GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

124 hsa genes in this database.
70 mmu genes in this database.
67 rno genes in this database.
6 gga genes in this database.
10 dre genes in this database.
15 dme genes in this database.
3 cel genes in this database.
3 cfa genes in this database.
7 sce genes in this database.
13 spo genes in this database.

[QuickGO]

term: negative regulation of G1/S transition of mitotic cell cycle
goid: GO:2000134


Shaded genes do not have GeneChip data. The output was limited up to 100 for each of species.
Species Symbol Gene
coexpression
Locus
page
Full name* Entrez Gene ID Evidence*
hsa APC APC regulator of WNT signaling pathway 324 IMP
hsa ATM ATM serine/threonine kinase 472
hsa BAX BCL2 associated X, apoptosis regulator 581
hsa CCND1 cyclin D1 595
hsa BCL2 BCL2 apoptosis regulator 596 IEA
hsa CASP2 caspase 2 835
hsa CCNB1 cyclin B1 891
hsa CDK1 cyclin dependent kinase 1 983
hsa CDC25C cell division cycle 25C 995
hsa CDK2 cyclin dependent kinase 2 1017
hsa CDK4 cyclin dependent kinase 4 1019 TAS
hsa CDK6 cyclin dependent kinase 6 1021 TAS
hsa CDKN1A cyclin dependent kinase inhibitor 1A 1026 IGI
hsa CDKN1B cyclin dependent kinase inhibitor 1B 1027
hsa CDKN2A cyclin dependent kinase inhibitor 2A 1029 TAS
hsa CDKN2B cyclin dependent kinase inhibitor 2B 1030 TAS
hsa CDKN2C cyclin dependent kinase inhibitor 2C 1031 TAS
hsa CDKN2D cyclin dependent kinase inhibitor 2D 1032 TAS
hsa PLK3 polo like kinase 3 1263
hsa GADD45A growth arrest and DNA damage inducible alpha 1647
hsa DLG1 discs large MAGUK scaffold protein 1 1739 IMP
hsa ARID3A AT-rich interaction domain 3A 1820
hsa E2F1 E2F transcription factor 1 1869
hsa E2F4 E2F transcription factor 4 1874
hsa EP300 E1A binding protein p300 2033
hsa EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2146 IEA
hsa FHL1 four and a half LIM domains 1 2273 IDA
hsa GML glycosylphosphatidylinositol anchored molecule like 2765
hsa SFN stratifin 2810
hsa PRMT2 protein arginine methyltransferase 2 3275 ISS
hsa PRMT1 protein arginine methyltransferase 1 3276
hsa MDM2 MDM2 proto-oncogene 4193
hsa MDM4 MDM4 regulator of p53 4194
hsa MUC1 mucin 1, cell surface associated 4582
hsa CNOT2 CCR4-NOT transcription complex subunit 2 4848
hsa CNOT3 CCR4-NOT transcription complex subunit 3 4849
hsa CNOT4 CCR4-NOT transcription complex subunit 4 4850
hsa PCNA proliferating cell nuclear antigen 5111
hsa PKD2 polycystin 2, transient receptor potential cation channel 5311 IMP
hsa PLAGL1 PLAG1 like zinc finger 1 5325
hsa PML PML nuclear body scaffold 5371
hsa PRKDC protein kinase, DNA-activated, catalytic subunit 5591
hsa PTEN phosphatase and tensin homolog 5728 IDA
hsa RB1 RB transcriptional corepressor 1 5925 IBA,TAS
hsa RBL1 RB transcriptional corepressor like 1 5933 IBA
hsa RBL2 RB transcriptional corepressor like 2 5934 IBA
hsa RPA2 replication protein A2 6118
hsa RPL26 ribosomal protein L26 6154
hsa CCL2 C-C motif chemokine ligand 2 6347 IMP
hsa SOX4 SRY-box transcription factor 4 6659
hsa AURKA aurora kinase A 6790
