45a	growth arrest and DNA-damage-inducible, alpha
	Ccnb1	cyclin B1
	Egf	epidermal growth factor
	Irs1	insulin receptor substrate 1
	Nfkbia	NFKB inhibitor alpha
	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1
	Plk1	polo-like kinase 1
	Smad3	SMAD family member 3
	G6pc1	glucose-6-phosphatase catalytic subunit 1
	Igf1r	insulin-like growth factor 1 receptor
	Ccng2	cyclin G2
	Prkce	protein kinase C, epsilon
	Sgk1	serum/glucocorticoid regulated kinase 1
	Homer1	homer scaffold protein 1
	S1pr1	sphingosine-1-phosphate receptor 1
	Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha
	Smad4	SMAD family member 4
	Crebbp	CREB binding protein
	Map2k2	mitogen activated protein kinase kinase 2
	Mapk12	mitogen-activated protein kinase 12
	Ccnd2	cyclin D2
	Cdc20	cell division cycle 20
	Bcl2l11	BCL2 like 11
	Prkab2	protein kinase AMP-activated non-catalytic subunit beta 2
	Prkaa1	protein kinase AMP-activated catalytic subunit alpha 1
	Prkaa2	protein kinase AMP-activated catalytic subunit alpha 2
	Mtpn	myotrophin
	Pdpk1	3-phosphoinositide dependent protein kinase-1
	Rbl2	RB transcriptional corepressor like 2
	Tgfb2	transforming growth factor, beta 2
	Cdkn1b	cyclin-dependent kinase inhibitor 1B
	Bnip3	BCL2 interacting protein 3
	Foxo1	forkhead box O1
	Sos2	SOS Ras/Rho guanine nucleotide exchange factor 2
	Braf	B-Raf proto-oncogene, serine/threonine kinase
	Cdkn1a	cyclin-dependent kinase inhibitor 1A
	Dusp1	dual specificity phosphatase 1
	Mapk1	mitogen activated protein kinase 1
	Map2k1	mitogen activated protein kinase kinase 1
	Ipmk	inositol polyphosphate multikinase
	Rnf38	ring finger protein 38
	Plpp3	phospholipid phosphatase 3
	Kpna1	karyopherin subunit alpha 1
	Cdkn3	cyclin-dependent kinase inhibitor 3
	Gadd45g	growth arrest and DNA-damage-inducible, gamma
	Hras	HRas proto-oncogene, GTPase
	Foxo3	forkhead box O3
	Mccc1	methylcrotonyl-CoA carboxylase subunit 1
	Nampt	nicotinamide phosphoribosyltransferase
	Nek9	NIMA-related kinase 9
	Abhd17a	abhydrolase domain containing 17A, depalmitoylase
	Gadd45b	growth arrest and DNA-damage-inducible, beta
	Fbxo11	F-box protein 11
	Klf2	Kruppel-like factor 2
	Gatad2b	GATA zinc finger domain containing 2B
	Knstrn	kinetochore-localized astrin/SPAG5 binding protein
	Fam83d	family with sequence similarity 83, member D
	Stk4	serine/threonine kinase 4
	Sos1	SOS Ras/Rac guanine nucleotide exchange factor 1
	Mdm2	MDM2 proto-oncogene
	Usp7	ubiquitin specific peptidase 7
	Enah	ENAH, actin regulator
	Kif20a	kinesin family member 20A
	Aen	apoptosis enhancing nuclease
	Pck1	phosphoenolpyruvate carboxykinase 1
	Ccnb2	cyclin B2
	Nlk	nemo like kinase
	Klf13	Kruppel-like factor 13
	Ddx6	DEAD-box helicase 6
	Mapk11	mitogen-activated protein kinase 11
	Setd7	SET domain containing 7, histone lysine methyltransferase

	Symbol	Function^*
	MAPK3	mitogen-activated protein kinase 3
	CCND2	cyclin D2
	CDKN1B	cyclin dependent kinase inhibitor 1B
	PAFAH1B1	platelet activating factor acetylhydrolase 1b regulatory subunit 1
	FOXO1	forkhead box O1
	CSNK1E	casein kinase 1 epsilon
	GRB2	growth factor receptor bound protein 2
	USP7	ubiquitin specific peptidase 7
	ATM	ATM serine/threonine kinase
	MDM2	MDM2 proto-oncogene
	IGF1R	insulin like growth factor 1 receptor
	MAPK9	mitogen-activated protein kinase 9
	CCNB3	cyclin B3
	BRAF	B-Raf proto-oncogene, serine/threonine kinase
	CDK1	cyclin dependent kinase 1
