GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

106 hsa genes in this database.
103 mmu genes in this database.
103 rno genes in this database.
8 gga genes in this database.
15 dre genes in this database.
3 dme genes in this database.
2 cel genes in this database.
6 cfa genes in this database.

[QuickGO]

term: negative regulation of extrinsic apoptotic signaling pathway
goid: GO:2001237


Shaded genes do not have GeneChip data. The output was limited up to 100 for each of species.
Species Symbol Gene
coexpression
Locus
page
Full name* Entrez Gene ID Evidence*
hsa ACVR1 activin A receptor type 1 90 IMP
hsa AKT1 AKT serine/threonine kinase 1 207
hsa FAS Fas cell surface death receptor 355
hsa FASLG Fas ligand 356
hsa AR androgen receptor 367 IDA
hsa BCL2 BCL2 apoptosis regulator 596
hsa BCL2L1 BCL2 like 1 598
hsa BMP4 bone morphogenetic protein 4 652 ISS
hsa BMP5 bone morphogenetic protein 5 653
hsa BRCA1 BRCA1 DNA repair associated 672
hsa CASP8 caspase 8 841
hsa COL2A1 collagen type II alpha 1 chain 1280
hsa CSF2 colony stimulating factor 2 1437
hsa CTNNA1 catenin alpha 1 1495
hsa DDX3X DEAD-box helicase 3 X-linked 1654
hsa CTTN cortactin 2017 IEA
hsa EYA4 EYA transcriptional coactivator and phosphatase 4 2070
hsa EYA1 EYA transcriptional coactivator and phosphatase 1 2138
hsa EYA2 EYA transcriptional coactivator and phosphatase 2 2139
hsa EYA3 EYA transcriptional coactivator and phosphatase 3 2140
hsa FGA fibrinogen alpha chain 2243
hsa FGB fibrinogen beta chain 2244
hsa FGF10 fibroblast growth factor 10 2255
hsa FGG fibrinogen gamma chain 2266
hsa FYN FYN proto-oncogene, Src family tyrosine kinase 2534
hsa IFI6 interferon alpha inducible protein 6 2537
hsa GATA1 GATA binding protein 1 2623
hsa GDNF glial cell derived neurotrophic factor 2668
hsa GCLC glutamate-cysteine ligase catalytic subunit 2729 IEA
hsa GCLM glutamate-cysteine ligase modifier subunit 2730 IEA
hsa GPX1 glutathione peroxidase 1 2876
hsa GSK3B glycogen synthase kinase 3 beta 2932
hsa GSTP1 glutathione S-transferase pi 1 2950 IDA
hsa HTT huntingtin 3064 IMP
hsa HGF hepatocyte growth factor 3082
hsa HMGB2 high mobility group box 2 3148
hsa HMOX1 heme oxygenase 1 3162
hsa HSPA1A heat shock protein family A (Hsp70) member 1A 3303
hsa HSPA1B heat shock protein family A (Hsp70) member 1B 3304
hsa ICAM1 intercellular adhesion molecule 1 3383
hsa IGF1 insulin like growth factor 1 3479 IDA
hsa IL1A interleukin 1 alpha 3552
hsa IL1B interleukin 1 beta 3553
hsa IL4 interleukin 4 3565 IBA
hsa IL7 interleukin 7 3574
hsa ITGA6 integrin subunit alpha 6 3655 IMP
hsa ITGAV integrin subunit alpha V 3685 IMP
hsa LGALS3 galectin 3 3958 IBA,IDA
hsa LMNA lamin A/C 4000 IEA
hsa MCL1 MCL1 apoptosis regulator, BCL2 family member 4170
hsa NOS3 nitric oxide synthase 3 4846
hsa SERPINE1 serpin family E member 1 5054
hsa PF4 platelet factor 4 5196
hsa MAPK7 mitogen-activated protein kinase 7 5598
hsa MAP2K5 mitogen-activated protein kinase kinase 5 5607
hsa RAF1 Raf-1 proto-oncogene, serine/threonine kinase 5894
hsa RELA RELA proto-oncogene, NF-kB subunit 5970 IMP
hsa CX3CL1 C-X3-C motif chemokine ligand 1 6376
hsa SFRP2 secreted frizzled related protein 2 6423
hsa SIAH2 siah E3 ubiquitin protein ligase 2 6478 IMP
hsa SNAI2 snail family transcriptional repressor 2 6591
hsa SRC SRC proto-oncogene, non-receptor tyrosine kinase 6714 IBA,IMP
hsa TCF7L2 transcription factor 7 like 2 6934 ISS
hsa PRDX2 peroxiredoxin 2 7001
