KEGG 01210 2-Oxocarboxylic acid metabolism
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) dme(Fly) cel(Nematoda) mcc(Monkey) cfa(Dog) sce(Budding yeast) spo(Fission yeast) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa01230 Biosynthesis of amino acids 11
hsa01200 Carbon metabolism 10
hsa01210 2-Oxocarboxylic acid metabolism 10
hsa00020 Citrate cycle (TCA cycle) 6
hsa00270 Cysteine and methionine metabolism 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu01200 Carbon metabolism 14
mmu01230 Biosynthesis of amino acids 13
mmu01210 2-Oxocarboxylic acid metabolism 12
mmu00020 Citrate cycle (TCA cycle) 10
mmu00270 Cysteine and methionine metabolism 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno01200 Carbon metabolism 13
rno01210 2-Oxocarboxylic acid metabolism 12
rno01230 Biosynthesis of amino acids 12
rno00020 Citrate cycle (TCA cycle) 9
rno00220 Arginine biosynthesis 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga01200 Carbon metabolism 10
gga01210 2-Oxocarboxylic acid metabolism 10
gga01230 Biosynthesis of amino acids 10
gga00020 Citrate cycle (TCA cycle) 8
gga00630 Glyoxylate and dicarboxylate metabolism 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre01210 2-Oxocarboxylic acid metabolism 12
dre01230 Biosynthesis of amino acids 11
dre01200 Carbon metabolism 10
dre00020 Citrate cycle (TCA cycle) 7
dre00220 Arginine biosynthesis 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme01210 2-Oxocarboxylic acid metabolism 12
dme01230 Biosynthesis of amino acids 12
dme01200 Carbon metabolism 10
dme00020 Citrate cycle (TCA cycle) 8
dme00220 Arginine biosynthesis 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel01230 Biosynthesis of amino acids 15
cel01210 2-Oxocarboxylic acid metabolism 14
cel01200 Carbon metabolism 13
cel00020 Citrate cycle (TCA cycle) 9
cel00220 Arginine biosynthesis 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc01210 2-Oxocarboxylic acid metabolism 7
mcc01230 Biosynthesis of amino acids 7
mcc01200 Carbon metabolism 6
mcc00020 Citrate cycle (TCA cycle) 5
mcc00190 Oxidative phosphorylation 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa01200 Carbon metabolism 7
cfa01210 2-Oxocarboxylic acid metabolism 6
cfa01230 Biosynthesis of amino acids 6
cfa00020 Citrate cycle (TCA cycle) 4
cfa00220 Arginine biosynthesis 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sce01230 Biosynthesis of amino acids 43
sce01210 2-Oxocarboxylic acid metabolism 31
sce00300 Lysine biosynthesis 11
sce00290 Valine, leucine and isoleucine biosynthesis 10
sce00220 Arginine biosynthesis 10
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
spo01230 Biosynthesis of amino acids 35
spo01210 2-Oxocarboxylic acid metabolism 26
spo01200 Carbon metabolism 14
spo00220 Arginine biosynthesis 9
spo00020 Citrate cycle (TCA cycle) 9
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca01200 Carbon metabolism 9
fca01210 2-Oxocarboxylic acid metabolism 8
fca01230 Biosynthesis of amino acids 8
fca00020 Citrate cycle (TCA cycle) 7
fca00630 Glyoxylate and dicarboxylate metabolism 3
Gene list in the network
Symbol Function*
ACO1 aconitase 1
ACO2 aconitase 2
ATP5F1B ATP synthase F1 subunit beta
BCAT1 branched chain amino acid transaminase 1
CS citrate synthase
GOT1 glutamic-oxaloacetic transaminase 1
GOT2 glutamic-oxaloacetic transaminase 2
HSD17B4 hydroxysteroid 17-beta dehydrogenase 4
IDH1 isocitrate dehydrogenase (NADP(+)) 1
IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1
