Publication for Yars and Gars

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Yars tyrosyl-tRNA synthetase 107271 [link]
mmu Gars glycyl-tRNA synthetase 353172

Pubmed ID Priority Text
23624402 0.98 Yars, Sars, Wars, Vars, Nars, Mars, Gars, Iars and Eprs) and four initiation factors (Eif2s2, Eif3c, Eif4g2 and Eif5), and, as expected, the UPR (Fig. 1e and Supplementary Fig. S1h).
26138142 0.98 GARS and YARS proteins were reported to be mislocalized in mouse neuroblastoma (N2A), human neuroblastoma (SH-SY5Y) and mouse motor neuron (MN-1) cell lines.
28469666 0.92 GARS proteins, whereas Jordanova et al. (2006) identified different subcellular distributions of YARS in neuronal and non-neuronal cells, which they referred to as the tear-drop effect.
17653046 0.78 Yars, Gars, Tars), amino acid transport (Slc3a2, Slc6a6, Slc7a1, Slc38a2), regulation of transcription (including Egr1, Egr4, Nr4a1, Nr4a3, c-fos), and cell death (including Anxa1, Trib3).
20152552 0.77 YARS overexpression suggest that perhaps expression levels of mutant GARS were simply not high enough to generate a phenotype in the experiments reported by Chihara et al[HK1].
0.55 YARS and GARS mutations cause CMT by the same mechanism?
22144914 0.61 GARS, YARS, and AARS all cause CMT.



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