| functional annotation |
| Function |
ubiquitin carboxyl-terminal esterase L5 |
|
| GO BP |
|
GO:0021670 [list] [network] lateral ventricle development
|
(13 genes)
|
IMP
|
 |
|
GO:0048853 [list] [network] forebrain morphogenesis
|
(17 genes)
|
IMP
|
|
|
GO:0032435 [list] [network] negative regulation of proteasomal ubiquitin-dependent protein catabolic process
|
(37 genes)
|
ISO
|
|
|
GO:0045880 [list] [network] positive regulation of smoothened signaling pathway
|
(43 genes)
|
ISO
|
|
|
GO:0030901 [list] [network] midbrain development
|
(46 genes)
|
IMP
|
|
|
GO:0016579 [list] [network] protein deubiquitination
|
(106 genes)
|
IBA
ISO
|
|
|
GO:0061136 [list] [network] regulation of proteasomal protein catabolic process
|
(181 genes)
|
ISO
|
|
|
GO:0006310 [list] [network] DNA recombination
|
(210 genes)
|
IEA
|
|
|
GO:0006281 [list] [network] DNA repair
|
(450 genes)
|
IEA
|
|
|
GO:0006511 [list] [network] ubiquitin-dependent protein catabolic process
|
(498 genes)
|
IEA
|
|
|
GO:0006974 [list] [network] cellular response to DNA damage stimulus
|
(691 genes)
|
IEA
|
|
|
GO:0006508 [list] [network] proteolysis
|
(1144 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0070628 [list] [network] proteasome binding
|
(20 genes)
|
ISO
|
|
|
GO:0004843 [list] [network] thiol-dependent deubiquitinase
|
(99 genes)
|
IBA
ISO
|
|
|
GO:0008234 [list] [network] cysteine-type peptidase activity
|
(183 genes)
|
IEA
|
|
|
GO:0004866 [list] [network] endopeptidase inhibitor activity
|
(215 genes)
|
ISO
|
|
|
GO:0008233 [list] [network] peptidase activity
|
(649 genes)
|
IEA
|
|
|
GO:0016787 [list] [network] hydrolase activity
|
(2400 genes)
|
IEA
|
|
|
| KEGG |
|
|
| Protein |
NP_001153338.1
NP_062508.2
XP_006529823.1
|
| BLAST |
NP_001153338.1
NP_062508.2
XP_006529823.1
|
| Orthologous |
[Ortholog page]
Uch-L5R (dme)
Uch-L5 (dme)
UCHL5 (hsa)
ubh-4 (cel)
Uchl5 (rno)
uchl5 (dre)
UCHL5 (gga)
UCHL5 (cfa)
UCHL5 (mcc)
vma7 (spo)
UCHL5 (fca)
|
Subcellular
localization
wolf |
|
cyto 4,
cyto_nucl 3,
nucl 2,
cysk 2,
mito 1
|
(predict for NP_001153338.1)
|
|
cyto 4,
cyto_nucl 3,
nucl 2,
cysk 2,
mito 1
|
(predict for NP_062508.2)
|
|
cysk 8,
cyto 1
|
(predict for XP_006529823.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu05020 |
Prion disease |
8 |
 |
| mmu05010 |
Alzheimer disease |
8 |
 |
| mmu05022 |
Pathways of neurodegeneration - multiple diseases |
8 |
 |
| mmu03050 |
Proteasome |
7 |
 |
| mmu05012 |
Parkinson disease |
7 |
 |
Genes directly connected with Uchl5 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 7.5 |
Ola1 |
Obg-like ATPase 1 |
[detail] |
0 |
67059 |
| 7.4 |
Cacybp |
calcyclin binding protein |
[detail] |
0 |
12301 |
| 7.0 |
Psmd12 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 |
[detail] |
0 |
66997 |
| 6.3 |
Uchl3 |
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
[detail] |
11 |
50933 |
|
Coexpressed
gene list |
[Coexpressed gene list for Uchl5]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Uchl5 Gene