	DNTT	DNA nucleotidylexotransferase
	TGFB3	transforming growth factor beta 3
	PCK1	phosphoenolpyruvate carboxykinase 1
	CCNB1	cyclin B1
	EPN2	epsin 2
	PLK1	polo like kinase 1
	PDPK1	3-phosphoinositide dependent protein kinase 1
	CREBBP	CREB binding protein
	KPNA2	karyopherin subunit alpha 2
	NLK	nemo like kinase
	HBP1	HMG-box transcription factor 1
	MAPK11	mitogen-activated protein kinase 11
	EP300	E1A binding protein p300
	TNRC6B	trinucleotide repeat containing adaptor 6B
	FAM76B	family with sequence similarity 76 member B
	RAB22A	RAB22A, member RAS oncogene family
	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
	SPEN	spen family transcriptional repressor
	ZBTB32	zinc finger and BTB domain containing 32
	SLC6A17	solute carrier family 6 member 17
	ELL	elongation factor for RNA polymerase II
	INSR	insulin receptor
	FBXO32	F-box protein 32
	TGFB2	transforming growth factor beta 2
	BTBD9	BTB domain containing 9
	FOXO3	forkhead box O3
	FBXO25	F-box protein 25
	CYP2AC1	cytochrome P450, family 2, subfamily AC, polypeptide 1
	IRS4	insulin receptor substrate 4
	PLK4	polo like kinase 4
	CCNG2	cyclin G2
	MAPK10	mitogen-activated protein kinase 10
	PHLDA2	pleckstrin homology like domain family A member 2
	RAG1	recombination activating 1
	RAG2	recombination activating gene 2
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2
	PTEN	phosphatase and tensin homolog
	BNIP3	BCL2 interacting protein 3
	PRKAG3	protein kinase AMP-activated non-catalytic subunit gamma 3
	CDC20	cell division cycle 20
	PLK3	polo like kinase 3
	RPRD2	regulation of nuclear pre-mRNA domain containing 2
	RBL2	RB transcriptional corepressor like 2
	PRKAB2	protein kinase AMP-activated non-catalytic subunit beta 2
	PLK2	polo like kinase 2
	MTF1	metal regulatory transcription factor 1
	FOXO4	forkhead box O4
	PRKAA2	protein kinase AMP-activated catalytic subunit alpha 2
	PRKAG1	protein kinase AMP-activated non-catalytic subunit gamma 1
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1
	GADD45A	growth arrest and DNA damage inducible alpha
	BMF	Bcl2 modifying factor
	MAPK12	mitogen-activated protein kinase 12
	PRC1	protein regulator of cytokinesis 1
	PAPD7	poly(A) RNA polymerase D7, non-canonical
	SON	SON DNA binding protein
	CKS1B	CDC28 protein kinase regulatory subunit 1B
	CDK2	cyclin dependent kinase 2
	G6PC	glucose-6-phosphatase catalytic subunit
	UBE2U	ubiquitin conjugating enzyme E2 U (putative)
	GADD45B	growth arrest and DNA damage inducible beta
	IRS2	insulin receptor substrate 2
	ZBTB44	zinc finger and BTB domain containing 44
	BCL2L11	BCL2 like 11

	Symbol	Function^*
	ccnd1	cyclin D1
	gja1b	gap junction protein alpha 1b
	ins	preproinsulin
	foxo3b	forkhead box O3b
	mdm2	MDM2 proto-oncogene
	rag2	recombination activating gene 2
	rag1	recombination activating 1
	stat3	signal transducer and activator of transcription 3 (acute-phase response factor)
	ccnb1	cyclin B1
	smad3a	SMAD family member 3a
	s1pr1	sphingosine-1-phosphate receptor 1
	mapk8b	mitogen-activated protein kinase 8b
	klf2a	Kruppel-like factor 2a
	klf2b	Kruppel-like factor 2b
	cebpd	CCAAT enhancer binding protein delta
	insra	insulin receptor a
	insrb	insulin receptor b
	igf1ra	insulin-like growth factor 1a receptor
	igf1rb	insulin-like growth factor 1b receptor
	ccng2	cyclin G2
	plk1	polo-like kinase 1 (Drosophila)
	tnrc6b	trinucleotide repeat containing adaptor 6B
