Publication for HOXB2 and HOXB3

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa HOXB2 homeobox B2 3212 [link]
hsa HOXB3 homeobox B3 3213

Pubmed ID Priority Text
26517675 0.98 HOXB2 (P = 5.95 x 10-8), HOXB3 (P = 5.61 x 10-5), HOXB4 (P = 1.37 x 10-6), HOXB5 (P = 3.90 x 10-6), HOXB6 (P = 2.65 x 10-3), HOXB7 (P = 2.21 x 10-3), HOXB8 (P = 1.78 x 10-2), MEIS1 (P = 6.18 x 10-7), and PBX3 (P = 5.02 x 10-4).
29300242 0.98 HOXB2, HOXB3, MAP3K, NR5A1, SOX9, and WT1 (genes are from OMIM).
32103106 0.97 HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, CRNDE, CLU, CTSG, COL4A5 and KRT18, among others (Fig. S4).
0.96 HOXB (HOXB2, HOXB3, HOXB6) cluster genes and HOX partners (MEIS1, PBX1, PBX3 and FOXC1) or downstream effectors (MYB, GATA2, FLT3 and CEBPA).
0.92 HOXB gene clusters, among which HOXA9, HOXA5 (with the exception of Kohlmann dataset), HOXA10, HOXB2 and HOXB3 (Fig. 4A,B).
27777423 0.97 Hoxb2, Hoxb3, Hand2 and Ednrb.
0.90 Hoxb2 and Hoxb3); however, they strongly expressed neuronal markers, including peripherin, calretinin, TH and ChAT, that constitute a gene expression profile that is more characteristic of hiPSC-ENs than hiPSC-ENCPs (Supplementary Figure 9D).
27535106 0.97 Hoxb2 and Hoxb4 to be significantly down regulated after homozygous deletion of Dot1l (Fig.4A), while there was also a trend for Hoxb3 that did not reach statistical significance.
28697800 0.97 HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8: , p-value = 7.94e-62).
30237855 0.97 HOXB2, HOXB3, HOXB6, HOXB7, HOXB8, HOXB13, HOXD4, HOXD9 and HOXD11 were downregulated upon JIB-04 treatment in A673 cells (Figure 3B and 3C), and the majority of these were also downregulated in TC32, SK-ES-1 and SK-N-MC cells
30911172 0.97 HOXB2, HOXB3, HAND2 and EDNRB.
31681594 0.97 HOXB2 (P = 0.0026), HOXB3 (P < 0.0001), HOXB4 (P < 0.0001), HOXB6 (P < 0.0001), MEIS1 (P = 0.0001), and PRDM16 (P = 0.0002) genes were all expressed at higher levels compared with high miR-340 expression group.
32015320 0.97 HOXB2, HOXB3, HOXB5, and HOXB8 were upregulated in EOL-1 cells expressing DNMT3A-MT when compared with EV or DNMT3A-WT (Fig. 4a).
32206125 0.97 HOXB2, HOXB3, HOXB4, HOXB6, HOXC6, HOXC9, HOXC11, HOXC13, HOXD1, HOXD3, HOXD4, HOXD8, HOXD10 and HOXD13 were similar in HCC tissues and adjacent nontumor tissues.
17999768 0.96 HOXB2, HOXB3, Neuregulin 1, LMO2 and GATA2 .
0.96 HOXB2, and HOXB3.
18668134 0.96 HOXB2, HOXB3, HOXB4 and MEIS1.
26397705 0.96 HOXB2, HOXB3, HOXB4 and MEIS1) had much higher expression levels in the Inv(16) subtype than that in the t(8;21) subtype.
26655496 0.96 HOXB2, HOXB3 and HOXB4) (Fig. 1c).
28185568 0.95 HOXB2 and HOXB3) that are well reported as genes that are up-regulated in AML.
29214313 0.92 HOXB2 and HOXB3 are transcriptional factors containing homeobox DNA-binding domains.
0.80 HOXB2, HOXB3, HOXB3-AS1) and two genes in the WNT signaling pathways (WNT16, WISP1), three ZIC genes (ZIC4, ZIC2, ZIC5), and one HOX gene (MSX2) were downregulated.
19716816 0.92 Hoxb2, Hoxa3, Hoxb3, and Hoxd3 have between 154 and 192 amino acids C-terminal to the homeodomain while the remaining 34 Hox proteins only have between 6 and 49 amino acids C-terminal to the homeodomain.
23696417 0.92 Hoxb2, Hoxb5, Hoxb7, and Hoxc4 expression is associated with the expansion and self-renewal of MSCs, whereas other Hox family members, including HOXA7, HOXB3, HOXA3, and HOXB13, have been implicated in regulating endothelial differentiation of hMSCs (Phinney et al.,).
31426381 0.91 HOXB2, HOXB3, HOXB4, HOXB6, NKX2-3, PBX3, and MEIS1, amongst others.
0.69 HOXB2, HOXB3, HOXB4, LOC404266, HOXB6, NKX2-3, PBX3, C10orf140, LOC100271722, LOC100289444, MEIS1, CPNE8, LOC400931, SDSL, EMR1, and HOXB7.
24947980 0.90 HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, and HOXB13:all located in the 17q21 region) was also determined in both the PBT and SLN metastasis analyzed.
0.86 HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, and HOXB13) were assessed in 16 cases (7 paired PBT and SLN metastases and 2 unpaired SLN metastases).
25924238 0.90 HOXB2, HOXB3, HOXB8, HOXA3, HOXA4, and HOXA5) that encode transcription factor proteins, and c-kit that encodes a tyrosine kinase.
27586445 0.90 HOXB2 and HOXB3) and the SOX family (SOX9, SOX11 and SOX9) in the fetal cerebellum and cerebrum.
30054336 0.79 HOXB2 and HOXB3 expression were associated with reduced EOC risk; potential molecular mechanisms underlying HOXB suppressive effect on EOC warrant further investigation.
0.63 HOXB2 and HOXB3 were reported across several types of cancers (breast, pancreatic, lung, cervical cancer and acute myeloid leukemia).
29221119 0.79 HOXB2, HOXB3, HOXB5, HOXB6 and HOXD4 are upregulated only in cells with NPM1 mutation.
31266935 0.74 HOXB2 and HOXB3 were not significant (Fig. 6d, e).
26399969 0.73 HOXB3, SMC4, SEPP1, LTBP1, CLIC2, HOXB4, TWISTNB, HIST1H2BC, SIAE, PIEZO2, HLF, ELL2, LOC100507520, HOXB2, FOXC1, HOXB6, HOXB5, EMR1, SNCAIP, RPL39L, USP44, BEX1, TTC27, PTPRC, HENMT1, AK027199, COL4A5, NAP1L5, TIAM1, NPDC1, CLEC11A, SCD5, CCL1, FTO, AK093529, ENSG00000184551, CDKN1B, FAM105A, PHLDA1, HOXA-AS5, LOC100506591, GMDS, TOM1L1, IL12A, DMXL2, SDPR, FOXF1.
24736721 0.67 HOXB2, and HOXB3 (Table S2).
29137433 0.64 HOXB2, HOXB3, HOXB5-9, HOXC4, HOXC5, HOXC13, HOXD1, HOXD9, HOXD10, HOXD11, and HOXD13 (P < 0.001).
27421647 0.63 HOXB2, HOXB3, HOXC3, HOXB5, GADD45G, INHBB, and TP63.



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