Publication for Me1 and Scd1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Me1	malic enzyme 1, NADP(+)-dependent, cytosolic	17436			[link]
mmu	Scd1	stearoyl-Coenzyme A desaturase 1	20249

Pubmed ID	Priority	Text
24732937	0.98	Me1, Fasn, Scd1 and Dgat2), inflammation (Ccl2, Tnfalpha) and retinol metabolism (Rbp4, Rdh11) were down-regulated in visceral adipose tissue of HF-fed pregnant, compared with HF non pregnant mice.
	0.98	Me1, Fasn and Scd1) were down regulated by HF feeding independently of pregnancy in visceral fat (Figure 4A-C).
	0.98	Me1, Fasn, Scd1 and Dgat 2 (Figure 7B-E).
26350747	0.98	Scd1, and Me1) and fatty acid uptake (Ldlr, Cd36).
	0.98	Me1), and stearoyl-Coenzye A desaturase 1 (Scd1), was significantly decreased by UDCA-feeding in female, but not male, mice (Fig. 3A).
	0.98	Me1, and Scd1) and lipid uptake (Cd36 and Ldlr).
27042269	0.98	Me1, Scd1, Fads2) in the UCP2-/- mice were significantly upregulated.
	0.97	Me1, Scd1 and Fads2) in the PPAR signaling pathway were upregulated according to the RT-qPCR assay, which was consistent with the gene array.
	0.71	Me1 (malic enzyme 1), Scd1 (stearoyl-CoA desaturase 1) and Fads2 (fatty acid desaturase 2).
25703193	0.98	Scd1, Pdk4, Elovl5, Fgf21, Igfbp1, PPARgamma and Me1).
	0.96	Scd1, Pdk4, Elovl5 and Me1 are suppressed in both male 11 week and female 36 week Cyp1b1-ko mice on the HFD.
25998209	0.98	Me1, G6pdx), lipid synthesis (Scd1, Gpam, Fasn) and lipid sequestration (Plin2) (Fig. 4E).
	0.97	Me1, Pygl, G6pdx), lipid synthesis (Srebp1c, Scd1, Elovl3, Elovl5, Elovl6, Gpam, Acss2, Acss3, Fasn) and lipid sequestration (Plin2, Fitm1, Cidec), were all increased (Fig. 3D).
27036855	0.98	Scd1, Elovl5, Pdk4 and Me1, indicate a shift to increased fatty acid oxidation.
	0.80	Scd1, Pdk4 and Me1) that have much lower expression on the HFD, but are not further suppressed when Cyp1b1-deletion is combined with this diet.
19949424	0.98	Mod1), stearoyl CoA desaturase (Scd1) and elongation of very long-chain FAs (Elovl3) 2.67- to 3.32-fold, which may have a role in the biosynthesis of unsaturated FA and long-chain FA (Figure 3 and Table 1).
20003344	0.98	Me1 and Scd1 are known as target genes of PPARalpha responsible for important parts of lipogenesis.
22208362	0.98	SCD1, ME1, FADS2) and in cholesterol metabolism (CYP7A1, CYP8B1, LXRa and CYP27) were increased in POKO compared to ob/ob islets (Figure 2).
23396211	0.98	malic enzyme 1 (Me1), acetyl CoA carboxylase (Acaca), and stearyl CoA desaturase 1 (Scd1) (Fig. 5f).
30462643	0.98	Me1, Elovl6 and Scd1.
31589598	0.98	malic enzyme 1 (Me1), and stearoyl-coA desaturase-1 (Scd1).
30464239	0.97	ME1), acetyl-CoAcarboxylase (ACACA), and stearoyl-CoA desaturase 1 (SCD1) in the HFD-fed group compared to that in the HFD control group (Fig. 3D).
	0.73	ME1, ACACA, and SCD1 (D) and PPARalpha, PPARgamma, CD36, FABP4, and LPL (E) in mice fed a HFD ad libitum.
30692526	0.97	Scd1, Srebf1, Me1) only tended to be higher in HFD-fed Napepld IEC mice, without changes in the phosphorylation status of AMPK whereas Napepld IEC mice exhibited an increased expression of hepatic and intestinal lipid transporters.
	0.94	Scd1, Srebf1, Me1, Gpam, and Dgat2 (Supplementary Figure 4A), and no changes in genes involved in lipid oxidation such as Ppargc1a, Ppara, Cpt1a, Acox, and Acadm (Supplementary Figure 4B).
24983750	0.97	stearoyl-coenzyme A desaturase 1 (Scd1), acetyl-coenzyme A carboxylase beta (Acacb), NADP-dependent malic enzyme 1 (Me1), and elongation of very long chain fatty acids (Elovl5), were upregulated in the DMSe mice.
26933443	0.96	Scd1, Fasn, Srebf1, and Mod1 (fatty acid synthesis), as well as Gpam and Elovl6 (fatty acid storage and elongation).
30211334	0.59	malic enzyme 1 (Me1), fatty acid synthase (Fasn), and stearoyl-coenzyme A desaturase 1 (Scd1).