GO:0045879 negative regulation of smoothened signaling pathway

32 hsa genes in this database.
38 mmu genes in this database.
38 rno genes in this database.
2 gga genes in this database.
22 dre genes in this database.
51 dme genes in this database.
1 cfa genes in this database.

[QuickGO]

term: negative regulation of smoothened signaling pathway
goid: GO:0045879

Shaded genes do not have GeneChip data. The output was limited up to 100 for each of species.
Species Symbol Gene
coexpression		 Locus
page 		Full name* Entrez Gene ID Evidence*
hsa RUNX2 RUNX family transcription factor 2 860 IEA
hsa CD3E CD3e molecule 916 IEA
hsa MEGF8 multiple EGF like domains 8 1954 ISS
hsa GPC3 glypican 3 2719 ISS
hsa GLI2 GLI family zinc finger 2 2736 IEA
hsa GLI3 GLI family zinc finger 3 2737 ISS
hsa ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 5167
hsa SERPINE2 serpin family E member 2 5270 IEA
hsa PRKACA protein kinase cAMP-activated catalytic subunit alpha 5566
hsa PRKACB protein kinase cAMP-activated catalytic subunit beta 5567
hsa PTCH1 patched 1 5727 ISS,TAS
hsa RB1 RB transcriptional corepressor 1 5925 IEA
hsa RFX4 regulatory factor X4 5992
hsa TULP3 TUB like protein 3 7289 IDA
hsa VCP valosin containing protein 7415 IMP
hsa PTCH2 patched 2 8643 TAS
hsa BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 8945 TAS
hsa GPR37L1 G protein-coupled receptor 37 like 1 9283 IEA
hsa RACK1 receptor for activated C kinase 1 10399 IDA
hsa MGRN1 mahogunin ring finger 1 23295 ISS
hsa GPR161 G protein-coupled receptor 161 23432
hsa ULK3 unc-51 like kinase 3 25989 IDA
hsa HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 26091 IMP
hsa IFT172 intraflagellar transport 172 26160 IEA
hsa SUFU SUFU negative regulator of hedgehog signaling 51684 IMP,TAS
hsa IFT122 intraflagellar transport 122 55764 ISS
hsa HHIP hedgehog interacting protein 64399 ISS
hsa GLIS2 GLIS family zinc finger 2 84662 ISS
hsa KCTD6 potassium channel tetramerization domain containing 6 200845 IDA
hsa KCTD21 potassium channel tetramerization domain containing 21 283219 IDA
hsa KIF7 kinesin family member 7 374654 ISS
hsa MOSMO modulator of smoothened 730094 IBA,ISS
mmu Runx2 runt related transcription factor 2 12393 IMP
mmu Cd3e CD3 antigen, epsilon polypeptide 12501 IDA
mmu Fgfr3 fibroblast growth factor receptor 3 14184 IMP
mmu Gas1 growth arrest specific 1 14451 IDA
mmu Gli2 GLI-Kruppel family member GLI2 14633 IGI
mmu Gli3 GLI-Kruppel family member GLI3 14634 IMP
mmu Rack1 receptor for activated C kinase 1 14694 ISO
mmu Gpc3 glypican 3 14734 IGI,IMP
mmu Hhip Hedgehog-interacting protein 15245 IDA,IDA,IMP
mmu Kif7 kinesin family member 7 16576 IMP
mmu Mgrn1 mahogunin, ring finger 1 17237 IMP
mmu Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 18605
mmu Prkaca protein kinase, cAMP dependent, catalytic, alpha 18747
mmu Prkacb protein kinase, cAMP dependent, catalytic, beta 18749
mmu Ptch1 patched 1 19206 IGI,NAS
mmu Rb1 RB transcriptional corepressor 1 19645 IMP
mmu Sall3 spalt like transcription factor 3 20689 IGI
mmu Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 20720 IGI
mmu Tulp3 tubby-like protein 3 22158 IMP,ISO
mmu Wnt7b wingless-type MMTV integration site family, member 7B 22422 IMP
mmu Sufu SUFU negative regulator of hedgehog signaling 24069 IDA,IMP,IMP,ISO
