GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

33 hsa genes in this database.
38 mmu genes in this database.
36 rno genes in this database.
1 gga genes in this database.
8 dre genes in this database.
5 dme genes in this database.
1 cel genes in this database.
1 sce genes in this database.
1 spo genes in this database.

[QuickGO]

term: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
goid: GO:0070059

Shaded genes do not have GeneChip data. The output was limited up to 100 for each of species.
Species Symbol Gene
coexpression		 Locus
page 		Full name* Entrez Gene ID Evidence*
hsa ATF4 activating transcription factor 4 468 ISS
hsa ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 487 IMP
hsa ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 489 IDA
hsa BAK1 BCL2 antagonist/killer 1 578 TAS
hsa BAX BCL2 associated X, apoptosis regulator 581 IMP,TAS
hsa BCL2 BCL2 apoptosis regulator 596 IDA
hsa CASP4 caspase 4 837 IMP
hsa CEBPB CCAAT enhancer binding protein beta 1051 TAS
hsa DDIT3 DNA damage inducible transcript 3 1649 IBA,IDA,IMP,TAS
hsa ERN1 endoplasmic reticulum to nucleus signaling 1 2081 IBA
hsa UBE2K ubiquitin conjugating enzyme E2 K 3093 IEA
hsa ITPR1 inositol 1,4,5-trisphosphate receptor type 1 3708 ISS
hsa MAP3K5 mitogen-activated protein kinase kinase kinase 5 4217 ISS
hsa PML PML nuclear body scaffold 5371 IEA
hsa TMBIM6 transmembrane BAX inhibitor motif containing 6 7009 IEA
hsa TP53 tumor protein p53 7157 IEA
hsa TRAF2 TNF receptor associated factor 2 7186 TAS
hsa BAG6 BAG cochaperone 6 7917 ISS
hsa TNFRSF10B TNF receptor superfamily member 10b 8795 IMP,TAS
hsa BRSK2 BR serine/threonine kinase 2 9024 IMP
hsa AIFM1 apoptosis inducing factor mitochondria associated 1 9131 ISS
hsa ERN2 endoplasmic reticulum to nucleus signaling 2 10595 IBA
hsa PPP1R15A protein phosphatase 1 regulatory subunit 15A 23645 TAS
hsa BBC3 BCL2 binding component 3 27113 IBA
hsa ERO1A endoplasmic reticulum oxidoreductase 1 alpha 30001 ISS
hsa DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 54431 IDA
hsa RNF186 ring finger protein 186 54546 IBA,IMP
hsa QRICH1 glutamine rich 1 54870 IMP
hsa TRIB3 tribbles pseudokinase 3 57761 IDA,TAS
hsa SELENOK selenoprotein K 58515 IMP
hsa CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 79094 IMP
hsa TMEM117 transmembrane protein 117 84216 IBA,IMP
hsa DAB2IP DAB2 interacting protein 153090 ISS
mmu Apaf1 apoptotic peptidase activating factor 1 11783 IMP
mmu Atf4 activating transcription factor 4 11911 IDA,IMP
mmu Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 11937 ISO
mmu Bak1 BCL2-antagonist/killer 1 12018 IGI
mmu Bax BCL2-associated X protein 12028 IGI,ISO
mmu Bcl2 B cell leukemia/lymphoma 2 12043 ISS
mmu Casp12 caspase 12 12364 IDA,IGI,IMP,TAS
mmu Casp3 caspase 3 12367 NAS
mmu Casp9 caspase 9 12371 NAS
mmu Cebpb CCAAT/enhancer binding protein (C/EBP), beta 12608 IMP
mmu Ddit3 DNA-damage inducible transcript 3 13198 IBA,IDA,IMP,IMP,ISO
mmu Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 13666 IMP
mmu Ins2 insulin II 16334 IMP
mmu Itpr1 inositol 1,4,5-trisphosphate receptor 1 16438 IMP
mmu Pml promyelocytic leukemia 18854 IMP
mmu Trp53 transformation related protein 53 22059 IMP
mmu Xbp1 X-box binding protein 1 22433 IMP
mmu Map3k5 mitogen-activated protein kinase kinase kinase 5 26408 IMP
mmu Ern2 endoplasmic reticulum (ER) to nucleus signalling 2 26918 IBA,IDA
mmu Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 26926 IMP
mmu Ero1a endoplasmic reticulum oxidoreductase 1 alpha 50527 IMP
mmu Atp2a3 ATPase, Ca++ transporting, ubiquitous 53313 ISO
mmu Ube2k ubiquitin-conjugating enzyme E2K 53323 ISO
mmu Gsk3b glycogen synthase kinase 3 beta 56637 IDA
mmu Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 58801 IMP