hsa TERT telomerase reverse transcriptase 7015
hsa TGFBR1 transforming growth factor beta receptor 1 7046 IMP
hsa THBS1 thrombospondin 1 7057 TAS
hsa TNF tumor necrosis factor 7124
hsa TNFAIP3 TNF alpha induced protein 3 7128
hsa TRAF2 TNF receptor associated factor 2 7186
hsa SCG2 secretogranin II 7857 IDA
hsa PEA15 proliferation and apoptosis adaptor protein 15 8682
hsa TRADD TNFRSF1A associated via death domain 8717
hsa RIPK1 receptor interacting serine/threonine kinase 1 8737 IMP
hsa TNFSF10 TNF superfamily member 10 8743
hsa FADD Fas associated via death domain 8772
hsa TNFRSF10B TNF receptor superfamily member 10b 8795
hsa TNFRSF10A TNF receptor superfamily member 10a 8797
hsa NRP1 neuropilin 1 8829 IEA
hsa CFLAR CASP8 and FADD like apoptosis regulator 8837 IDA,IMP
hsa NOL3 nucleolar protein 3 8996 IDA
hsa ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 9181
hsa RB1CC1 RB1 inducible coiled-coil 1 9821 IEA
hsa PSME3 proteasome activator subunit 3 10197 IDA
hsa YAP1 Yes1 associated transcriptional regulator 10413 IEA
hsa ZMYND11 zinc finger MYND-type containing 11 10771 IMP
hsa PARK7 Parkinsonism associated deglycase 11315 IMP
hsa FAIM2 Fas apoptotic inhibitory molecule 2 23017
hsa IL19 interleukin 19 29949 IEA
hsa ZC3HC1 zinc finger C3HC-type containing 1 51530
hsa PHIP pleckstrin homology domain interacting protein 55023 IDA
hsa FAIM Fas apoptotic inhibitory molecule 55179
hsa STRADB STE20 related adaptor beta 55437
hsa PAK5 p21 (RAC1) activated kinase 5 57144 IEA
hsa BIRC6 baculoviral IAP repeat containing 6 57448 IMP
hsa SH3RF1 SH3 domain containing ring finger 1 57630 IMP
hsa TMBIM1 transmembrane BAX inhibitor motif containing 1 64114
hsa RNF34 ring finger protein 34 80196
hsa ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein 85450
hsa SCRT2 scratch family transcriptional repressor 2 85508
mmu Acvr1 activin A receptor, type 1 11477 ISO
mmu Ar androgen receptor 11835 ISO
mmu Bcl2 B cell leukemia/lymphoma 2 12043
mmu Bcl2l1 BCL2-like 1 12048
mmu Bcl2l10 Bcl2-like 10 12049
mmu Bmp4 bone morphogenetic protein 4 12159 IMP
mmu Brca1 breast cancer 1, early onset 12189
mmu Birc6 baculoviral IAP repeat-containing 6 12211 ISO
mmu Ctnna1 catenin (cadherin associated protein), alpha 1 12385
mmu Rb1cc1 RB1-inducible coiled-coil 1 12421 IMP
mmu Cflar CASP8 and FADD-like apoptosis regulator 12633 IGI,ISO
mmu Col2a1 collagen, type II, alpha 1 12824
mmu Csf2 colony stimulating factor 2 (granulocyte-macrophage) 12981
mmu Cttn cortactin 13043 IGI
mmu Cx3cr1 chemokine (C-X3-C motif) receptor 1 13051
mmu Dab2 disabled 2, mitogen-responsive phosphoprotein 13132 IMP
mmu Ddx3x DEAD box helicase 3, X-linked 13205
mmu Eya1 EYA transcriptional coactivator and phosphatase 1 14048
mmu Eya2 EYA transcriptional coactivator and phosphatase 2 14049
mmu Eya3 EYA transcriptional coactivator and phosphatase 3 14050
mmu Eya4 EYA transcriptional coactivator and phosphatase 4 14051
mmu Fga fibrinogen alpha chain 14161
mmu Fgf10 fibroblast growth factor 10 14165
mmu Fyn Fyn proto-oncogene 14360
mmu Gas1 growth arrest specific 1 14451
mmu Gata1 GATA binding protein 1 14460
mmu Gdnf glial cell line derived neurotrophic factor 14573
mmu Gclc glutamate-cysteine ligase, catalytic subunit 14629 IGI
mmu Gclm glutamate-cysteine ligase, modifier subunit 14630 IGI
mmu Gpx1 glutathione peroxidase 1 14775
mmu Gstp2 glutathione S-transferase, pi 2 14869 ISO