PSAT1 phosphoserine aminotransferase 1
GPT2 glutamic--pyruvic transaminase 2
Symbol Function*
Aco1 aconitase 1
Aco2 aconitase 2, mitochondrial
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
Bcat1 branched chain aminotransferase 1, cytosolic
Bcat2 branched chain aminotransferase 2, mitochondrial
Bckdk branched chain ketoacid dehydrogenase kinase
Cs citrate synthase
Got1 glutamic-oxaloacetic transaminase 1, soluble
Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial
Idh1 isocitrate dehydrogenase 1 (NADP+), soluble
Idh3g isocitrate dehydrogenase 3 (NAD+), gamma
Mdh2 malate dehydrogenase 2, NAD (mitochondrial)
Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1
Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Idh3a isocitrate dehydrogenase 3 (NAD+) alpha
Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12
Psat1 phosphoserine aminotransferase 1
Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2
Idh3b isocitrate dehydrogenase 3 (NAD+) beta
Dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
Symbol Function*
Got1 glutamic-oxaloacetic transaminase 1
Idh1 isocitrate dehydrogenase (NADP(+)) 1
Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
Atp1b1 ATPase Na+/K+ transporting subunit beta 1
Got2 glutamic-oxaloacetic transaminase 2
Aco1 aconitase 1
Acox1 acyl-CoA oxidase 1
Bcat2 branched chain amino acid transaminase 2
Aco2 aconitase 2
Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
Echs1 enoyl-CoA hydratase, short chain 1
Cs citrate synthase
Slc25a10 solute carrier family 25 member 10
Atp5f1b ATP synthase F1 subunit beta
Acy1 aminoacylase 1
Ogdh oxoglutarate dehydrogenase
Idh2 isocitrate dehydrogenase (NADP(+)) 2
Symbol Function*
ACO1 aconitase 1, soluble
ACO2 aconitase 2
GOT1 glutamic-oxaloacetic transaminase 1
GOT2 glutamic-oxaloacetic transaminase 2
IDH3A isocitrate dehydrogenase 3 (NAD(+)) alpha
MDH1 malate dehydrogenase 1
IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic
IDH3B isocitrate dehydrogenase 3 (NAD(+)) beta
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
UQCRC2 ubiquinol-cytochrome c reductase core protein II
IDH2 isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2
ACY1 aminoacylase 1
CS citrate synthase
Symbol Function*
cs citrate synthase
aco2 aconitase 2, mitochondrial
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial
idh2 isocitrate dehydrogenase (NADP(+)) 2
uqcrc1 ubiquinol-cytochrome c reductase core protein 1
idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
acy1 aminoacylase 1
got1 glutamic-oxaloacetic transaminase 1, soluble
got2a glutamic-oxaloacetic transaminase 2a, mitochondrial
slc25a11 solute carrier family 25 member 11
idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
ndufs1 NADH:ubiquinone oxidoreductase core subunit S1
atp5fa1 ATP synthase F1 subunit alpha
atp5f1b ATP synthase F1 subunit beta
aadat aminoadipate aminotransferase
aco1 aconitase 1, soluble
gusb glucuronidase, beta
LOC100001620 aminoacylase-1A-like
trim 35-44 tripartite motif containing 35-44
Symbol Function*
kdn knockdown
Idh3a Isocitrate dehydrogenase 3a
Got2 Glutamate oxaloacetate transaminase 2
Etf-QO Electron transfer flavoprotein-ubiquinone oxidoreductase
Got1 Glutamate oxaloacetate transaminase 1
SdhA Succinate dehydrogenase, subunit A (flavoprotein)
blw bellwether
Irp-1B Iron regulatory protein 1B
Idh3b Isocitrate dehydrogenase 3b
CG17109 uncharacterized protein
CG6733 uncharacterized protein