hsa TFDP1 transcription factor Dp-1 7027
hsa TFDP2 transcription factor Dp-2 7029
hsa TP53 tumor protein p53 7157
hsa WEE1 WEE1 G2 checkpoint kinase 7465 TAS
hsa BTG2 BTG anti-proliferation factor 2 7832
hsa GFI1B growth factor independent 1B transcriptional repressor 8328 TAS
hsa CRADD CASP2 and RIPK1 domain containing adaptor with death domain 8738
hsa CNOT9 CCR4-NOT transcription complex subunit 9 9125
hsa KLF4 Kruppel like factor 4 9314 IDA
hsa CNOT8 CCR4-NOT transcription complex subunit 8 9337
hsa CTDSP2 CTD small phosphatase 2 10106 IEA
hsa CTDSPL CTD small phosphatase like 10217 IEA
hsa CDK2AP2 cyclin dependent kinase 2 associated protein 2 10263 IMP
hsa GPNMB glycoprotein nmb 10457 IDA
hsa CARM1 coactivator associated arginine methyltransferase 1 10498
hsa PLK2 polo like kinase 2 10769
hsa FAM107A family with sequence similarity 107 member A 11170 IMP
hsa CHEK2 checkpoint kinase 2 11200
hsa TREX1 three prime repair exonuclease 1 11277
hsa CNOT1 CCR4-NOT transcription complex subunit 1 23019
hsa MYO16 myosin XVI 23026 IBA,ISS
hsa FBXO7 F-box protein 7 25793 IEA
hsa CNOT10 CCR4-NOT transcription complex subunit 10 25904
hsa ZNF385A zinc finger protein 385A 25946
hsa KANK2 KN motif and ankyrin repeat domains 2 25959 IBA,IDA
hsa GIGYF2 GRB10 interacting GYF protein 2 26058
hsa RGCC regulator of cell cycle 28984
hsa BRD7 bromodomain containing 7 29117 IDA
hsa CNOT7 CCR4-NOT transcription complex subunit 7 29883
hsa RPS27L ribosomal protein S27 like 51065
hsa TFDP3 transcription factor Dp family member 3 51270 IDA
hsa WAC WW domain containing adaptor with coiled-coil 51322
hsa DACT1 dishevelled binding antagonist of beta catenin 1 51339 IDA
hsa TRIAP1 TP53 regulated inhibitor of apoptosis 1 51499
hsa GTSE1 G2 and S-phase expressed 1 51512
hsa RFWD3 ring finger and WD repeat domain 3 55159
hsa PIDD1 p53-induced death domain protein 1 55367
hsa CNOT11 CCR4-NOT transcription complex subunit 11 55571
hsa PCBP4 poly(rC) binding protein 4 57060
hsa GJC2 gap junction protein gamma 2 57165 IEA
hsa CNOT6 CCR4-NOT transcription complex subunit 6 57472
hsa CTDSP1 CTD small phosphatase 1 58190 IEA
hsa ZNF655 zinc finger protein 655 79027 IDA
hsa CDC73 cell division cycle 73 79577 IDA
hsa E2F8 E2F transcription factor 8 79733
hsa FBXO31 F-box protein 31 79791
hsa JADE1 jade family PHD finger 1 79960 IDA
hsa TNKS1BP1 tankyrase 1 binding protein 1 85456
hsa SLFN11 schlafen family member 11 91607 IMP
mmu Apc APC, WNT signaling pathway regulator 11789 ISO
mmu Bcl2 B cell leukemia/lymphoma 2 12043 IDA,IMP
mmu Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 12298 ISO
mmu Casp2 caspase 2 12366
mmu Ccnd1 cyclin D1 12443
mmu Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 12575 ISO
mmu Cdkn2b cyclin dependent kinase inhibitor 2B 12579 IMP
mmu Plk3 polo like kinase 3 12795
mmu Cradd CASP2 and RIPK1 domain containing adaptor with death domain 12905
mmu Dlg1 discs large MAGUK scaffold protein 1 13383 ISO
mmu Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit 14056 IMP
mmu Fhl1 four and a half LIM domains 1 14199 ISO