mmu Gstp1 glutathione S-transferase, pi 1 14870 ISO
mmu Htt huntingtin 15194 ISO
mmu Hgf hepatocyte growth factor 15234
mmu Hmox1 heme oxygenase 1 15368
mmu Icam1 intercellular adhesion molecule 1 15894
mmu Igf1 insulin-like growth factor 1 16000 ISO
mmu Il1b interleukin 1 beta 16176
mmu Il4 interleukin 4 16189 IBA,IDA
mmu Il7 interleukin 7 16196 IDA
mmu Itga6 integrin alpha 6 16403 ISO
mmu Itgav integrin alpha V 16410 ISO
mmu Lgals3 lectin, galactose binding, soluble 3 16854 IBA,ISO
mmu Lmna lamin A 16905 IMP
mmu Mcl1 myeloid cell leukemia sequence 1 17210
mmu Nrp1 neuropilin 1 18186 IMP
mmu Pea15a proliferation and apoptosis adaptor protein 15A 18611
mmu Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 18787
mmu Psen2 presenilin 2 19165
mmu Psme3 proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) 19192 ISO
mmu Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 19697 IDA,ISO
mmu Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 19766 IGI,ISO
mmu Scg2 secretogranin II 20254 ISO
mmu Cx3cl1 chemokine (C-X3-C motif) ligand 1 20312
mmu Sfrp2 secreted frizzled-related protein 2 20319
mmu Siah2 siah E3 ubiquitin protein ligase 2 20439 ISO
mmu Snai2 snail family zinc finger 2 20583
mmu Src Rous sarcoma oncogene 20779 IBA,ISO
mmu Prdx2 peroxiredoxin 2 21672 IMP
mmu Tert telomerase reverse transcriptase 21752
mmu Tgfbr1 transforming growth factor, beta receptor I 21812 ISO
mmu Tnf tumor necrosis factor 21926
mmu Tnfaip3 tumor necrosis factor, alpha-induced protein 3 21929
mmu Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 22163 IMP
mmu Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 22164 IC
mmu Vegfa vascular endothelial growth factor A 22339 IDA
mmu Yap1 yes-associated protein 1 22601 IGI
mmu Faim Fas apoptotic inhibitory molecule 23873
mmu Map2k5 mitogen-activated protein kinase kinase 5 23938
mmu Mapk7 mitogen-activated protein kinase 7 23939
mmu Gsk3b glycogen synthase kinase 3 beta 56637
mmu Park7 Parkinson disease (autosomal recessive, early onset) 7 57320 ISO
mmu Sh3rf1 SH3 domain containing ring finger 1 59009 ISO
mmu Zmynd11 zinc finger, MYND domain containing 11 66505 ISO
mmu Rffl ring finger and FYVE like domain containing protein 67338
mmu Fcmr Fc fragment of IgM receptor 69169 IDA
mmu Dapk1 death associated protein kinase 1 69635
mmu Tmbim1 transmembrane BAX inhibitor motif containing 1 69660
mmu Faim2 Fas apoptotic inhibitory molecule 2 72393
mmu Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 72508 IMP
mmu Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) 78688 ISO
mmu Tnfrsf23 tumor necrosis factor receptor superfamily, member 23 79201
mmu Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 79202
mmu Rnf34 ring finger protein 34 80751
mmu Phip pleckstrin homology domain interacting protein 83946 ISO
mmu Hmgb2 high mobility group box 2 97165
mmu Fgg fibrinogen gamma chain 99571
mmu Unc5b unc-5 netrin receptor B 107449
mmu Fgb fibrinogen beta chain 110135
mmu Raf1 v-raf-leukemia viral oncogene 1 110157
mmu D1Pas1 DNA segment, Chr 1, Pasteur Institute 1 110957
mmu Sgk3 serum/glucocorticoid regulated kinase 3 170755
mmu Sgms1 sphingomyelin synthase 1 208449 IDA
mmu Nrg1 neuregulin 1 211323
mmu Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 216439
mmu Stradb STE20-related kinase adaptor beta 227154
mmu Zc3hc1 zinc finger, C3HC type 1 232679
mmu Peli3 pellino 3 240518 IMP,ISO
mmu Pak5 p21 (RAC1) activated kinase 5 241656 IDA
