Publication for Sqstm1 and Gabarapl1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Sqstm1	sequestosome 1	18412			[link]
mmu	Gabarapl1	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1	57436

Pubmed ID	Priority	Text
27427974	0.98	SQSTM1, CALCOCO2, ULK1, ATG2B, ATG4D, ATG5, and GABARAPL1 upon SFN treatment (Fig. 1C).
	0.98	Sqstm1, Calcoco2, Ulk1, Atg2b, Atg4d, Atg5, Atg7 and Gabarapl1 was observed in Nfe2l2-KO MEFs.
	0.98	Sqstm1, Calcoco2, Ulk1, Atg2b, Atg5, Atg7 and Gabarapl1.
	0.98	SQSTM1 and CALCOCO2), autophagosome formation (ATG4D, ATG7 and GABARAPL1), elongation (ATG2B and ATG5), and autolysosome clearance (ATG4D).
	0.98	SQSTM1, CALCOCO2, ULK1, AGT5, GABARAPL1 and LC3B) in the AT-nfe2l2-KO mice (Fig. 3).
	0.97	SQSTM1/p62, CALCOCO2/NDP52, ULK1, ATG5 and GABARAPL1.
	0.96	SQSTM1, CALCOCO2, ULK1, ATG5 and GABARAPL1 were reduced in neurons of the AT-nfe2l2-KO mice expressing HsAPP, compared to those of AT-Nfe2l2-WT mice.
	0.91	Sqstm1, Atg2b, and Gabarapl1.
	0.66	Sqstm1, Calcoco2, Ulk1, Atg5, Atg7 and Gabarapl1 exhibited a robust response (Fig. 2E).
23690988	0.98	GABARAPL1 and p62-positively stained vesicles suggesting that the GABARAPL1 staining observed in neurons is due to its association with autophagic vesicles.
	0.98	GABARAPL1 and/or p62, a described substrate of autophagy.
	0.96	GABARAPL1 is predominant in the mouse brain and it interacts with several adaptor proteins for selective autophagy, which degrades unwanted protein aggregates and damaged organelles, such as p62, NBR1 (neighbor of BRCA1) and NIX (NIP3-like protein X ), its extinction might present a more severe phenotype, especially in this organ.
	0.83	GABARAPL1 and p62 in the cell body as well as in the cell processes.
	0.56	p62 only positive vesicles are likely to be autophagosomes containing none or little GABARAPL1.
28104575	0.98	p62 and NDP52), autophagosome formation (ATG4D, ATG7 and GABARAPL1), elongation (ATG2B and ATG5), and autolysosome clearance (ATG4D).
	0.98	p62, Ndp52, Ulk1, Atg2b, Atg4c, Atg5, Atg7 and Gabarapl1.
29477142	0.98	p62 binds to polyubiquitinated proteins and to LC3b or Gabarapl1, thus guiding the cargo into autophagosomes to be digested.
	0.98	Gabarapl1, and p62, with respect to contralateral muscles (Fig. 3a).
30344980	0.98	p62, a chaperone protein that directs polyubiquitinated proteins to the autophagosomes, by directly binding to LC3b and Gabarapl1 proteins and allowing the degradation of protein aggregates via autophagy.
	0.97	p62, was up-regulated as soon as eight hours upon denervation and increased over time, reaching statistical significance within eight to twenty-four hours; while the expression of others, such as Atg7 and Gabarapl1 significantly increased only from day three following denervation.
30840891	0.98	p62, GABARAPL1, and ATG12; they were markedly decreased in IPMK KO MEFs (Figure S2B).
	0.98	p62, GABARAPL1, and ATG12 was rescued by both the WT and kinase-dead forms of IPMK (Figure 2D).
27854220	0.98	Gabarapl1, Bnip3 and Sqstm1, are induced upon fasting and denervation, and that their regulation is driven by the FoxO3 (Forkhead box class O) transcription factor.
