| functional annotation |
| Function |
alanyl-tRNA synthetase |
|
| GO BP |
|
GO:0140018 [list] [network] regulation of cytoplasmic translational fidelity
|
(1 genes)
|
IMP
|
 |
|
GO:0006419 [list] [network] alanyl-tRNA aminoacylation
|
(3 genes)
|
IBA
IDA
IMP
ISO
|
|
|
GO:0021680 [list] [network] cerebellar Purkinje cell layer development
|
(38 genes)
|
IMP
|
|
|
GO:0043039 [list] [network] tRNA aminoacylation
|
(43 genes)
|
IEA
|
|
|
GO:0050885 [list] [network] neuromuscular process controlling balance
|
(70 genes)
|
IMP
|
|
|
GO:0006400 [list] [network] tRNA modification
|
(76 genes)
|
IBA
IDA
IMP
|
|
|
GO:0050905 [list] [network] neuromuscular process
|
(185 genes)
|
IMP
|
|
|
GO:0043524 [list] [network] negative regulation of neuron apoptotic process
|
(186 genes)
|
IMP
|
|
|
GO:0006412 [list] [network] translation
|
(350 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0002196 [list] [network] Ser-tRNA(Ala) hydrolase activity
|
(2 genes)
|
IDA
IMP
|
|
|
GO:0004813 [list] [network] alanine-tRNA ligase activity
|
(3 genes)
|
IBA
IDA
ISO
|
|
|
GO:0002161 [list] [network] aminoacyl-tRNA editing activity
|
(13 genes)
|
IBA
IDA
ISO
|
|
|
GO:0004812 [list] [network] aminoacyl-tRNA ligase activity
|
(41 genes)
|
IEA
|
|
|
GO:0016597 [list] [network] amino acid binding
|
(64 genes)
|
IBA
ISO
|
|
|
GO:0000049 [list] [network] tRNA binding
|
(70 genes)
|
IBA
ISO
|
|
|
GO:0045182 [list] [network] translation regulator activity
|
(141 genes)
|
IMP
|
|
|
GO:0016874 [list] [network] ligase activity
|
(164 genes)
|
IEA
|
|
|
GO:0003723 [list] [network] RNA binding
|
(1194 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1396 genes)
|
IBA
ISO
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(2052 genes)
|
IEA
|
|
|
GO:0003676 [list] [network] nucleic acid binding
|
(3446 genes)
|
IEA
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(3573 genes)
|
IEA
|
|
|
GO:0005515 [list] [network] protein binding
|
(9507 genes)
|
IPI
|
|
|
| KEGG |
mmu00970 [list] [network] Aminoacyl-tRNA biosynthesis (66 genes) |
 |
| Protein |
NP_666329.2
XP_006530985.1
XP_006530987.1
|
| BLAST |
NP_666329.2
XP_006530985.1
XP_006530987.1
|
| Orthologous |
[Ortholog page]
AARS1 (hsa)
AlaRS (dme)
AARS2 (hsa)
aars-2 (cel)
aars-1 (cel)
Aars2 (mmu)
Aars1 (rno)
Aars2 (rno)
aars1 (dre)
AARS1 (gga)
AARS2 (gga)
AARS2 (cfa)
AARS1 (cfa)
AARS2 (mcc)
AARS1 (mcc)
aars2 (dre)
ALA1 (sce)
AARS1 (fca)
AARS2 (fca)
|
Subcellular
localization
wolf |
|
cyto_nucl 5,
nucl 5,
cyto 5,
cyto_golg 3
|
(predict for NP_666329.2)
|
|
cyto_nucl 5,
nucl 5,
cyto 5,
cyto_golg 3
|
(predict for XP_006530985.1)
|
|
cyto_nucl 5,
nucl 5,
cyto 5,
cyto_golg 3
|
(predict for XP_006530987.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu00970 |
Aminoacyl-tRNA biosynthesis |
12 |
 |
| mmu01230 |
Biosynthesis of amino acids |
2 |
 |
| mmu04150 |
mTOR signaling pathway |
2 |
 |
Genes directly connected with Aars on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 16.8 |
Yars |
tyrosyl-tRNA synthetase |
[detail] |
4 |
107271 |
| 14.7 |
Mars1 |
methionine-tRNA synthetase 1 |
[detail] |
0 |
216443 |
| 14.3 |
Nars |
asparaginyl-tRNA synthetase |
[detail] |
2 |
70223 |
| 8.7 |
Atf5 |
activating transcription factor 5 |
[detail] |
0 |
107503 |
| 8.2 |
Slc3a2 |
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |
[detail] |
2 |
17254 |
| 8.0 |
Wars |
tryptophanyl-tRNA synthetase |
[detail] |
2 |
22375 |
| 7.7 |
Lonp1 |
lon peptidase 1, mitochondrial |
[detail] |
0 |
74142 |
| 5.5 |
Uhrf1bp1 |
UHRF1 (ICBP90) binding protein 1 |
[detail] |
0 |
224648 |
|
Coexpressed
gene list |
[Coexpressed gene list for Aars]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Aars Gene