mmu Il19 interleukin 19 329244 IDA
rno Ar androgen receptor 24208 IEA,ISO,ISS
rno Bcl2 BCL2, apoptosis regulator 24224
rno Fgb fibrinogen beta chain 24366
rno Fgg fibrinogen gamma chain 24367
rno Gpx1 glutathione peroxidase 1 24404
rno Gstp1 glutathione S-transferase pi 1 24426 ISO
rno Hgf hepatocyte growth factor 24446
rno Hmox1 heme oxygenase 1 24451
rno Hspa1a heat shock protein family A (Hsp70) member 1A 24472
rno Igf1 insulin-like growth factor 1 24482 IDA,IEA,ISO
rno Il1b interleukin 1 beta 24494
rno Serpine1 serpin family E member 1 24617
rno Raf1 Raf-1 proto-oncogene, serine/threonine kinase 24703
rno Scg2 secretogranin II 24765 IEA,ISO
rno Tnf tumor necrosis factor 24835
rno Bcl2l1 Bcl2-like 1 24888
rno Fyn FYN proto-oncogene, Src family tyrosine kinase 25150
rno Gata1 GATA binding protein 1 25172
rno Gclc glutamate-cysteine ligase, catalytic subunit 25283 ISO
rno Bmp4 bone morphogenetic protein 4 25296 IEA,ISO
rno Col2a1 collagen type II alpha 1 chain 25412
rno Fgf10 fibroblast growth factor 10 25443
rno Gdnf glial cell derived neurotrophic factor 25453
rno Icam1 intercellular adhesion molecule 1 25464
rno Snai2 snail family transcriptional repressor 2 25554
rno Tnfrsf4 TNF receptor superfamily member 4 25572 ISO
rno Il7 interleukin 7 25647 ISO
rno Prdx2 peroxiredoxin 2 29338 ISO
rno Hmgb2 high mobility group box 2 29395
rno Htt huntingtin 29424 IEA,ISO
rno Map2k5 mitogen activated protein kinase kinase 5 29568
rno Tgfbr1 transforming growth factor, beta receptor 1 29591 ISO
rno Gclm glutamate cysteine ligase, modifier subunit 29739 ISO
rno Lmna lamin A/C 60374 IEA,ISO
rno Mcl1 MCL1 apoptosis regulator, BCL2 family member 60430
rno Cttn cortactin 60465 ISO
rno Unc5b unc-5 netrin receptor B 60630
rno Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 65218
rno Dab2 DAB adaptor protein 2 79128 ISO
rno Acvr1 activin A receptor type 1 79558 IEA,ISO
rno Psen2 presenilin 2 81751
rno Lgals3 galectin 3 83781 IBA,IEA,ISO
rno Vegfa vascular endothelial growth factor A 83785 ISO
rno Src SRC proto-oncogene, non-receptor tyrosine kinase 83805 IBA,ISO
rno Rps6kb1 ribosomal protein S6 kinase B1 83840 ISO
rno Gsk3b glycogen synthase kinase 3 beta 84027
rno Nol3 nucleolar protein 3 85383 IEA,ISO
rno Cx3cl1 C-X3-C motif chemokine ligand 1 89808
rno Nrg1 neuregulin 1 112400
rno Mapk7 mitogen-activated protein kinase 7 114509
rno Itga6 integrin subunit alpha 6 114517 ISO
rno Bcl2l10 BCL2 like 10 114552
rno Csf2 colony stimulating factor 2 116630
rno Cflar CASP8 and FADD-like apoptosis regulator 117279 ISO,ISO
rno Park7 Parkinsonism associated deglycase 117287 ISO,ISS
rno Siah2 siah E3 ubiquitin protein ligase 2 140593 ISO
rno Faim Fas apoptotic inhibitory molecule 140930
rno Eya2 EYA transcriptional coactivator and phosphatase 2 156826
rno Cx3cr1 C-X3-C motif chemokine receptor 1 171056
rno Sgk3 serum/glucocorticoid regulated kinase family, member 3 171498
rno Faim2 Fas apoptotic inhibitory molecule 2 246274
rno Nrp1 neuropilin 1 246331 ISO
rno Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 282844
rno Rnf34 ring finger protein 34 282845
rno Il4 interleukin 4 287287 IBA,ISO
rno Psme3 proteasome activator subunit 3 287716 ISO
rno Zmynd11 zinc finger, MYND-type containing 11 291259 ISO
rno Eya4 EYA transcriptional coactivator and phosphatase 4 292172
rno Itgav integrin subunit alpha V 296456 ISO
rno Zc3hc1 zinc finger, C3HC-type containing 1 296957
rno Tert telomerase reverse transcriptase 301965