	atp6v0b	ATPase H+ transporting V0 subunit b
	prmt1	protein arginine methyltransferase 1
	map1lc3b	microtubule-associated protein 1 light chain 3 beta
	si:ch1073-335m2.2	si:ch1073-335m2.2
	dennd5b	DENN/MADD domain containing 5B
	sgk1	serum/glucocorticoid regulated kinase 1
	smad3b	SMAD family member 3b
	pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
	gabarapa	GABA(A) receptor-associated protein a
	hsd11b2	hydroxysteroid (11-beta) dehydrogenase 2
	plk3	polo-like kinase 3 (Drosophila)
	socs3a	suppressor of cytokine signaling 3a
	tgfb1a	transforming growth factor, beta 1a
	ccnb2	cyclin B2
	cdkn1bb	cyclin-dependent kinase inhibitor 1Bb
	plk4	polo-like kinase 4 (Drosophila)
	phlda3	pleckstrin homology-like domain, family A, member 3
	fkbp5	FKBP prolyl isomerase 5
	pck1	phosphoenolpyruvate carboxykinase 1 (soluble)
	sox8b	SRY-box transcription factor 8b
	rasl11b	RAS-like, family 11, member B
	fibpa	fibroblast growth factor (acidic) intracellular binding protein a
	klhl24b	kelch-like family member 24b
	gadd45aa	growth arrest and DNA-damage-inducible, alpha, a
	gmps	guanine monophosphate synthase
	bcl6aa	BCL6A transcription repressor a
	arl5c	ADP-ribosylation factor-like 5C
	fbxo32	F-box protein 32
	homer3b	homer scaffold protein 3b
	mapk3	mitogen-activated protein kinase 3
	zgc:73226	zgc:73226
	s1pr4	sphingosine-1-phosphate receptor 4
	gadd45ga	growth arrest and DNA-damage-inducible, gamma a
	gabarapl2	GABA(A) receptor-associated protein like 2
	pik3r2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)
	foxg1b	forkhead box G1b
	gadd45ba	growth arrest and DNA-damage-inducible, beta a
	grb2b	growth factor receptor-bound protein 2b
	pik3r3a	phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
	cdc20	cell division cycle 20 homolog
	slc37a4a	solute carrier family 37 member 4a
	pck2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
	slc25a25a	solute carrier family 25 member 25a
	mapk11	mitogen-activated protein kinase 11
	gadd45ab	growth arrest and DNA-damage-inducible, alpha, b
	ip6k2b	inositol hexakisphosphate kinase 2b
	homer1b	homer scaffold protein 1b
	g6pc1a.1	glucose-6-phosphatase catalytic subunit 1a, tandem duplicate 1
	aurka	aurora kinase A
	pptc7a	protein phosphatase targeting COQ7 a
	gcga	glucagon a
	foxo3a	forkhead box O3A
	ext1b	exostosin glycosyltransferase 1b
	gadd45bb	growth arrest and DNA-damage-inducible, beta b
	asb5b	ankyrin repeat and SOCS box containing 5b
	prkag3a	protein kinase, AMP-activated, gamma 3a non-catalytic subunit
	homer2	homer scaffold protein 2
	usp7	ubiquitin specific peptidase 7 (herpes virus-associated)
	bnip3lb	BCL2 interacting protein 3 like b
	si:ch211-260e23.9	si:ch211-260e23.9
	setd1a	SET domain containing 1A, histone lysine methyltransferase
	npdc1b	neural proliferation, differentiation and control, 1b
	uroc1	urocanate hydratase 1
	kmt2a	lysine (K)-specific methyltransferase 2A
	rasgrp2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
	pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
	osbpl2a	oxysterol binding protein-like 2a
	trioa	trio Rho guanine nucleotide exchange factor a
	mapk12b	mitogen-activated protein kinase 12b
	sgk2b	serum/glucocorticoid regulated kinase 2b
	ep300a	E1A binding protein p300 a
	irs1	insulin receptor substrate 1
	smad10a	SMAD family member 10a
	akt3a	v-akt murine thymoma viral oncogene homolog 3a
