Publication for Aurka and Ccnb1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Aurka	aurora kinase A	20878			[link]
mmu	Ccnb1	cyclin B1	268697

Pubmed ID	Priority	Text
20862286	0.98	Ccnb1, Ccnb2, Plk4, Aurka, and Mad2L1.
	0.98	Ccnb1, Ccnb2, Plks, Aurka, and Mad2L1 .
20307684	0.98	Aurora A. Cyclin B1 is repressed by p53 but must be expressed for mitotic progression; whereas, genes that inhibit mitotic entry and are activated by p53, e.g. p21, Gadd45, and 14-3-3sigma, must be repressed for successful G2-M transition.
22832491	0.98	Aurora-A can phosphorylate the cell cycle regulator CDC25B and thereby affect the centrosomal redistribution of CDK1-Cyclin B1 complexes to promote mitotic entry.
24776885	0.98	cyclin B1 inhibiting separase activation and cyclin B2 accelerating aurora-A-mediated Plk1 activation and centrosome separation.
25628462	0.98	cyclin B1 and AURKA (Aurora kinase A), but was preceded by a an increase in PLK1 (polo-like kinase 1) abundance (Fig. 4A), events which mark the transition of cells from G2 into M phase.
26387737	0.98	Aurora A, Aurora B, Cyclin B1, Cdc20, and UbcH10.
26427040	0.98	Aurka or Stk6, Ccnb1, Trp53 and Cebpalpha as well as the putative gene targets Prc1, Elf5, Klf7, Lats2 and Anp32a (Supplementary Table S1).
26615533	0.98	cyclin B1, was found to be the unique activating binding partner of Cdk1 in the Cdk1-Aurora A-Plk1-Mst2-Nek2A signaling cascade that induces centrosome disjunction.
29074977	0.98	Aurora A kinase activity, prevents the translation of Mos or Ccnb1 reporters, suggesting that MPF is required for their translation in mouse oocytes.
29563798	0.98	Aurora-A kinase localizes to the centrosomes and spindle poles and recruits the cyclin B1-CDK1 complex to drive cell mitosis.
31443434	0.98	Ccnb1, Aurka, Rrm1, Tpx2, Prc1, and Pbk were upregulated in NV HSC while downregulated in NA10hd HSC (Figure 5D).
20067618	0.97	Ccnb1, Ccnb2, Ccna2, Aurka, Cdca3, Cdc2a, Bub1b, Cdca8).
	0.96	Ccnb1, Ccnb2, Ccna2, Ube2c, Aurka, Cdc2a) genes, in a similar manner as seen for BLM and N-ac-AAF.
	0.90	Ccnb1, Ccnb2, Ccna2, Aurka).
17933768	0.97	Cyclin B1, Aurora A (Eg2) and c-mos mRNAs have short tails in non-mature oocytes and are polyadenylated during maturation due to cytoplasmic polyadenylation elements in their 3' UTRs, while mRNAs encoding 'household' proteins such as ribosomal protein S6 (RPS6) and glyceraldehydeposphate dehydrogenase (GAPDH) loose their poly(A) tails during maturation.
	0.96	cyclin B1, and the kinases c-mos and Aurora A get polyadenylated during maturation and shift to the fractions with the longer poly(A) tails.
23667535	0.97	Aurora A, Cyclin B1 and Nusap1 (Fig. 5A).
25106428	0.97	Aurora-A also drives cell cycle progression by promoting cyclin B1, Wnt, myc and other pro-proliferative pathways.
29050212	0.97	Aurora kinase A (Aurka), Centromere protein H (Cenph), RAD51 recombinase (Rad51), Cyclin B1 (Ccnb1), Transcription factor Dp-2 (Tfdp2), and Myosin heavy chain 10 (Myh10)] were detected in the spleens of Rag-2 KO mice than in those of RAG-2 bKO pigs.
24983972	0.96	Aurora kinase A activity impairs neither cyclin B1 mRNA polyadenylation nor its translation and that Aurora kinase A is unlikely to be involved in CPEB1 activating phosphorylation.
	0.94	Aurora Kinase A Is Not Involved in CPEB1 Phosphorylation and cyclin B1 mRNA Polyadenylation during Meiotic Maturation of Porcine Oocytes
	0.94	Aurora kinase A inhibition on poly(A)-tail extension of long and short cyclin B1 encoding mRNAs as markers of CPEB1-dependent cytoplasmic polyadenylation.
	0.93	AURKA activity and the cyclin B1 mRNA cytoplasmic polyadenylation and expression.
	0.88	cyclin B1 mRNA is not affected by AURKA inhibition
	0.82	Cyclin B1 mRNA polyadenylation and cyclin B1 expression after AURKA inhibition.
	0.81	cyclin B1 mRNA polyadenylation and the role of AURKA in this process, we inhibited AURKA kinase activity in oocytes by adding MLN8237 at different concentrations ranging from 1 to 10 microM to the cultivation medium.
18347064	0.96	cyclin B1 S126 phosphorylation and suppressed the separation of centrosomes in prophase (Fig. 1 D), whereas activation of Aurora A was still observed by monitoring T288 phosphorylation (not depicted).
24586935	0.95	Aurka and Bub1), cell cycle progression (Cyclin A, Cyclin B1, Anapc5, c-myc and c-myb) and apoptosis (Birc5, Brca1).
25808367	0.92	Ccnb1, Mki67 and Aurka represent the top eight cell cycle expression network members.
24920883	0.91	Ccnb1, Cdc25c, Cep55, Mastl, Cdkn3, Kif2c, and Plk1), cellular signaling genes (Rhob, Nek2, Taok1, Aurka, and Arhgef12), and transcription regulation genes (Tceal1, Depdc1a, and Atf7ip2), all of which are mainly responsible for cell growth and differentiation.
30942456	0.88	AURKA, B-cell lymphoma 2 (Bcl-2), cyclin-dependent kinase 1, cyclin B1, proliferating cell nuclear antigen and heterogeneous nuclear ribonucleoprotein K, as well as the phosphorylation of p53 and mouse double minute 2 homolog, were significantly decreased in Huh-7 cells treated with 5 micromol/l cinobufagin for 24 h. Conversely, the expression levels of Bcl-2-associated X protein, p21, p53 upregulated modulator of apoptosis and phorbol-12-myristate-13-acetate-induced protein 1, were significantly increased by cinobufagin treatment.
31475039	0.88	AURKA, RRM2, CCNB1, KIF4A, CEP55, and PBK) had a significant impact on survival and belonged to the CIN signature as reported in the literature.
20661276	0.87	Aurka, Brca2, Ccnb1, Ccna2, Cenpo, Mcm7, Pbk, Prim1 and Suv39h1).
	0.72	Aurka, Brca2, Ccna2, Ccnb1, Cenpo, Mcm7, Pbk, Prim1 and Suv39h1).
22811580	0.87	CyclinB1 was used as a marker of G2/M. There was an increase in cyclinB1 in the nucleus and cytoplasm of cells from MLN8237 treated xenograft samples as compared to vehicle, supporting the idea that the AURKA inhibitor caused tumor cells to stall in G2/M. Consistent with G2/M arrest xenografts treated with MLN8327 contained numerous enlarged cells with multiple nuclei, as observed with propidium iodide (Fig. 5B).
30069007	0.63	Aurora A, Aurora B, and Cyclin B1 and Cyclin B2, among others.