Publication for Lss and Idi1

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Lss lanosterol synthase 16987 [link]
mmu Idi1 isopentenyl-diphosphate delta isomerase 319554

Pubmed ID Priority Text
22441164 0.98 IDI1, FPPS, SQLE, and LSS was significantly decreased in WY-14,643-treated vs. control mouse liver (Fig. 4D).
0.98 IDI1, FPPS, SQLE, LSS, SREBP-2) and ER stress markers (e.g., Grp78, TRIB3, ATF4, CHOP, p8) is already increased in livers from embryonic day 18.5 SW/129 Pex2-/- mice compared to controls (W.J. Kovacs and P.L. Faust, unpublished results).
0.97 IDI1, SQS, squalene epoxidase (SQLE), lanosterol synthase (LSS), 7-dehydrocholesterol reductase (DHCR7), LDL receptor (LDLR) and Insig-1 were all significantly increased 1.6- to 4.7-fold in P0 129 Pex2-/- versus control mouse liver.
25102070 0.98 lanosterol synthase (Lss), isopentenyl-diphosphate delta isomerase 1 (Idi1), and methylsterol monooxygenase 1 (Sc4mol) ( Figure 6B top left panel).
28725049 0.98 isopentenyl-diphosphate delta isomerase (IDI1), insulin induced gene-1 (INSIG-1), lanosterol synthase (LSS), mevalonate pyrophosphate decarboxylase (MVD), the low density lipoprotein receptor (LDLR) and squalene epoxidase (SQLE) were all enhanced in the absence of calreticulin (Fig. 1D).
19650929 0.97 isopentenyl-diphosphate delta isomerase (Idd1), Cyp51, lanosterol synthase, mevalonate (diphospho) decarboxylase, and sterol-C4-methyl oxidase-like (Sc4mol).
30069000 0.97 Idi1, Lss, Mvd, Mvk, Msmo1, Nsdhl, Pmvk, Sc5d, Sqle, and Tm7sf2 were significantly decreased in HFD livers.
23139832 0.96 Lss (-1.22), Sc5d (-1.34), and Idi1 (-1.58) were direct targets of SREBF1 and 2 (Fig. 3A).



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