	sos2	son of sevenless homolog 2 (Drosophila)
	pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
	rnf19b	ring finger protein 19B
	g6pc1a.2	glucose-6-phosphatase catalytic subunit 1a, tandem duplicate 2
	foxo4	forkhead box O4
	tgfb1b	transforming growth factor, beta 1b
	cdca3	cell division cycle associated 3
	sgk3	serum/glucocorticoid regulated kinase family member 3
	ddr2l	discoidin domain receptor family, member 2, like
	pnrc2	proline-rich nuclear receptor coactivator 2
	plk2b	polo-like kinase 2b (Drosophila)
	ep300b	E1A binding protein p300 b
	atxn1b	ataxin 1b
	LOC566587	ERBB receptor feedback inhibitor 1-like
	crebbpa	CREB binding protein a
	crebbpb	CREB binding protein b
	prr11	proline rich 11
	fbxo33	F-box protein 33
	foxo1b	forkhead box O1 b
	bnip4	BCL2 interacting protein 4
	prkag2a	protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
	irs2b	insulin receptor substrate 2b
	prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit
	ccnb3	cyclin B3
	foxo1a	forkhead box O1 a
	si:ch211-195b13.1	si:ch211-195b13.1
	pdpk1a	3-phosphoinositide dependent protein kinase 1a
	atg9b	autophagy related 9B
	aurkb	aurora kinase B
	gabarapb	GABA(A) receptor-associated protein b
	pcnx1	pecanex 1
	LOC794462	insulin receptor substrate 2-B-like
	bsdc1	BSD domain containing 1
	rnf169	ring finger protein 169
	ppp1r15a	protein phosphatase 1, regulatory subunit 15A
	ccnd2a	cyclin D2, a
	zgc:92606	zgc:92606
	g6pc1b	glucose-6-phosphatase catalytic subunit 1b
	bcl6ab	BCL6A transcription repressor b
	si:ch73-63e15.2	si:ch73-63e15.2
	mapk13	mitogen-activated protein kinase 13
	cep350	centrosomal protein 350
	plk2a	polo-like kinase 2a (Drosophila)
	cdkn1a	cyclin-dependent kinase inhibitor 1A
	prkab2	protein kinase, AMP-activated, beta 2 non-catalytic subunit
	irs4a	insulin receptor substrate 4a
	ier2b	immediate early response 2b
	rbl2	retinoblastoma-like 2 (p130)
	LOC100334443	mRNA decay activator protein ZFP36L1-like
	gan	gigaxonin
	mdfi	MyoD family inhibitor
	nfe2l2b	nuclear factor, erythroid 2-like 2b
	tpx2	TPX2 microtubule nucleation factor

	Symbol	Function^*
	Atg8a	Autophagy-related 8a
	GstT4	Glutathione S transferase T4
	e(y)3	enhancer of yellow 3
	homer	homer
	borr	borealin-related
	pim	pimples
	Sirt1	Sirtuin 1
	msb1l	msb1l
	CycB	Cyclin B
	Pdk1	Phosphoinositide-dependent kinase 1
	CG7083	uncharacterized protein
	Ilp2	Insulin-like peptide 2
	Ilp3	Insulin-like peptide 3
	nudE	nudE
	CycA	Cyclin A
	Nedd4	Nedd4
	Cat	Catalase
	polo	polo
	CG5059	uncharacterized protein
	Csk	C-terminal Src kinase
	Akt1	Akt1
	Pi3K92E	Phosphatidylinositol 3-kinase 92E
	InR	Insulin-like receptor
	p38a	p38a MAP kinase
	CycB3	Cyclin B3
	Med	Medea
	nej	nejire
	Pten	Phosphatase and tensin homolog
	IKKbeta	I-kappaB kinase beta
	gwl	greatwall
	chico	chico
	Ilp5	Insulin-like peptide 5
	SIFa	SIFamide

	Symbol	Function^*
	cyb-2.2	Cyclin N-terminal domain-containing protein
	goa-1	Guanine nucleotide-binding protein G(o) subunit alpha
	pck-2	Phosphoenolpyruvate carboxykinase (GTP)
	daf-16	Fork-head domain-containing protein;Forkhead box protein O
	lgg-1	Protein lgg-1
	cdc-42	Cell division control protein 42 homolog
	F18A1.7	CPG4 domain-containing protein
	jun-1	BZIP domain-containing protein;Transcription factor jun-1
	pck-1	Phosphoenolpyruvate carboxykinase (GTP)
	daf-2	Insulin-like receptor subunit beta;Protein kinase domain-containing protein;Receptor protein-tyrosine kinase
