| functional annotation |
| Function |
carbonyl reductase 1 |
|
| GO BP |
|
GO:1905344 [list] [network] prostaglandin catabolic process
|
(4 genes)
|
ISO
|
 |
|
GO:0042376 [list] [network] phylloquinone catabolic process
|
(6 genes)
|
ISO
|
|
|
GO:0042373 [list] [network] vitamin K metabolic process
|
(8 genes)
|
ISO
|
|
|
GO:0032570 [list] [network] response to progesterone
|
(19 genes)
|
ISO
|
|
|
GO:0006706 [list] [network] steroid catabolic process
|
(27 genes)
|
ISO
|
|
|
GO:0032355 [list] [network] response to estradiol
|
(56 genes)
|
ISO
|
|
|
GO:0017144 [list] [network] drug metabolic process
|
(66 genes)
|
ISO
|
|
|
GO:2000379 [list] [network] positive regulation of reactive oxygen species metabolic process
|
(77 genes)
|
ISO
|
|
|
| GO CC |
|
GO:0035003 [list] [network] subapical complex
|
(6 genes)
|
IDA
|
|
|
GO:0005902 [list] [network] microvillus
|
(103 genes)
|
ISO
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(5442 genes)
|
ISO
|
|
|
GO:0005634 [list] [network] nucleus
|
(7226 genes)
|
ISO
|
|
|
GO:0005737 [list] [network] cytoplasm
|
(11434 genes)
|
IEA
|
|
|
GO:0043231 [list] [network] intracellular membrane-bounded organelle
|
(11551 genes)
|
ISO
|
|
|
| GO MF |
|
GO:0047021 [list] [network] 15-hydroxyprostaglandin dehydrogenase (NADP+) activity
|
(1 genes)
|
IEA
|
|
|
GO:0050221 [list] [network] prostaglandin-E2 9-reductase activity
|
(1 genes)
|
IEA
|
|
|
GO:0004090 [list] [network] carbonyl reductase (NADPH) activity
|
(7 genes)
|
IBA
ISO
TAS
|
|
|
GO:0047020 [list] [network] 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
|
(10 genes)
|
IEA
|
|
|
GO:0016655 [list] [network] oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
|
(42 genes)
|
ISO
|
|
|
GO:0016491 [list] [network] oxidoreductase activity
|
(801 genes)
|
IEA
|
|
|
| KEGG |
mmu00590 [list] [network] Arachidonic acid metabolism (86 genes) |
 |
| mmu00790 [list] [network] Folate biosynthesis (26 genes) |
|
| mmu00980 [list] [network] Metabolism of xenobiotics by cytochrome P450 (73 genes) |
|
| mmu05204 [list] [network] Chemical carcinogenesis - DNA adducts (84 genes) |
|
| mmu05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (222 genes) |
|
| Protein |
NP_031646.2
|
| BLAST |
NP_031646.2
|
| Orthologous |
[Ortholog page]
CBR1 (hsa)
CBR3 (hsa)
Cbr1 (rno)
Cbr3 (mmu)
Cbr3 (rno)
cbr1l (dre)
cbr1 (dre)
CBR3 (gga)
CBR3 (cfa)
LOC610164 (cfa)
CBR3 (mcc)
CBR1 (mcc)
LOC792137 (dre)
LOC100360601 (rno)
LOC100688446 (cfa)
CBR3 (fca)
LOC101083875 (fca)
LOC101084134 (fca)
LOC101084388 (fca)
LOC102556347 (rno)
LOC102901316 (fca)
LOC119867057 (cfa)
LOC119867058 (cfa)
LOC120093083 (rno)
|
Subcellular
localization
wolf |
|
mito 6,
cyto 4
|
(predict for NP_031646.2)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu05208 |
Chemical carcinogenesis - reactive oxygen species |
12 |
 |
| mmu00980 |
Metabolism of xenobiotics by cytochrome P450 |
8 |
 |
| mmu05200 |
Pathways in cancer |
8 |
 |
| mmu05204 |
Chemical carcinogenesis - DNA adducts |
7 |
 |
| mmu05225 |
Hepatocellular carcinoma |
7 |
 |
Genes directly connected with Cbr1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 7.0 |
Acot13 |
acyl-CoA thioesterase 13 |
[detail] |
0 |
66834 |
| 6.9 |
Setd4 |
SET domain containing 4 |
[detail] |
2 |
224440 |
| 6.6 |
Gsta4 |
glutathione S-transferase, alpha 4 |
[detail] |
0 |
14860 |
| 6.2 |
Cbr3 |
carbonyl reductase 3 |
[detail] |
3 |
109857 |
|
Coexpressed
gene list |
[Coexpressed gene list for Cbr1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Cbr1 Gene