mmu Fhl4 four and a half LIM domains 4 14202 ISO
mmu Haspin histone H3 associated protein kinase 14841 IDA
mmu Prmt2 protein arginine N-methyltransferase 2 15468 IMP
mmu Klf4 Kruppel-like factor 4 (gut) 16600 ISO
mmu Mdm2 transformed mouse 3T3 cell double minute 2 17246
mmu Muc1 mucin 1, transmembrane 17829
mmu Pkd2 polycystin 2, transient receptor potential cation channel 18764 ISO
mmu Pml promyelocytic leukemia 18854
mmu Ppp2r3d protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta 19054 IDA
mmu Prkdc protein kinase, DNA activated, catalytic polypeptide 19090
mmu Pten phosphatase and tensin homolog 19211 ISO
mmu Rb1 RB transcriptional corepressor 1 19645 IBA,IMP
mmu Rbl1 RB transcriptional corepressor like 1 19650 IBA
mmu Rbl2 RB transcriptional corepressor like 2 19651 IBA
mmu Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 19766 IMP
mmu Rpa2 replication protein A2 19891
mmu Rpl26 ribosomal protein L26 19941
mmu Ccl12 chemokine (C-C motif) ligand 12 20293 ISO
mmu Ccl2 chemokine (C-C motif) ligand 2 20296 ISO
mmu Slfn1 schlafen 1 20555 IDA,IGI
mmu Sox4 SRY (sex determining region Y)-box 4 20677
mmu Trex1 three prime repair exonuclease 1 22040
mmu Trp53 transformation related protein 53 22059
mmu Prap1 proline-rich acidic protein 1 22264
mmu Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma 26931
mmu Brd7 bromodomain containing 7 26992 ISO
mmu Cdk2ap2 CDK2-associated protein 2 52004 ISO
mmu Ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 52468 IDA
mmu E2f7 E2F transcription factor 7 52679 IDA
mmu Rbm38 RNA binding motif protein 38 56190
mmu Pidd1 p53 induced death domain protein 1 57913
mmu Dact1 dishevelled-binding antagonist of beta-catenin 1 59036 ISO
mmu Rps27l ribosomal protein S27-like 67941
mmu Nacc2 nucleus accumbens associated 2, BEN and BTB (POZ) domain containing 67991
mmu Ctdspl CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 69274 IDA
mmu Fbxo7 F-box protein 7 69754 IMP
mmu Zfp655 zinc finger protein 655 72611 ISO
mmu Fbxo31 F-box protein 31 76454
mmu Gpnmb glycoprotein (transmembrane) nmb 93695 ISO
mmu Dgkz diacylglycerol kinase zeta 104418
mmu Gjc2 gap junction protein, gamma 2 118454 ISO
mmu Sde2 SDE2 telomere maintenance homolog (S. pombe) 208768
mmu Cdc73 cell division cycle 73, Paf1/RNA polymerase II complex component 214498 ISO
mmu Plk5 polo like kinase 5 216166
mmu Wac WW domain containing adaptor with coiled-coil 225131
mmu Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 227292 IDA
mmu Gigyf2 GRB10 interacting GYF protein 2 227331
mmu Dcun1d3 DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) 233805 ISO
mmu Rfwd3 ring finger and WD repeat domain 3 234736
mmu Kank2 KN motif and ankyrin repeat domains 2 235041 IBA,ISO
mmu Zc3h12d zinc finger CCCH type containing 12D 237256 ISO
mmu Btn2a2 butyrophilin, subfamily 2, member A2 238555 IDA
mmu Myo16 myosin XVI 244281 IBA,ISO
mmu Fam107a family with sequence similarity 107, member A 268709 ISO
mmu Jade1 jade family PHD finger 1 269424 ISO
mmu Mir26a-1 microRNA 26a-1 387218 IDA