	mpk-1	Mitogen-activated protein kinase mpk-1
	sma-4	Dwarfin sma-4;MH2 domain-containing protein
	plk-1	Serine/threonine-protein kinase plk-1
	lit-1	Serine/threonine kinase NLK
	fkh-7	Fork-head domain-containing protein
	lin-45	Raf homolog serine/threonine-protein kinase
	pitr-1	Phosphate transporter
	pmk-3	Mitogen-activated protein kinase pmk-3;Protein kinase domain-containing protein
	pmk-2	Mitogen-activated protein kinase;Mitogen-activated protein kinase pmk-2
	cyb-1	G2/mitotic-specific cyclin-B1
	lgg-2	Protein lgg;Protein lgg-2
	cyb-2.1	Cyclin N-terminal domain-containing protein
	kin-4	Non-specific serine/threonine protein kinase
	let-60	Ras protein let-60
	fbxa-215	F-box domain-containing protein
	mcm-7	DNA replication licensing factor MCM7
	sos-1	Son of sevenless homolog
	akt-1	Serine/threonine-protein kinase akt-1
	ZC443.3	Uncharacterized protein
	par-1	Serine/threonine-protein kinase par-1
	T01C3.3	RING-type domain-containing protein
	cyb-3	G2/mitotic-specific cyclin-B3
	gpd-3	Glyceraldehyde-3-phosphate dehydrogenase 3
	ist-1	Insulin receptor SubsTrate homolog
	dct-1	NIP3 homolog
	sem-5	Sex muscle abnormal protein 5
	F34H10.3	Uncharacterized protein
	akt-2	Serine/threonine-protein kinase akt-2
	aak-2	5'-AMP-activated protein kinase catalytic subunit alpha-2
	mfb-1	F-box domain-containing protein
	islo-1	Interactor with SLO-1
	aakg-4	AMP-Activated protein Kinase Gamma subunit
	pmk-1	Mitogen-activated protein kinase pmk-1
	gap-3	GTPase Activating Protein family
	fzy-1	WD repeat-containing protein fzy-1
	Y105E8A.25	DH domain-containing protein
	aakg-1	AMP-Activated protein Kinase Gamma subunit

	Symbol	Function^*
	ATP6V0A1	ATPase H+ transporting V0 subunit a1
	HIPK3	homeodomain interacting protein kinase 3
	CSRNP1	cysteine and serine rich nuclear protein 1
	FOXP1	forkhead box P1
	PTTG1	PTTG1 regulator of sister chromatid separation, securin
	CCNF	cyclin F
	BCL2L11	BCL2 like 11
	RAG1	recombination activating 1
	PLK1	polo like kinase 1
	CNOT6L	CCR4-NOT transcription complex subunit 6 like
	FOXO4	forkhead box O4
	RMND5A	required for meiotic nuclear division 5 homolog A
	IRS2	insulin receptor substrate 2
	PIK3R1	phosphoinositide-3-kinase regulatory subunit 1
	CCNB1	cyclin B1
	CCNG2	cyclin G2
	FOXO1	forkhead box O1
	CYP27A1	cytochrome P450 family 27 subfamily A member 1
	SETD7	SET domain containing 7, histone lysine methyltransferase
	FOXO3	forkhead box O3
	SERTAD1	SERTA domain containing 1
	CCNB2	cyclin B2
	GRAP	GRB2-related adaptor protein
	PRKAG3	protein kinase AMP-activated non-catalytic subunit gamma 3
	CREBBP	CREB binding protein
	FBXO32	F-box protein 32
	PTEN	phosphatase and tensin homolog
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2
	STK11	serine/threonine kinase 11
	INSR	insulin receptor
	EP300	E1A binding protein p300
	CHD2	chromodomain helicase DNA binding protein 2
	CCNA2	cyclin A2
	IGF1R	insulin like growth factor 1 receptor
	MAPK3	mitogen-activated protein kinase 3
	CENPM	centromere protein M
	BIRC5	baculoviral IAP repeat containing 5
	HOMER1	homer scaffold protein 1
	MAPK8	mitogen-activated protein kinase 8
	GADD45B	growth arrest and DNA damage inducible beta
	S1PR4	sphingosine-1-phosphate receptor 4
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1
	AKT3	AKT serine/threonine kinase 3
	TGFBR1	transforming growth factor beta receptor 1