mmu Rnf186 ring finger protein 186 66825 IBA,ISO
mmu Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 66861 ISO
mmu Chac1 ChaC, cation transport regulator 1 69065 ISO
mmu Qrich1 glutamine-rich 1 69232 ISO
mmu Dab2ip disabled 2 interacting protein 69601 IMP
mmu Brsk2 BR serine/threonine kinase 2 75770 ISO
mmu Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 78943 IBA,IDA,IMP
mmu Selenok selenoprotein K 80795 ISO
mmu Tmbim6 transmembrane BAX inhibitor motif containing 6 110213 IDA,IMP
mmu Bbc3 BCL2 binding component 3 170770 IBA,IMP,ISO
mmu Bag6 BCL2-associated athanogene 6 224727 IMP
mmu Trib3 tribbles pseudokinase 3 228775 ISO
mmu Tmem117 transmembrane protein 117 320709 IBA,ISO
rno Bcl2 BCL2, apoptosis regulator 24224 ISO
rno Cebpb CCAAT/enhancer binding protein beta 24253 ISO
rno Ins2 insulin 2 24506 ISO
rno Tmbim6 transmembrane BAX inhibitor motif containing 6 24822 ISO
rno Tp53 tumor protein p53 24842 ISO
rno Bax BCL2 associated X, apoptosis regulator 24887 IEA,ISO,ISO,ISS
rno Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 25262 IEA,ISO,ISS
rno Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 25391 IEA,ISO
rno Ddit3 DNA-damage inducible transcript 3 29467 IBA,IEA,ISO,ISO,ISS
rno Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 29702 ISO
rno Apaf1 apoptotic peptidase activating factor 1 78963 ISO
rno Atf4 activating transcription factor 4 79255 ISO,ISS
rno Aifm1 apoptosis inducing factor, mitochondria associated 1 83533 ISO,ISS
rno Gsk3b glycogen synthase kinase 3 beta 84027 ISO
rno Bag6 BAG cochaperone 6 94342 ISO,ISS
rno Casp4 caspase 4 114555 ISO
rno Bak1 BCL2-antagonist/killer 1 116502 ISO
rno Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 116601 ISO
rno Casp12 caspase 12 156117 IEA,ISO,ISO,NAS
rno Ero1a endoplasmic reticulum oxidoreductase 1 alpha 171562 ISO,ISS
rno Dab2ip DAB2 interacting protein 192126 IEA,ISO
rno Trib3 tribbles pseudokinase 3 246273 ISO,ISS
rno Xbp1 X-box binding protein 1 289754 ISO
rno Selenok selenoprotein K 290549 IEA,ISO
rno Brsk2 BR serine/threonine kinase 2 293631 IEA,ISO
rno Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 295690 ISO
rno Qrich1 glutamine-rich 1 301004 IEA,ISO
rno Pml PML nuclear body scaffold 315713 ISO
rno Bbc3 Bcl-2 binding component 3 317673 IBA,ISO,ISS
rno Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 362196 ISO
rno Map3k5 mitogen-activated protein kinase kinase kinase 5 365057 ISO
rno Ern2 endoplasmic reticulum to nucleus signaling 2 365363 IBA,ISO
rno Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 492821 ISO
rno Ern1 endoplasmic reticulum to nucleus signaling 1 498013 IBA,ISO,ISO
rno Tmem117 transmembrane protein 117 500921 IBA,ISO
rno Rnf186 ring finger protein 186 690433 IBA,ISO
gga CEBPB CCAAT/enhancer binding protein beta 396185 IEA
dre tp63 tumor protein p63 260407 IMP
dre atf4a activating transcription factor 4a 406514 ISS
dre tmem117 transmembrane protein 117 406763 IBA,ISS
dre ern1 endoplasmic reticulum to nucleus signaling 1 553551 IBA
dre ddit3 DNA-damage-inducible transcript 3 561924 IBA,IMP
dre ern2 endoplasmic reticulum to nucleus signaling 2 567021 IBA
dre bag6l BCL2 associated athanogene 6, like 751663 ISS
dre bbc3 BCL2 binding component 3 751763 IMP
dme ninaA neither inactivation nor afterpotential A 33271 IMP
dme Cdk5alpha Cdk5 activator-like protein 34385 IGI
dme Cdk5 Cyclin-dependent kinase 5 36727 IGI
dme Mekk1 Mekk1 42253 IGI
dme Ire1 Inositol-requiring enzyme-1 42358 IBA
cel ire-1 Endoribonuclease;Serine/threonine-protein kinase 174305 IBA
sce IRE1 bifunctional endoribonuclease/protein kinase IRE1 856478 IBA
spo ire1 putative serine/threonine protein kinase Ppk4 2542776 IBA


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