CG6738 uncharacterized protein
CG5028 uncharacterized protein
mAcon1 Mitochondrial aconitase 1
Idh Isocitrate dehydrogenase
Symbol Function*
W10C8.5 Arginine kinase
C32F10.8 Aminotran_1_2 domain-containing protein
idhg-2 Isocitrate dehydrogenase [NAD] subunit, mitochondrial
idha-1 putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
enol-1 Enolase
idhg-1 Isocitrate dehydrogenase [NAD] subunit, mitochondrial
aco-2 putative aconitate hydratase, mitochondrial
cts-1 putative citrate synthase, mitochondrial
isp-1 Cytochrome b-c1 complex subunit Rieske, mitochondrial
C10C5.3 N-acyl-L-amino-acid amidohydrolase
C10C5.4 N-acyl-L-amino-acid amidohydrolase
C10C5.5 N-acyl-L-amino-acid amidohydrolase
idh-1 Isocitrate dehydrogenase [NADP]
F01G4.6 Phosphate carrier protein, mitochondrial
ugt-4 UDP-glucuronosyltransferase
immt-1 MICOS complex subunit MIC60-1
pccb-1 Propionyl Coenzyme A Carboxylase Beta subunit
got-2.2 Aspartate aminotransferase
idh-2 Isocitrate dehydrogenase [NADP]
aco-1 putative cytoplasmic aconitate hydratase
idhb-1 putative isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
plep-1 PLugged Excretory Pore
Symbol Function*
UQCRC1 ubiquinol-cytochrome c reductase core protein 1
LOC698851 aminoacylase-1
OGDH oxoglutarate dehydrogenase
ATP5F1A ATP synthase F1 subunit alpha
IDH2 isocitrate dehydrogenase (NADP(+)) 2
ACO2 aconitase 2
GOT1 glutamic-oxaloacetic transaminase 1
CS citrate synthase
IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
BCAT2 branched chain amino acid transaminase 2
GAMT guanidinoacetate N-methyltransferase
Symbol Function*
ATP5F1B ATP synthase F1 subunit beta
CS citrate synthase
ACO2 aconitase 2
IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
MCCC2 methylcrotonyl-CoA carboxylase subunit 2
GOT2 glutamic-oxaloacetic transaminase 2
SDHA succinate dehydrogenase complex flavoprotein subunit A
PANK1 pantothenate kinase 1
GOT1 glutamic-oxaloacetic transaminase 1
GPT2 glutamic--pyruvic transaminase 2
Symbol Function*
LEU2 3-isopropylmalate dehydrogenase
ILV6 acetolactate synthase regulatory subunit
CIT2 citrate (Si)-synthase CIT2
ISA1 Fe-binding Fe/S cluster assembly protein ISA1
AAT2 aspartate transaminase AAT2
ALT1 alanine transaminase ALT1
UPS2 Ups2p
ACO1 aconitate hydratase ACO1
ILV5 ketol-acid reductoisomerase
GDH2 glutamate dehydrogenase (NAD(+))
LYS20 homocitrate synthase LYS20
UGA3 Uga3p
LYS21 homocitrate synthase LYS21
ARO3 3-deoxy-7-phosphoheptulonate synthase ARO3
ALT2 alanine transaminase ALT2
ARO1 pentafunctional protein ARO1p
HOM2 aspartate-semialdehyde dehydrogenase
LYS4 homoaconitate hydratase LYS4
LYS2 L-aminoadipate-semialdehyde dehydrogenase
ARO4 3-deoxy-7-phosphoheptulonate synthase ARO4
CTP1 Ctp1p
ARO8 bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase
TRP5 tryptophan synthase TRP5
LEU1 3-isopropylmalate dehydratase LEU1
ACO2 aconitate hydratase ACO2
ARG3 ornithine carbamoyltransferase
ARG2 acetyl-CoA:L-glutamate N-acetyltransferase
ILV3 dihydroxy-acid dehydratase ILV3
CPA2 carbamoyl-phosphate synthase (glutamine-hydrolyzing) CPA2
BAT2 branched-chain-amino-acid transaminase BAT2
OAC1 Oac1p
ARG8 acetylornithine transaminase
ARG1 argininosuccinate synthase
LEU9 2-isopropylmalate synthase LEU9
IDH2 isocitrate dehydrogenase (NAD(+)) IDH2
HIS3 imidazoleglycerol-phosphate dehydratase HIS3
ODC2 mitochondrial 2-oxodicarboxylate carrier
FSF1 Fsf1p
LYS12 homoisocitrate dehydrogenase
LYS1 saccharopine dehydrogenase (NAD+, L-lysine-forming)
