Publication for HOXB2 and HOXB4

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa HOXB2 homeobox B2 3212 [link]
hsa HOXB4 homeobox B4 3214

Pubmed ID Priority Text
21731684 0.98 HOXB4, HOXB5, and HOXB2 genes transformed them into hematopoietic cells.
0.97 HOXB4 or HOXB5, but not HOXB2, induced CD45 expression.
0.96 HoxB2, transfection with HoxB4 and HoxB5 induced CD45 expression in 15.5% and 17.9% of cells, respectively.
0.94 HOXB2, HOXB4, and HOXB5 formed hematopoietic colonies when grown in the CFU-GEMM colony culture assay.
0.91 HOXB4 or HOXB5, transfection of MSCs with the HOXB2 gene did not significantly increase but rather enhanced CD45 expression induced by HOXB4 and HOXB5.
0.90 HOXB4 and HOXB5, but not HOXB2, genes following treatment of HS-5 cells with Aza plus GF.
0.84 HOXB2 induced CD45 expression in only 3.7% of the cells, whereas HOXB4 and HOXB5 constitutively induced CD45 expression in 15.5% and 17.9% of the cells, respectively.
0.70 HoxB2, HoxB4 and HoxB5 genes alters skin fibroblast gene expression.
0.66 HOXB2 with HOXB4, or HOXB2 with HOXB4 and HOXB5, both increased the percentage of cells expressing CD45.
0.65 HOXB2, HOXB4, and HOXB5 altered HS-5 cells.
27010239 0.98 Hoxb2, Hoxb4, Cebpa, Cebpe and PU.1 in GFP+LSK cells.
0.97 Hoxb2, Hoxb4, Cebpa, Cebpe and PU.1 in GFP+LSK cells measured by qPCR.
0.93 Hoxb2 and Hoxb4 promoter-associated CpG islands in WT-transduced cells and hypo-methylation of Hoxb2 in R882H-transduced cells relative to EV-transduced control cells, which was compatible to anterior Hoxb cluster genes expression profile of R882 mutant-transduced stem/progenitor cells (Fig. 2b).
0.63 Hoxb2 and Hoxb4 were upregulated, and Cebpa, Cebpe and PU.1 were downregulated in R882 mutant-transduced LSK cells (Fig. 2a).
23630576 0.97 HOXB2, HOXB4 and HOXB7), three genes contain homeodomain (DLX1, LHX4, and VAX2) and two of them belong to HIST gene family (HIST1H3I and HIST1H4L).
0.97 HOXB2, HOXB4 and HOXB7 together showed the key function in lung cancers.
0.84 HOXB2, HOXB4 and HOXB7) overlapped with the 40 HOXB2 correlated genes.
28697800 0.97 HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8: , p-value = 7.94e-62).
29443048 0.97 HoxB2, HoxA4, HoxB4, HoxB6) markers is not detectable (Figure 3K).
23650565 0.96 HOXB2, HOXB4, HOXB5, HOXB9, and HOXA5).
24947980 0.96 HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, and HOXB13:all located in the 17q21 region) was also determined in both the PBT and SLN metastasis analyzed.
28186679 0.96 HOXB2, and HOXB4 and suppressed HOXB1.
29137433 0.96 HOXB2, HOXB4, HOXC10, and HOXD13 has been found in cervical cancer cell lines.
31489945 0.96 HOXB2, and HOXB4, the expression of OTX2 and EN1 as fore-/mid-brain markers was observed only in iNSCs (Figure 3A).
16895450 0.95 HOXB2, HOXB4, HOXB5, HOXB6, HOXB7, and HOXB9) was limited to the trunk and nondermal samples, whereas HOXD4 and HOXD8 were expressed exclusively in the trunk and proximal leg samples.
24608967 0.94 HOXB2 (-3.4 fold), HOXB4 (-4.2 fold), HOXB5 (-4.1 fold) and HOXB7 (-4.2 fold), and upregulation of HOXC6 (6.8 fold) and HOXC8 (38.2 fold).
26655496 0.94 HOXB2, HOXB3 and HOXB4) (Fig. 1c).
22976993 0.92 Hoxb2 and Hoxb4, Alx-4, AP2 alpha, and Msx1 and Msx2.
25539595 0.92 HOXB (HOXB2 and HOXB4) genes gradually decreased during myeloid maturation (Figure 1A and Additional file 2: Figure S1).
30150715 0.92 HOXB2, HOXB4, HOXB6, HOXB8 and HOXC9 in day 10 aggregates under conditions (i-iv).
31681594 0.92 HOXB2 (P = 0.0026), HOXB3 (P < 0.0001), HOXB4 (P < 0.0001), HOXB6 (P < 0.0001), MEIS1 (P = 0.0001), and PRDM16 (P = 0.0002) genes were all expressed at higher levels compared with high miR-340 expression group.
18317880 0.91 HOXB2 or HOXB4 in T-lymphocytes was previously shown to block the proliferation of activated cells (Care et al. 1995).
27052693 0.91 HOXB2, HOXB4 and HOXA10, which provides a new research direction for ATRA in the treatment of leukemia.
23583175 0.90 HoxB2 and HoxB4 could however be established from precursors treated with RA during the early stages of differentiation (Figure S6).
25875616 0.90 Hoxb2 and Hoxb4 in the R1-R4 rhombomeres of zebrafish, which has major consequences on the cranial nerves formation and neural crest cells (branchial arch 1) migration and differentiation.
28213969 0.89 HOXB2, HOXB4, HOXB6, and HOXC1 (Fig. 3E).
0.56 HOXB2, HOXB4, HOXB6, and HOXC1 profile indicative for spinal cord cells with a rostral cervical identity 15, 25.
18668134 0.88 HOXB2, HOXB3, HOXB4 and MEIS1.
31266935 0.78 HOXB2/B3/B4, although this difference was statistically significant only for HOXB4.
0.71 HOXB4 alone was also significant (Fig. 6c), while HOXB2 and HOXB3 were not significant (Fig. 6d, e).
19282867 0.76 HoxB2, HoxB4, HoxB6) during ESC neuralization with our protocol.
31426381 0.68 HOXB2, HOXB3, HOXB4, LOC404266, HOXB6, NKX2-3, PBX3, C10orf140, LOC100271722, LOC100289444, MEIS1, CPNE8, LOC400931, SDSL, EMR1, and HOXB7.
26397705 0.62 HOXB2, HOXB3, HOXB4 and MEIS1.
30154863 0.60 HOXB2, HOXB4, HOXB9, and HOXC9 (but not HOXA9) in primary AML cases is significantly correlated with survival.
26517675 0.56 HOXB2 (P = 5.95 x 10-8), HOXB3 (P = 5.61 x 10-5), HOXB4 (P = 1.37 x 10-6), HOXB5 (P = 3.90 x 10-6), HOXB6 (P = 2.65 x 10-3), HOXB7 (P = 2.21 x 10-3), HOXB8 (P = 1.78 x 10-2), MEIS1 (P = 6.18 x 10-7), and PBX3 (P = 5.02 x 10-4).



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