mmu Sall1 spalt like transcription factor 1 58198 IGI
mmu Herc4 hect domain and RLD 4 67345 ISO
mmu Ift172 intraflagellar transport 172 67661 IMP
mmu Rfx4 regulatory factor X, 4 (influences HLA class II expression) 71137
mmu Kctd6 potassium channel tetramerisation domain containing 6 71393 ISO
mmu Ulk3 unc-51-like kinase 3 71742 ISO
mmu Traf3ip1 TRAF3 interacting protein 1 74019
mmu Ift122 intraflagellar transport 122 81896 IGI,IMP,IMP
mmu Glis2 GLIS family zinc finger 2 83396 IMP
mmu Cdk20 cyclin-dependent kinase 20 105278
mmu Gpr37l1 G protein-coupled receptor 37-like 1 171469 IMP
mmu Kctd11 potassium channel tetramerisation domain containing 11 216858 IDA
mmu Mosmo modulator of smoothened 233812 IBA,IMP
mmu Gpr161 G protein-coupled receptor 161 240888
mmu Vcp valosin containing protein 269523 ISO
mmu Megf8 multiple EGF-like-domains 8 269878 IMP
mmu Kctd21 potassium channel tetramerisation domain containing 21 622320 ISO
rno Rb1 RB transcriptional corepressor 1 24708 IEA,ISO
rno Gpc3 glypican 3 25236 IEA,ISO,ISS
rno Prkaca protein kinase cAMP-activated catalytic subunit alpha 25636
rno Serpine2 serpin family E member 2 29366 IEA,ISO
rno Rack1 receptor for activated C kinase 1 83427 ISO
rno Fgfr3 fibroblast growth factor receptor 3 84489 ISO
rno Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 85496
rno Ptch1 patched 1 89830 ISO
rno Megf8 multiple EGF-like-domains 8 114029 IEA,ISO,ISS
rno Ift172 intraflagellar transport 172 116475 ISO
rno Vcp valosin-containing protein 116643 ISO
rno Gli3 GLI family zinc finger 3 140588 ISO
rno Gpr37l1 G protein-coupled receptor 37-like 1 252939 IEA,ISO
rno Gpr161 G protein-coupled receptor 161 289180
rno Hhip Hedgehog-interacting protein 291936 ISO,ISO
rno Kif7 kinesin family member 7 293047 ISO
rno Prkacb protein kinase cAMP-activated catalytic subunit beta 293508
rno Mgrn1 mahogunin ring finger 1 302938 IEA,ISO,ISS
rno Glis2 GLIS family zinc finger 2 302946 ISO
rno Gli2 GLI family zinc finger 2 304729 ISO
rno Kctd6 potassium channel tetramerization domain containing 6 305792 ISO
rno Sall1 spalt-like transcription factor 1 307740 ISO
rno Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 309758 ISO
rno Ift122 intraflagellar transport 122 312651 ISO,ISO
rno Wnt7b Wnt family member 7B 315196 ISO
rno Cd3e CD3e molecule 315609 ISO
rno Sufu SUFU negative regulator of hedgehog signaling 361769 ISO,ISO
rno Traf3ip1 TRAF3 interacting protein 1 363286
rno Kctd11 potassium channel tetramerization domain containing 11 363634 ISO
rno Cdk20 cyclin-dependent kinase 20 364666
rno Sall3 spalt-like transcription factor 3 364910 ISO
rno Runx2 RUNX family transcription factor 2 367218 IEA,ISO
rno Kctd21 potassium channel tetramerization domain containing 21 499209 ISO
rno Rfx4 regulatory factor X4 500818
rno Gas1 growth arrest-specific 1 683470 ISO
rno Tulp3 TUB like protein 3 688749 ISO,ISO
rno Ulk3 unc-51 like kinase 3 691171 ISO,ISS
rno Mosmo modulator of smoothened 102547219 ISO
gga RACK1 receptor for activated C kinase 1 417044 IEA
gga ULK3 unc-51 like kinase 3 769780 ISS
dre ptch2 patched 2 30181 IMP
dre ptch1 patched 1 30189 IMP
dre sox11a SRY-box transcription factor 11a 30602 IGI
dre sox11b SRY-box transcription factor 11b 30603 IGI
dre cdon cell adhesion associated, oncogene regulated 280652 IMP