rno Sh3rf1 SH3 domain containing ring finger 1 306417 ISO
rno Dapk1 death associated protein kinase 1 306722
rno Ripk1 receptor interacting serine/threonine kinase 1 306886 ISO,ISO
rno Ctnna1 catenin alpha 1 307505
rno Peli3 pellino E3 ubiquitin protein ligase family member 3 309157 ISO
rno Rela RELA proto-oncogene, NF-kB subunit 309165 ISO,ISO
rno Sfrp2 secreted frizzled-related protein 2 310552
rno Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 310635
rno Pak5 p21 (RAC1) activated kinase 5 311450 ISO
rno Rb1cc1 RB1-inducible coiled-coil 1 312927 ISO
rno Eya3 EYA transcriptional coactivator and phosphatase 3 313027
rno Birc6 baculoviral IAP repeat-containing 6 313876 ISO
rno Phip pleckstrin homology domain interacting protein 315843 ISO
rno Tmbim1 transmembrane BAX inhibitor motif containing 1 316516
rno Ddx3x DEAD-box helicase 3, X-linked 317335
rno Sgms1 sphingomyelin synthase 1 353229 ISO
rno Pf4 platelet factor 4 360918
rno Fga fibrinogen alpha chain 361969
rno Yap1 Yes1 associated transcriptional regulator 363014 ISO
rno Pea15 proliferation and apoptosis adaptor protein 15 364052
rno Brca1 BRCA1, DNA repair associated 497672
rno Gfral GDNF family receptor alpha like 501023
rno Stradb STE20 related adaptor beta 501146
rno Eya1 EYA transcriptional coactivator and phosphatase 1 502935
rno Fcmr Fc fragment of IgM receptor 548326 ISO
rno Tcf7l2 transcription factor 7 like 2 679869 IMP
rno Il19 interleukin 19 681145 ISO
rno Tnfaip3 TNF alpha induced protein 3 683206
rno Gas1 growth arrest-specific 1 683470
gga ATVR1 serine/threonine-protein kinase receptor 395246 ISA
gga EYA4 EYA transcriptional coactivator and phosphatase 4 395716
gga EYA3 EYA transcriptional coactivator and phosphatase 3 395717
gga EYA1 EYA transcriptional coactivator and phosphatase 1 395718
gga ITGA6 integrin subunit alpha 6 396226 IEA
gga RAF1 Raf-1 proto-oncogene, serine/threonine kinase 396245
gga SRC SRC proto-oncogene, non-receptor tyrosine kinase 396442 IBA
gga IGF1 insulin like growth factor 1 418090 IEA
dre eya1 EYA transcriptional coactivator and phosphatase 1 30436
dre src v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog 325084 IBA
dre lgals3b lectin, galactoside binding soluble 3b 325599 IBA
dre rnf34a ring finger protein 34a 334203
dre cflara CASP8 and FADD-like apoptosis regulator a 373114
dre rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 405832
dre faimb Fas apoptotic inhibitory molecule b 436668
dre faima Fas apoptotic inhibitory molecule a 436856
dre eya2 EYA transcriptional coactivator and phosphatase 2 447819
dre snx13 sorting nexin 13 503733 IMP
dre eya4 EYA transcriptional coactivator and phosphatase 4 541552
dre lgals3a lectin, galactoside binding soluble 3a 557373 IBA
dre rnf34b ring finger protein 34b 568879
dre eya3 EYA transcriptional coactivator and phosphatase 3 571385
dre zgc:171740 zgc:171740 795694
dme eya eyes absent 33916
dme CG17019 uncharacterized protein 36425
dme CG10257 uncharacterized protein 36671
cel eya-1 Eyes absent homolog 1 173293
cel C44B11.1 Uncharacterized protein 175421
cfa HGF hepatocyte growth factor 403441
cfa ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 403498
cfa AR androgen receptor 403588 ISS
cfa TNF tumor necrosis factor 403922
cfa CSF2 colony stimulating factor 2 403923
cfa SFRP2 secreted frizzled related protein 2 475471


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