Publication for Mcm3 and Mcm5

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Mcm3	minichromosome maintenance complex component 3	17215			[link]
mmu	Mcm5	minichromosome maintenance complex component 5	17218

Pubmed ID	Priority	Text
22362746	0.99	MCM3 acts as a negative regulator of the MCM2-7 helicase in vivo by complexing with MCM5 in a manner dependent upon a nuclear-export signal-like domain, blocking the recruitment of MCMs onto chromatin.
	0.98	MCM3 interacts with XPO1 and MCM5 via an NES motif that is essential for inhibiting MCM chromatin binding and cell proliferation.
	0.98	MCM3 S/T sites was reported to stimulate its binding to other MCMs (including MCM5 and MCM7) and loading onto chromatin, MCM3S5A maintained strong interactions with MCM5 and MCM7 despite having mutations of these same S/T sites (Figure 4F).
	0.98	MCM3:MCM5 interaction blocks MCM2-7 loading onto chromatin in vivo, and that alteration of MCM3 levels has phenotypic consequences in parallel with the effects upon MCM loading.
	0.97	MCM3 interaction with MCM5 via a leucine-rich motif correlates with chromatin-bound MCM levels
	0.97	MCM5 and/or XPO1 specifically obliterates the negative regulatory role of MCM3.
	0.97	MCM3, we suggest that free MCM3 and/or MCM3:MCM5 decreases the amounts of their adjacent partners (MCM7 and MCM5 for MCM3; MCM2 and MCM3 for MCM5) that are available for heterohexamer formation.
	0.96	MCM3:MCM5-containing complex.
	0.94	MCM3 and MCM7 compared to MCM3 and MCM5 (Figure 4F).
25805971	0.99	Mcm3, Mcm5, Mcm6, Cdca2 and Cdca7, with many of them being repressed by Pax6.
29051483	0.98	Mcm3 and Mcm5 expression and enabling S-phase entry.
	0.98	Mcm3, and Mcm5, are important for folate-dependent de novo thymidylate biosynthesis and DNA replication.
	0.98	Mcm3 and Mcm5 have been implicated in the regulation of S phase entry (Fig. 4c).
	0.98	Mcm3 and Mcm5 (Fig. 5b), with evolutionarily conserved GABP-binding elements identified within these regions (Fig. 5c).
	0.98	Mcm3 and Mcm5 promoters in both CD4+ and CD8+ T cells (Fig. 5d).
	0.98	Mcm3 and Mcm5 proteins was observed in WT cells following T-cell activation, expression of these proteins was greatly attenuated in GABPalpha-null T cells (Fig. 5e).
	0.97	Mcm3 and Mcm5, but this induction was diminished in GABP-deficient T cells (Fig. 4c).
	0.68	Mcm3 and Mcm5 genes in WT CD4+ T cells and CD8+ T cells.
15598610	0.98	MCM3, MCM4, MCM5, ORC1, ORC6, RRM1, RRM2) and genes required for postreplicative phases of the cell division cycle (e.g., CCNB1, PLK1) are coordinately induced and reach maximal expression levels between 8 and 24 hr (Figure 6B), consistent with the timing of the histologic changes observed in Figure 6A.
21185283	0.98	Mcm3, Mcm4, Mcm5, Mcm7, Mcm8).
22046353	0.98	Mcm3, Mcm4, Mcm5, and Mcm7) are up-regulated in polyploid decidual cells (Table S3).
29125738	0.98	Mcm3, Mcm5, and Mcm6), and the 14-3-3 protein family (Ywhae, Ywhag, and Ywhab).
30246716	0.98	mcm3, mcm4, mcm5, mcm6, and mcm7), and proliferation cell nuclear antigen (PCNA) were significantly upregulated in ATF3-overexpressing CFs [Figure 3a].
30574148	0.98	MCM5 with the STAT1 C-terminal TAD and IFNgamma-induced association of MCM5 and MCM3 with the promoter and intergenic regions of Irf1, suggesting that MCM2-MCM7 complexes move along with Pol II during Irf1 transcript elongation possibly unwinding DNA through their helicase activity.
28641940	0.97	MCM3, MCM4, MCM5, MCM6 and MCM7 (thereafter called MCM2-7) are loaded onto DNA to license replication origins.
22916088	0.96	Mcm3, Mcm5, Mcm6, Mcm7), decreased from E17.5 to PN0, Figure 3F.
31443434	0.96	Mcm3, Mcm4, Mcm5, Mcm6, Mcm7) and Origin Recognition Complex (ORC) family genes (Orc1, Orc2, Orc3, Orc4, Orc6) (Figure 5C) had the same expression trend as Cdk or Cdc family genes.