ARG7 glutamate N-acetyltransferase
ILV2 acetolactate synthase catalytic subunit
LEU4 2-isopropylmalate synthase LEU4
IDH1 isocitrate dehydrogenase (NAD(+)) IDH1
CIT1 citrate (Si)-synthase CIT1
LYS9 saccharopine dehydrogenase (NADP+, L-glutamate-forming)
CIT3 citrate (Si)-synthase CIT3
PDH1 putative 2-methylcitrate dehydratase
THR1 homoserine kinase
BAT1 branched-chain-amino-acid transaminase BAT1
GLY1 threonine aldolase GLY1
YAT2 carnitine O-acetyltransferase YAT2
HOM3 aspartate kinase
ARG5,6 bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase
ALD5 aldehyde dehydrogenase (NAD(P)(+)) ALD5
Symbol Function*
arg1 acetylornithine aminotransferase
SPCC306.08c putative malate dehydrogenase
SPCC569.07 putative aromatic aminotransferase
lat1 putative dihydrolipoamide S-acetyltransferase E2 Lat1
SPCC1827.06c putative aspartate semialdehyde dehydrogenase
SPCC70.03c putative proline dehydrogenase
asn1 asparagine synthetase
SPBC1271.14 putative glutamate N-acetyltransferase
lys4 putative homocitrate synthase
trp1 putative anthranilate synthase component II
SPBC14C8.04 putative acetolactate synthase regulatory subunit protein
SPBC1677.03c putative threonine ammonia-lyase
pdb1 pyruvate dehydrogenase e1 component beta subunit Pdb1
leu1 3-isopropylmalate dehydrogenase Leu1
SPBC19F5.04 putative aspartate kinase
eca39 branched chain amino acid aminotransferase Eca39
SPBC582.08 putative alanine aminotransferase
leu3 2-isopropylmalate synthase Leu3
arg12 putative argininosuccinate synthase
arg5 putative arginine specific carbamoyl-phosphate synthase subunit Arg5
arg6 putative acetylglutamate synthase Arg6
SPBC725.01 putative aspartate aminotransferase
irs1 putative isoleucine--tRNA(Ile) ligase Irs1
idh2 isocitrate dehydrogenase (NAD+) subunit 2
ilv1 acetolactate synthase catalytic subunit
SPAC24C9.06c putative aconitate hydratase
SPAC222.08c glutamine aminotransferase subunit
gpd2 glycerol-3-phosphate dehydrogenase Gpd2
gly1 putative threonine aldolase Gly1
idh1 isocitrate dehydrogenase (NAD+) subunit 1 Idh1
SPAC17G8.06c putative dihydroxy-acid dehydratase
SPAC1F12.07 putative phosphoserine aminotransferase
SPAP8A3.07c putative phospho-2-dehydro-3-deoxyheptonate aldolase
idp1 putative isocitrate dehydrogenase Idp1
SPAC31G5.04 homoisocitrate dehydrogenase
snz1 pyridoxine biosynthesis protein
SPAC10F6.13c putative aspartate aminotransferase
SPAC328.09 putative 2-oxoadipate/2-oxoglutarate transporter
SPAC1002.12c putative succinate-semialdehyde dehydrogenase
dld1 dihydrolipoamide dehydrogenase Dld1
cit1 citrate synthase Cit1
leu2 putative 3-isopropylmalate dehydratase Leu2
SPAC56E4.03 putative aromatic aminotransferase
arg11 N-acetyl-gamma-glutamyl-phosphate reductase/acetylglutamate kinase
glt1 putative glutamate synthase Glt1
arg3 ornithine carbamoyltransferase Arg3
ilv5 putative acetohydroxyacid reductoisomerase
SPNCRNA.1358
Symbol Function*
CS citrate synthase
IDH2 isocitrate dehydrogenase (NADP(+)) 2
MDH2 malate dehydrogenase 2
GOT1 glutamic-oxaloacetic transaminase 1
SLC25A3 solute carrier family 25 member 3
IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
ATP5F1B ATP synthase F1 subunit beta
BCKDK branched chain keto acid dehydrogenase kinase
GOT2 glutamic-oxaloacetic transaminase 2
IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
ACO2 aconitase 2
ATP5F1A ATP synthase F1 subunit alpha
IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma


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