30927519	0.98	Gabarapl1, p62, Ulk1, Sirt1 and AMPKalpha1 mRNAs was decreased in FSP27 KO mice compared with WT mice (Figure 1c).
31088970	0.98	GABARAPL1, Atg16L, Atg9A, and TFEB were significantly down-regulated in HD IKKbeta knockout liver, and HTT, mAtg13, Atg14, LC3A, GABARAPL1, p62, and LAMP-2A were significantly down-regulated in NT IKKbeta knockout liver.
30635357	0.97	p62+ inclusions in both SOD1G93A transgenic groups largely colocalized with GABARAPL1 as well as polyubiquitin at P50.
	0.93	p62+ (F) and GABARAPL1+ (G) round-body inclusions in the LSC of SOD1G93A mice.
	0.54	p62 aggregates, however, were not located inside but were outside of the MN somata at P120 and overlapped with GABARAPL1 and polyubiquitin (Fig. S2, I and J).
22998728	0.97	GABARAPL1, and p62 in forebrain specific Atg7 conditional knockout (CamK-Atg7 cKO) mice (Figure 1a,b).
23979425	0.97	Gabarapl1 an 2, Irgm1, lamp1, MAPK14, Map1lc3a (Lc3), Mtor, Pik3c3, Pik3cg, Pten, Snca, Sqstm1 and Wipi1 (Table 1).
29036763	0.97	p62, and a decrease in vacuolar protein sorting 34 (PS34), autophagy-related gene 12 (ATG12), and GABA receptor-associated protein-like 1 gene (GABARAPL1), which are involved in autophagy.
29323772	0.97	p62/SQSTM1, CALCOCO2/NDP52, ULK1, ATG5, and GABARAPL1 are low in Nrf2-deficient mice co-expressing mutant APP (HsAPPV717I) and MAPT (HsMAPTP301L), and these animals have more intracellular aggregates of the mutant proteins.
31096690	0.97	SQSTM1, and GABARAPL1, encoding respectively for the proteins ATF4, USP15, p62 and GABARAPL1, member of the LC3/GABARAP family.
31964384	0.96	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 (GABARAPL1) (24 h, 48 h), and the PINK1/PARK2-related autophagy receptor sequestosome-1 (SQSTM1) (24 h-72 h) were significantly higher in mice subjected to IT-LPS compared with mice subjected to IT-NaCl (Fig. 4a-d).
	0.90	GABARAPL1 (48 h), and SQSTM1 (48 h, 72 h) were higher during the first days post instillation in the IT-LPS mice compared with the control group (Fig. 4e-i).
26034986	0.95	GL1 and SQSTM1 in overexpressing cells compared to non-expressing cells (Fig 3B top panel).
	0.79	SQSTM1 and GABARAPL1 (GL1, another ATG8 family member) or interactions of a second cargo adapter NIX with LC3B or GL1 in MDA-MB-436 cells (Fig 1).
27493873	0.93	Gabarapl1, PI3KIII, Ulk2, Atg12I, Atg4b, and Beclin-1 after 3 or 7 days of denervation.41 Ogata et al. 32 have reported increases in LC3-II and p62/SQSTM1 in soleus and plantaris muscles of rats following 1-3 days of fasting.
27242268	0.92	p62 by antioxidant transcription factor Nrf2, and regulation of ATG14, ULK1, BNIP3, GABARAPL1, and LC3 by clock and BMAL1 have been demonstrated.
30271348	0.87	Sqstm1, Pik3c3 (phosphatidylinositol 3-kinase catalytic subunit type 3), Trp53inp1 (transformation related protein 53 inducible nuclear protein 1), Gabarapl1 (gamma-aminobutyric acid A receptor-associated protein-like 1), Map1lc3b (microtubule-associated protein 1 light chain 3 beta)] was not altered (Figure 5).
26775710	0.74	GABARAPL1 (P=0.0360), PTEN (P=0.0295), SQSTM1 (P=0.0008), and PRKAA1 (P=0.0065) were significantly reduced.