Publication for Cyp51 and Lss

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Cyp51	cytochrome P450, family 51	13121			[link]
mmu	Lss	lanosterol synthase	16987

Pubmed ID	Priority	Text
30302725	0.98	Lss, Cyp51, Lbr, and Tm7sf2 transcriptionally changed significantly upon DOT1L deletion in vivo (Fig. 2f).
	0.98	Lss, Cyp51, and Cdkn1a, H3K79me2 levels changed upon DOT1L inhibition in cultured CGN, indicating a direct DOT1L effect (Fig. 4g-k).
	0.96	Lss, Cyp51), and in cell cycle (Cdkn1a) (summarized in supplementary in Table S1).
	0.94	Lss and Cyp51 decreased in Dot1l-cKOAtoh1 compared to that in control animals.
	0.89	Lss, Cyp51), signaling (Tnfaip8l3, B3galt5), transcription (Otx1), cell cycle (Cdkn1a), calcium-dependent cell adhesion or exocytosis (Pcdh17, Cadps2), and unclassified functions (Fam174b).
	0.85	Lss, Cyp51), cell cycle (Cdkn1a), calcium-dependent cell-adhesion or exocytosis (Pcdh17, Cadps2), and unknown function (Fam174b).
22962999	0.98	lanosterol synthase (LSS), the mRNA expression level of key enzymes involved in cholesterol biosynthesis, including HMG-CoA synthase (HMGCS), farnesyl diphosphate synthase (FDPS), and lanosterol 14alpha-demethylase (CYP51), tended to be increased by fucoxanthin.
27878435	0.98	CYP51A1-PPI network reveals an enrichment for sterol biosynthetic process (GO:0016126) categories that includes 15 protein-protein interaction candidates, namely, TM7SF2, MVD, HMGCR, HSD3B7, HMGCS1, LSS, FDFT1, DHCR7, HSD17B7, NSDHL, DHCR24, FDPS, SIGMAR1, SQLE, MVK, that are expressed in the lens.
30069000	0.98	Cyp51, Dhcr7, Fdft1, Fdps, Hmgcr, Hmgcs1, Hsd17b7, Idi1, Lss, Mvd, Mvk, Msmo1, Nsdhl, Pmvk, Sc5d, Sqle, and Tm7sf2 were significantly decreased in HFD livers.
30271348	0.98	Lss (lanosterol synthase), Dhcr24 (24-dehydrocholesterol reductase), Cyp51, Nsdhl (NAD(P) dependent steroid dehydrogenase-like), Hsd17b7, Ebp, Sc5d, and Dhcr7] exhibited reduced expression compared to ad libitum mice (Figure 8A).
19650929	0.97	lanosterol synthase, Cyp51, and steroidogenic acute regulatory protein (Star).
	0.97	Cyp51, lanosterol synthase, mevalonate (diphospho) decarboxylase, and sterol-C4-methyl oxidase-like (Sc4mol).
21781316	0.97	Lss, Cyp51, Sc5d).
29367259	0.96	lanosterol synthase and CYP51 protein expression.
	0.91	LSS and CYP51 protein levels (Fig. 3E).
31998465	0.96	CYP51, MSMO1, DHCR7, DHCR24, LSS, NSDHL).
28258022	0.94	LSS, LBR, NSDHL and CYP51), for example, showed them to be more highly adducted in the a-7-DHC experiment than was found in experiments with a-Lan, see Fig. 1 for the protein function and Fig. 5C for relative enrichment.
30046109	0.92	lanosterol synthase with Ro 48-8071 abrogated the enhanced oligodendrocyte formation observed from the CYP51 inhibitor ketoconazole.
25393872	0.72	Lss and Ebp from cholesterol synthesis (Table S5), which is in line with Gatti et al and relates well with Lorbek et al. However, in our study we investigated sexual dimorphism in context of Cyp51 genotype and we uncovered novel differences at the level of expression of cholesterogenic genes.
32123859	0.66	CYP51A1and LSS, and a twofold increase in SREBP2 protein levels in lapatinib treated tumors compared to control tumors [Figure 5C (CYP51A1), 5D (LSS), and 5E (SREBP2)].
	0.55	CYP51A1, LSS, and DHCR24 in both control and lapatinib treated LLC mouse tumors (Figure 5B).