| functional annotation |
| Function |
CD3d molecule |
|
| GO BP |
|
GO:0045059 [list] [network] positive thymic T cell selection
|
(11 genes)
|
IBA
ISS
|
 |
|
GO:0050852 [list] [network] T cell receptor signaling pathway
|
(176 genes)
|
TAS
|
|
|
GO:0002250 [list] [network] adaptive immune response
|
(634 genes)
|
IEA
|
|
|
GO:0061024 [list] [network] membrane organization
|
(952 genes)
|
TAS
|
|
|
GO:0050776 [list] [network] regulation of immune response
|
(1286 genes)
|
TAS
|
|
|
GO:0007166 [list] [network] cell surface receptor signaling pathway
|
(2473 genes)
|
IBA
IC
|
|
|
| GO CC |
|
GO:0042105 [list] [network] alpha-beta T cell receptor complex
|
(9 genes)
|
IBA
IDA
|
|
|
GO:0030669 [list] [network] clathrin-coated endocytic vesicle membrane
|
(72 genes)
|
TAS
|
|
|
GO:0042101 [list] [network] T cell receptor complex
|
(148 genes)
|
IDA
|
|
|
GO:0009897 [list] [network] external side of plasma membrane
|
(415 genes)
|
IBA
|
|
|
GO:0016021 [list] [network] integral component of membrane
|
(5388 genes)
|
IEA
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(5772 genes)
|
TAS
|
|
|
GO:0005737 [list] [network] cytoplasm
|
(11897 genes)
|
NAS
|
|
|
| GO MF |
|
GO:0004888 [list] [network] transmembrane signaling receptor activity
|
(1369 genes)
|
IBA
IC
|
|
|
GO:0042802 [list] [network] identical protein binding
|
(1971 genes)
|
IDA
|
|
|
GO:0005515 [list] [network] protein binding
|
(13898 genes)
|
IPI
|
|
|
| KEGG |
hsa04640 [list] [network] Hematopoietic cell lineage (99 genes) |
 |
| hsa04658 [list] [network] Th1 and Th2 cell differentiation (92 genes) |
|
| hsa04659 [list] [network] Th17 cell differentiation (108 genes) |
|
| hsa04660 [list] [network] T cell receptor signaling pathway (104 genes) |
|
| hsa05142 [list] [network] Chagas disease (102 genes) |
|
| hsa05162 [list] [network] Measles (139 genes) |
|
| hsa05166 [list] [network] Human T-cell leukemia virus 1 infection (222 genes) |
|
| hsa05169 [list] [network] Epstein-Barr virus infection (202 genes) |
|
| hsa05170 [list] [network] Human immunodeficiency virus 1 infection (212 genes) |
|
| hsa05235 [list] [network] PD-L1 expression and PD-1 checkpoint pathway in cancer (89 genes) |
|
| hsa05340 [list] [network] Primary immunodeficiency (38 genes) |
|
| Protein |
NP_000723.1
NP_001035741.1
|
| BLAST |
NP_000723.1
NP_001035741.1
|
| Orthologous |
[Ortholog page]
Cd3d (mmu)
Cd3d (rno)
CD3D (gga)
CD3D (cfa)
CD3D (mcc)
CD3D (fca)
|
Subcellular
localization
wolf |
|
extr 8,
mito 1
|
(predict for NP_000723.1)
|
|
extr 6,
mito 2,
nucl 1,
cyto_nucl 1,
E.R._mito 1,
mito_pero 1
|
(predict for NP_001035741.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| hsa04660 |
T cell receptor signaling pathway |
9 |
 |
| hsa04640 |
Hematopoietic cell lineage |
6 |
 |
| hsa04658 |
Th1 and Th2 cell differentiation |
6 |
 |
| hsa04659 |
Th17 cell differentiation |
6 |
 |
| hsa05340 |
Primary immunodeficiency |
6 |
 |
Genes directly connected with CD3D on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 23.1 |
CD3G |
CD3g molecule |
[detail] |
48 |
917 |
| 21.3 |
CD3E |
CD3e molecule |
[detail] |
43 |
916 |
| 19.4 |
CD2 |
CD2 molecule |
[detail] |
13 |
914 |
| 11.9 |
LCK |
LCK proto-oncogene, Src family tyrosine kinase |
[detail] |
22 |
3932 |
| 8.9 |
GRAP2 |
GRB2 related adaptor protein 2 |
[detail] |
2 |
9402 |
| 7.6 |
CD52 |
CD52 molecule |
[detail] |
4 |
1043 |
| 7.3 |
IL2RG |
interleukin 2 receptor subunit gamma |
[detail] |
15 |
3561 |
|
Coexpressed
gene list |
[Coexpressed gene list for CD3D]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
CD3D Gene