dre lztfl1 leucine zipper transcription factor-like 1 322226 IDA
dre hhip hedgehog interacting protein 326102 IMP
dre sox4a SRY-box transcription factor 4a 336346 IGI
dre gpr161a G protein-coupled receptor 161a 368421
dre gpc3 glypican 3 387365 ISS
dre sox4b SRY-box transcription factor 4b 393875 IGI
dre ube2d2 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) 393934 IMP
dre rfx4 regulatory factor X, 4 403016
dre ift122 intraflagellar transport 122 homolog (Chlamydomonas) 405826 ISS
dre kif7 kinesin family member 7 544651 IMP
dre gatad2b GATA zinc finger domain containing 2B 562045 IMP
dre rest RE1-silencing transcription factor 564772 IMP
dre rerea arginine-glutamic acid dipeptide (RE) repeats a 569081 IMP
dre mosmob modulator of smoothened b 767723 IBA,ISS
dre mgrn1a mahogunin, ring finger 1a 793939 ISS
dre prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit 100001198
dre sufu suppressor of fused homolog (Drosophila) 100001615 IGI,IMP
dme Roc1a Regulator of cullins 1a 31014 IMP
dme sgg shaggy 31248 IDA,IGI,IMP
dme sqh spaghetti squash 31554 IMP
dme PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein 31979 IMP
dme CkIalpha Casein kinase Ialpha 32221 IMP
dme Gbeta13F G protein beta-subunit 13F 32544 IGI
dme fu fused 32855 IGI,IMP
dme Ulp1 Ulp1 32910 IGI
dme Su(dx) Suppressor of deltex 33379 IGI
dme Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 33458 IMP
dme Rack1 Receptor of activated protein kinase C 1 34070 IGI,IMP
dme Pka-C1 Protein kinase, cAMP-dependent, catalytic subunit 1 34284 IDA,IGI,IMP
dme Cul3 Cullin 3 34896 IMP
dme Nedd8 Nedd8 35151 IMP
dme cos costa 35653 IDA,IGI,IMP
dme Cul1 Cullin 1 35742 IDA,IMP
dme Cul4 Cullin 4 35780 IMP
dme ptc patched 35851 IDA,IGI,IMP
dme TER94 TER94 36040 IMP
dme Uba3 Ubiquitin-like activating enzyme 3 36539 IMP
dme Smurf SMAD specific E3 ubiquitin protein ligase 36999 IMP
dme Synj Synaptojanin 37517 IMP
dme Sac1 Sac1 phosphatase 38137 IMP
dme Herc4 HECT and RLD domain containing E3 ubiquitin ligase 4 38151 IMP
dme HDAC1 Histone deacetylase 1 38565 IMP,IPI
dme tow target of wingless 38755 IMP
dme UbcE2M NEDD8-conjugating enzyme UbcE2M 38916 IMP
dme Ufd1-like Ubiquitin fusion-degradation 1-like 39254 IMP
dme Nedd4 Nedd4 39958 IGI
dme Gbeta76C G protein beta-subunit 76C 40148 IGI
dme CG14182 uncharacterized protein 40181 IBA
dme Pka-R1 Protein kinase, cAMP-dependent, regulatory subunit type 1 40305 IGI,IMP
dme Su(fu) Suppressor of fused 41565 IDA,IGI,IMP
dme pic piccolo 41611 IMP
dme rdx roadkill 41704 IGI,IMP
dme eff effete 41785 IMP
dme slmb supernumerary limbs 42504 IDA,IGI,IMP
dme Pp1alpha-96A Protein phosphatase 1alpha at 96A 42922 IGI
dme Npl4 Nuclear protein localization 4 43091 IMP
dme wdb widerborst 43312 IMP
dme dco discs overgrown 43673 IMP
dme flw flapwing 44289 IGI
dme Pp4-19C Protein phosphatase 19C 45031 IGI,IMP
dme mts microtubule star 45959 IMP
dme Gug Grunge 46156 IMP,IPI
dme Pp1-13C Protein phosphatase 1 at 13C 48531 IGI
dme CG5504 uncharacterized protein 48844 IGI,IPI
dme Gprk2 G protein-coupled receptor kinase 2 49045 IGI
dme Sulf1 Sulfated 53437 IMP
dme krz kurtz 53554 IMP
dme Pp2A-29B Protein phosphatase 2A at 29B 2768940 IMP
cfa CD3E CD3e molecule 442981 IEA


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