| functional annotation |
| Function |
leukotriene A4 hydrolase |
|
| GO BP |
|
GO:0019370 [list] [network] leukotriene biosynthetic process
|
(13 genes)
|
IBA
ISO
|
 |
|
GO:0006691 [list] [network] leukotriene metabolic process
|
(24 genes)
|
ISO
|
|
|
GO:0043171 [list] [network] peptide catabolic process
|
(26 genes)
|
IBA
ISO
|
|
|
GO:0006508 [list] [network] proteolysis
|
(1144 genes)
|
IEA
|
|
|
GO:0044267 [list] [network] cellular protein metabolic process
|
(2955 genes)
|
ISO
|
|
|
| GO CC |
|
| GO MF |
|
GO:0004463 [list] [network] leukotriene-A4 hydrolase activity
|
(1 genes)
|
IBA
ISO
|
|
|
GO:0045148 [list] [network] tripeptide aminopeptidase activity
|
(2 genes)
|
IEA
|
|
|
GO:0004301 [list] [network] epoxide hydrolase activity
|
(5 genes)
|
IBA
ISO
|
|
|
GO:0070006 [list] [network] metalloaminopeptidase activity
|
(23 genes)
|
ISO
|
|
|
GO:0004177 [list] [network] aminopeptidase activity
|
(36 genes)
|
IBA
ISO
|
|
|
GO:0008237 [list] [network] metallopeptidase activity
|
(188 genes)
|
IEA
|
|
|
GO:0008233 [list] [network] peptidase activity
|
(649 genes)
|
IEA
|
|
|
GO:0008270 [list] [network] zinc ion binding
|
(700 genes)
|
ISO
|
|
|
GO:0016787 [list] [network] hydrolase activity
|
(2400 genes)
|
IEA
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(3573 genes)
|
IEA
|
|
|
GO:0005515 [list] [network] protein binding
|
(9507 genes)
|
IPI
|
|
|
| KEGG |
mmu00590 [list] [network] Arachidonic acid metabolism (86 genes) |
 |
| Protein |
NP_001300826.1
NP_032543.2
|
| BLAST |
NP_001300826.1
NP_032543.2
|
| Orthologous |
[Ortholog page]
LTA4H (hsa)
CG10602 (dme)
ltah-1.2 (cel)
ltah-1.1 (cel)
Lta4h (rno)
lta4h (dre)
LTA4H (gga)
LTA4H (cfa)
LTA4H (mcc)
LAP2 (sce)
lsm7 (spo)
LTA4H (fca)
|
Subcellular
localization
wolf |
|
cyto 5,
cyto_nucl 5,
nucl 3
|
(predict for NP_001300826.1)
|
|
cyto 6,
cyto_nucl 5,
nucl 3,
mito 1
|
(predict for NP_032543.2)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu01200 |
Carbon metabolism |
8 |
 |
| mmu00010 |
Glycolysis / Gluconeogenesis |
8 |
 |
| mmu01230 |
Biosynthesis of amino acids |
6 |
 |
| mmu00030 |
Pentose phosphate pathway |
4 |
 |
| mmu04066 |
HIF-1 signaling pathway |
4 |
 |
Genes directly connected with Lta4h on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 4.7 |
Gpi1 |
glucose-6-phosphate isomerase 1 |
[detail] |
0 |
14751 |
| 4.4 |
Vps26b |
VPS26 retromer complex component B |
[detail] |
0 |
69091 |
| 4.3 |
Hmgn2 |
high mobility group nucleosomal binding domain 2 |
[detail] |
0 |
15331 |
| 3.8 |
Me2 |
malic enzyme 2, NAD(+)-dependent, mitochondrial |
[detail] |
0 |
107029 |
|
Coexpressed
gene list |
[Coexpressed gene list for Lta4h]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Lta4h Gene