mmu Mir26b microRNA 26b 387219 IDA
mmu Mir26a-2 microRNA 26a-2 723962 IDA
rno Apc APC regulator of WNT signaling pathway 24205 IEA,ISO
rno Bcl2 BCL2, apoptosis regulator 24224 IEA,ISO
rno Muc1 mucin 1, cell surface associated 24571
rno Rb1 RB transcriptional corepressor 1 24708 IBA,IEA,ISO
rno Ccl2 C-C motif chemokine ligand 2 24770 ISO
rno Tp53 tumor protein p53 24842
rno Cdkn2b cyclin-dependent kinase inhibitor 2B 25164 IEA,ISO
rno Fhl1 four and a half LIM domains 1 25177 ISO
rno Dlg1 discs large MAGUK scaffold protein 1 25252 IEA,ISO,ISS
rno Pten phosphatase and tensin homolog 50557 ISO
rno Ccnd1 cyclin D1 58919
rno Plk3 polo-like kinase 3 58936
rno Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 58942 IDA
rno Rpa2 replication protein A2 59102
rno Prap1 proline-rich acidic protein 1 60574
rno Casp2 caspase 2 64314
rno Rbl2 RB transcriptional corepressor like 2 81758 IBA
rno Dgkz diacylglycerol kinase zeta 81821
rno Gpnmb glycoprotein nmb 113955 ISO
rno Klf4 Kruppel like factor 4 114505 ISO
rno Cdkn1a cyclin-dependent kinase inhibitor 1A 114851 ISO
rno Myo16 myosin XVI 192253 IBA,IDA
rno Rpl26 ribosomal protein L26 287417
rno Sde2 SDE2 telomere maintenance homolog 289315
rno Pidd1 p53-induced death domain protein 1 293625
rno Nacc2 NACC family member 2 296583
rno Ctdspl CTD small phosphatase like 301056 ISO
rno Slfn13 schlafen family member 13 303378 ISO
rno Cdc73 cell division cycle 73 304832 IEA,ISO,ISS
rno Ripk1 receptor interacting serine/threonine kinase 1 306886 ISO
rno Btn2a2 butyrophilin, subfamily 2, member A2 306957 ISO
rno Wac WW domain containing adaptor with coiled-coil 307029
rno Zc3h12d zinc finger CCCH type containing 12D 308266 ISO
rno Dcun1d3 defective in cullin neddylation 1 domain containing 3 309035 ISO,ISS
rno Jade1 jade family PHD finger 1 310352 ISO
rno Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit 312299 ISO
rno Plk5 polo-like kinase 5 314627
rno Cradd CASP2 and RIPK1 domain containing adaptor with death domain 314756
rno E2f7 E2F transcription factor 7 314818 ISO,ISS
rno Mdm2 MDM2 proto-oncogene 314856
rno Pml PML nuclear body scaffold 315713
rno Prkdc protein kinase, DNA-activated, catalytic subunit 360748
rno Zfp655 zinc finger protein 655 360764 ISO,ISS
rno Fam107a family with sequence similarity 107, member A 361018 IEA,ISO,ISS
rno Brd7 bromodomain containing 7 361374 ISO
rno Ctdsp1 CTD small phosphatase 1 363249 ISO
rno Sox4 SRY-box transcription factor 4 364712
rno Rbm38 RNA binding motif protein 38 366262
rno Fbxo7 F-box protein 7 366854 ISO
rno Gjc2 gap junction protein, gamma 2 497913 IMP
rno Pkd2 polycystin 2, transient receptor potential cation channel 498328 ISO
rno Fbxo31 F-box protein 31 498959
rno Prmt2 protein arginine methyltransferase 2 499420 ISO
rno Dact1 dishevelled-binding antagonist of beta-catenin 1 500666 ISO
rno Rbl1 RB transcriptional corepressor like 1 680111 IBA
rno Rps27l ribosomal protein S27-like 681429
rno Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta 682033 ISO
rno Haspin histone H3 associated protein kinase 687827 ISO
