Publication for Pbk and Ccnb1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Pbk	PDZ binding kinase	52033			[link]
mmu	Ccnb1	cyclin B1	268697

Pubmed ID	Priority	Text
29594255	0.98	Pbk expression using a small interfering RNA for Pbk reduced bromodeoxyuridine incorporation in mouse insulinoma 6 cells, which was accompanied by a decreased expression of Ccnb1, a regulatory gene involved in mitosis.
	0.98	Pbk expression reduces BrdU incorporation in MIN6 cells, which was accompanied by a decreased expression of Ccnb1.
	0.98	Ccnb1 levels were increased in the islets of pregnant mice, and treatment with HI-TOPK-032 attenuated Ccnb1 expression.
	0.98	Pbk knockdown reduced the mRNA expression levels of several cell-cycle genes, including Ccnb1.
	0.97	Pbk using an adenovirus system in isolated mouse islets increased Ccnb1 expression, and the Pbk inhibitor HI-TOPK-032 suppressed Ccnb1 expression in islets isolated from pregnant mice.
	0.97	Pbk knockdown attenuated the expression of Ccna2, Ccnb1, Ccnb2, Ccnd2, Ccnd3, Cdk1, and Cdk4.
	0.97	Ccnb1 was the only gene to be upregulated in response to the forced expression of Pbk (Fig. 5C).
	0.96	Ccnb1 mRNA, immunoblotting analysis showed that cyclin B1 was reduced in MIN6 cells by Pbk knockdown as well as treatment with HI-TOPK-032 (Fig. 5D and 5E).
	0.96	Pbk knockdown attenuates Ccnb1 expression in MIN6 cells.
	0.96	Ccnb1 by Pbk during pregnancy may play a role in the expansion of beta-cells mass.
	0.96	Pbk and Ccnb1 are involved in the expansion of beta-cell mass in pregnancy is lacking, here we showed evidence to support such a role.
	0.95	Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice
	0.95	Pbk contributes to the expansion of islets during pregnancy and that Ccnb1 may assist Pbk in its role in beta-cell proliferation.
	0.95	Pbk enhanced the expression of Ccnb1 in islets, and the augmented expression of Ccnb1 in islets from pregnant mice was suppressed by the inhibition of Pbk.
	0.95	Pbk increases Ccnb1 and possibly Ccna2.
	0.92	Pbk Regulates Ccnb1 Expression in Islets of Pregnant Mice
	0.69	Ccnb1 expression by a Pbk inhibitor in isolated islets of pregnant mice.
31443434	0.98	Ccnb1, Aurka, Rrm1, Tpx2, Prc1, and Pbk were upregulated in NV HSC while downregulated in NA10hd HSC (Figure 5D).
31475039	0.88	CCNB1, KIF4A, CEP55, and PBK) had a significant impact on survival and belonged to the CIN signature as reported in the literature.
20661276	0.71	Ccnb1, Ccna2, Cenpo, Mcm7, Pbk, Prim1 and Suv39h1).
	0.54	Ccnb1, Cenpo, Mcm7, Pbk, Prim1 and Suv39h1).
26147567	0.51	Pbk, Ccnb1 in addition to many other kinases),