| functional annotation |
| Function |
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase |
|
| GO BP |
|
GO:0006189 [list] [network] 'de novo' IMP biosynthetic process
|
(4 genes)
|
IEA
|
 |
|
GO:0006164 [list] [network] purine nucleotide biosynthetic process
|
(129 genes)
|
IEA
|
|
|
GO:0008152 [list] [network] metabolic process
|
(7626 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0004638 [list] [network] phosphoribosylaminoimidazole carboxylase activity
|
(1 genes)
|
IEA
|
|
|
GO:0004639 [list] [network] phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
|
(1 genes)
|
IEA
|
|
|
GO:0043727 [list] [network] 5-amino-4-imidazole carboxylate lyase activity
|
(1 genes)
|
IEA
|
|
|
GO:0016831 [list] [network] carboxy-lyase activity
|
(35 genes)
|
IEA
|
|
|
GO:0016874 [list] [network] ligase activity
|
(164 genes)
|
IEA
|
|
|
GO:0016829 [list] [network] lyase activity
|
(196 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1396 genes)
|
IEA
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(2052 genes)
|
IEA
|
|
|
GO:0042802 [list] [network] identical protein binding
|
(2357 genes)
|
ISO
|
|
|
GO:0003824 [list] [network] catalytic activity
|
(5635 genes)
|
IEA
|
|
|
| KEGG |
mmu00230 [list] [network] Purine metabolism (133 genes) |
 |
| Protein |
NP_001343900.1
NP_001343901.1
NP_001343902.1
NP_001343903.1
NP_080215.1
XP_006535246.1
|
| BLAST |
NP_001343900.1
NP_001343901.1
NP_001343902.1
NP_001343903.1
NP_080215.1
XP_006535246.1
|
| Orthologous |
[Ortholog page]
PAICS (hsa)
Paics (dme)
Paics (rno)
paic-1 (cel)
paics (dre)
PAICS (gga)
PAICS (mcc)
LOC100359876 (rno)
PAICS (cfa)
PAICS (fca)
|
Subcellular
localization
wolf |
|
cyto 8,
mito 1
|
(predict for NP_001343900.1)
|
|
cyto 8,
mito 1
|
(predict for NP_001343901.1)
|
|
cyto 8,
mito 1
|
(predict for NP_001343902.1)
|
|
cyto 8,
mito 1
|
(predict for NP_001343903.1)
|
|
cyto 8,
mito 1
|
(predict for NP_080215.1)
|
|
cyto 8,
mito 1
|
(predict for XP_006535246.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu00230 |
Purine metabolism |
4 |
 |
| mmu05010 |
Alzheimer disease |
2 |
 |
| mmu05022 |
Pathways of neurodegeneration - multiple diseases |
2 |
 |
| mmu01200 |
Carbon metabolism |
2 |
 |
| mmu00250 |
Alanine, aspartate and glutamate metabolism |
2 |
 |
Genes directly connected with Paics on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 8.3 |
Eif2a |
eukaryotic translation initiation factor 2A |
[detail] |
0 |
229317 |
| 8.2 |
Ppat |
phosphoribosyl pyrophosphate amidotransferase |
[detail] |
1 |
231327 |
| 7.7 |
Adh5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
[detail] |
0 |
11532 |
| 6.5 |
Grsf1 |
G-rich RNA sequence binding factor 1 |
[detail] |
0 |
231413 |
| 5.8 |
Adk |
adenosine kinase |
[detail] |
0 |
11534 |
|
Coexpressed
gene list |
[Coexpressed gene list for Paics]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Paics Gene