	MAPK12	mitogen-activated protein kinase 12
	MAPK11	mitogen-activated protein kinase 11
	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	FBXO25	F-box protein 25
	S1PR1	sphingosine-1-phosphate receptor 1
	RAG2	recombination activating 2
	PTPA	protein phosphatase 2 phosphatase activator
	KANSL1	KAT8 regulatory NSL complex subunit 1
	TNRC18	trinucleotide repeat containing 18
	KIAA2026	KIAA2026
	STK4	serine/threonine kinase 4
	RAB21	RAB21, member RAS oncogene family
	MAPK14	mitogen-activated protein kinase 14
	BRPF3	bromodomain and PHD finger containing 3
	CDKN1A	cyclin dependent kinase inhibitor 1A
	PIK3R2	phosphoinositide-3-kinase regulatory subunit 2
	HOMER3	homer scaffold protein 3
	ARID1A	AT-rich interaction domain 1A

	Symbol	Function^*
	SCN5A	sodium voltage-gated channel alpha subunit 5
	PCK1	phosphoenolpyruvate carboxykinase 1
	SGK1	serum/glucocorticoid regulated kinase 1
	AGT	angiotensinogen
	NRAS	NRAS proto-oncogene, GTPase
	EGFR	epidermal growth factor receptor
	IGF1R	insulin like growth factor 1 receptor
	APOC3	apolipoprotein C3
	CCNB3	cyclin B3
	TCP11L2	t-complex 11 like 2
	KIF20A	kinesin family member 20A
	CDKN1A	cyclin dependent kinase inhibitor 1A
	BICRAL	BRD4 interacting chromatin remodeling complex associated protein like
	FBXO32	F-box protein 32
	CSDE1	cold shock domain containing E1
	HBP1	HMG-box transcription factor 1
	PLK4	polo like kinase 4
	SOD2	superoxide dismutase 2
	DDA1	DET1 and DDB1 associated 1
	STK4	serine/threonine kinase 4
	TAF4	TATA-box binding protein associated factor 4
	FOXO1	forkhead box O1
	MAPK8	mitogen-activated protein kinase 8
	CHUK	component of inhibitor of nuclear factor kappa B kinase complex
	RBL2	RB transcriptional corepressor like 2
	KNL1	kinetochore scaffold 1
	CCNB2	cyclin B2
	CCNG2	cyclin G2
	KLHL24	kelch like family member 24
	ARID5B	AT-rich interaction domain 5B
	POLR2A	RNA polymerase II subunit A
	CREBBP	CREB binding protein
	PDPK1	3-phosphoinositide dependent protein kinase 1
	CA4	carbonic anhydrase 4
	SPAG5	sperm associated antigen 5
	PIM1	Pim-1 proto-oncogene, serine/threonine kinase
	GRB2	growth factor receptor bound protein 2
	RAG2	recombination activating 2
	RAG1	recombination activating 1
	CCNA2	cyclin A2
	GADD45G	growth arrest and DNA damage inducible gamma
	ZFP36	ZFP36 ring finger protein
	HOMER3	homer scaffold protein 3
	FKBP8	FKBP prolyl isomerase 8
	INSR	insulin receptor
	GADD45B	growth arrest and DNA damage inducible beta
	IRS2	insulin receptor substrate 2
	AURKA	aurora kinase A
	PIK3R1	phosphoinositide-3-kinase regulatory subunit 1
	ARID1A	AT-rich interaction domain 1A
	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
	BCL6	BCL6 transcription repressor
	PRKAG3	protein kinase AMP-activated non-catalytic subunit gamma 3
	DUSP1	dual specificity phosphatase 1
	OSMR	oncostatin M receptor
	PLK1	polo like kinase 1
	UBN1	ubinuclein 1
	MAPKAPK2	MAPK activated protein kinase 2
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2
	AKT1	AKT serine/threonine kinase 1
	STAT3	signal transducer and activator of transcription 3
	MAPK12	mitogen-activated protein kinase 12
	ENTPD7	ectonucleoside triphosphate diphosphohydrolase 7
	CCNB1	cyclin B1
	PIK3R2	phosphoinositide-3-kinase regulatory subunit 2
	SGK2	serum/glucocorticoid regulated kinase 2
	MAP2K2	mitogen-activated protein kinase kinase 2
	MAPK13	mitogen-activated protein kinase 13