rno Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 688405 ISO
rno Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma 691318
rno Trex1 three prime repair exonuclease 1 100049583
rno Mir26b microRNA 26b 100314229 ISO
rno Mir26a microRNA 26a 100314290 ISO
rno Kank2 KN motif and ankyrin repeat domains 2 100361376 IBA,ISO
rno Gigyf2 GRB10 interacting GYF protein 2 100362458
rno Ctdsp2 CTD small phosphatase 2 100365370 ISO
rno Rfwd3 ring finger and WD repeat domain 3 103690025
gga RB1 RB transcriptional corepressor 1 386582 IBA
gga PRKDC protein kinase, DNA-activated, catalytic polypeptide 395376
gga BCL2 BCL2, apoptosis regulator 396282 IEA
gga CCND1 cyclin D1 396341
gga CTDSPL CTD small phosphatase like 408252 IEA
gga CDC73 cell division cycle 73 424356 ISS
dre ccnd1 cyclin D1 30222
dre dlg1a discs large MAGUK scaffold protein 1a 114446 ISS
dre plk3 polo-like kinase 3 (Drosophila) 334202
dre dlg1b discs large MAGUK scaffold protein 1b 497648 ISS
dre fbxo31 F-box protein 31 555190
dre e2f7 E2F transcription factor 7 567941 ISS
dre kank2 KN motif and ankyrin repeat domains 2 571549 IBA
dre rb1 retinoblastoma 1 777733 IBA
dre rbl1 retinoblastoma-like 1 (p107) 795522 IBA
dre rbl2 retinoblastoma-like 2 (p130) 100331892 IBA
dme Rbf Retinoblastoma-family protein 31027 IBA,IMP
dme CHES-1-like Checkpoint suppressor 1-like 31678
dme smo smoothened 33196 IMP
dme Mad Mothers against dpp 33529 IMP
dme Mnn1 Menin 1 33991
dme Sos Son of sevenless 34790 IMP
dme E2f2 E2F transcription factor 2 35381 IDA
dme dap dacapo 36001 IMP
dme Egfr Epidermal growth factor receptor 37455 IMP
dme brm brahma 39744 IGI
dme B52 B52 41670
dme tefu telomere fusion 41839 IGI
dme Rbf2 Retinoblastoma-family protein 2 41941 IBA,IDA
dme mor moira 41942 IGI
dme CycG Cyclin G 43724 IGI
cel lin-35 Retinoblastoma-like protein homolog lin-35 172249 IBA
cel cki-1 Cyclin-dependent kinase inhibitor 1 174260 IMP
cel dpl-1 Transcription factor dpl-1 174458
cfa PTEN phosphatase and tensin homolog 403832 IEA
cfa CCND1 cyclin D1 449028
cfa PRKDC protein kinase, DNA-activated, catalytic subunit 474176
sce BRE1 E3 ubiquitin-protein ligase BRE1 851485
sce RAD9 chromatin-binding protein RAD9 851803
sce DOT1 histone methyltransferase DOT1 852050
sce RAD6 E2 ubiquitin-conjugating protein RAD6 852822
sce RIE1 Rie1p 853165 IPI
sce ASH1 DNA-binding transcription repressor ASH1 853650
sce DDC1 Ddc1p 855907
spo wee1 protein kinase Wee1 2539123
spo par1 protein phosphatase regulatory subunit Par1 2539379
spo rum1 CDK inhibitor Rum1 2539640 IGI,IMP
spo cdc2 cyclin-dependent protein kinase Cdk1/Cdc2 2539869
spo SPBC2A9.07c zf-PARP type zinc finger protein 2540460 IMP
spo gcn2 eIF2 alpha kinase Gcn2 2540500
spo tsc1 hamartin 2541869 IMP
spo SPAC18G6.05c putative translation elongation regulator Gcn1 2542235
spo srw1 CDK inhibitor Srw1 2542824 IGI
spo tsc2 tuberin 2543339 IMP
spo cig2 G1/S-specific B-type cyclin Cig2 2543481
spo pas1 cyclin Pas1 3361406 IMP
spo lkh1 dual-specificity 3361532 IMP


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