	ATF3	activating transcription factor 3
	GABARAPL1	GABA type A receptor associated protein like 1
	EP300	E1A binding protein p300
	SPEN	spen family transcriptional repressor
	GADD45A	growth arrest and DNA damage inducible alpha
	LOC100856339	phosphatidylinositol 3-kinase regulatory subunit gamma
	PRKAB2	protein kinase AMP-activated non-catalytic subunit beta 2
	CRAMP1	cramped chromatin regulator homolog 1
	KLF2	Kruppel like factor 2
	KANSL1	KAT8 regulatory NSL complex subunit 1

	Symbol	Function^*
	IL6	interleukin 6
	LRCH1	leucine rich repeats and calponin homology domain containing 1
	INSR	insulin receptor
	KLHL38	kelch like family member 38
	NR3C1	nuclear receptor subfamily 3 group C member 1
	CCNB2	cyclin B2
	MAP2K1	mitogen-activated protein kinase kinase 1
	CCNB3	cyclin B3
	SOCS3	suppressor of cytokine signaling 3
	TMOD1	tropomodulin 1
	PHF3	PHD finger protein 3
	FBXO32	F-box protein 32
	TOP2A	DNA topoisomerase II alpha
	GABARAPL1	GABA type A receptor associated protein like 1
	KMT2E	lysine methyltransferase 2E (inactive)
	HOMER1	homer scaffold protein 1
	UBE2H	ubiquitin conjugating enzyme E2 H
	MAPK1	mitogen-activated protein kinase 1
	AKT1	AKT serine/threonine kinase 1
	GADD45B	growth arrest and DNA damage inducible beta
	DCP1A	decapping mRNA 1A
	EP300	E1A binding protein p300
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2
	PCK1	phosphoenolpyruvate carboxykinase 1
	MTMR3	myotubularin related protein 3
	ARAF	A-Raf proto-oncogene, serine/threonine kinase
	FOXO4	forkhead box O4
	NFKBIA	NFKB inhibitor alpha
	SERINC3	serine incorporator 3
	ARID1B	AT-rich interaction domain 1B
	STK4	serine/threonine kinase 4
	SETD7	SET domain containing 7, histone lysine methyltransferase
	S1PR1	sphingosine-1-phosphate receptor 1
	MAPK8	mitogen-activated protein kinase 8
	DPP9	dipeptidyl peptidase 9
	PRKAG3	protein kinase AMP-activated non-catalytic subunit gamma 3
	PRKAB2	protein kinase AMP-activated non-catalytic subunit beta 2
	LIMD1	LIM domain containing 1
	CDC42SE2	CDC42 small effector 2
	SCP2	sterol carrier protein 2
	PIK3R2	phosphoinositide-3-kinase regulatory subunit 2
	SMAD4	SMAD family member 4
	CAT	catalase
	CREBBP	CREB binding protein
	SLC2A4	solute carrier family 2 member 4
	STAT3	signal transducer and activator of transcription 3
	SGK2	serum/glucocorticoid regulated kinase 2
	IRS2	insulin receptor substrate 2
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase
	BCL6	BCL6 transcription repressor
	PHKA1	phosphorylase kinase regulatory subunit alpha 1
	GABARAPL2	GABA type A receptor associated protein like 2
	HOMER2	homer scaffold protein 2
	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
	RBL2	RB transcriptional corepressor like 2
	FHL1	four and a half LIM domains 1
	MTMR1	myotubularin related protein 1
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1
	FLII	FLII actin remodeling protein
	GRB2	growth factor receptor bound protein 2
	WDR45	WD repeat domain 45
	PRKAG2	protein kinase AMP-activated non-catalytic subunit gamma 2
	MAP2K2	mitogen-activated protein kinase kinase 2
	SLC22A12	solute carrier family 22 member 12
	MAPK14	mitogen-activated protein kinase 14
	GPATCH8	G-patch domain containing 8
	LOC109497903	uncharacterized LOC109497903
	MAPK12	mitogen-activated protein kinase 12
	KLF2	Kruppel like factor 2

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