Publication for Lamp1 and Mfsd1

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Lamp1 lysosomal-associated membrane protein 1 16783 [link]
mmu Mfsd1 major facilitator superfamily domain containing 1 66868

Pubmed ID Priority Text
31661432 0.99 MFSD1 was previously shown to co-localize with LAMP1 or LAMP2, respectively, indicating that it is a resident lysosomal protein.
0.98 MFSD1 with LAMP1 validated the lysosomal localization at the endogenous level (Figure 1C) and notably MFSD1 was absent from Golgi-apparatus structures.
0.98 MFSD1 in the lysosome-enriched fraction similar to the striking enrichment of the lysosome-marker LAMP1 (Figure 1D).
0.98 MFSD1 in Glmp KO MEFs followed by immunofluorescence staining for HA and LAMP1 revealed predominantly co-localization between MFSD1 and LAMP1, indicating proper sorting to lysosomes (Figure 6E).
0.98 MFSD1-HA with GLMP, but not LAMP1, significantly reduced the formation of these proteolytic fragments, indicating that specifically GLMP is able to protect MFSD1 from proteolysis (Figure 6G).
0.97 MFSD1 with LAMP1 in Glmp KO MEFs, while HA-tagged LAMP1, used as a negative control, did not rescue MFSD1, indicating a critical interdependence of GLMP and MFSD1.
0.97 MFSD1-HA alone and co-transfection with LAMP1 leads to the generation of N- and C-terminal proteolytic fragments (see also Figure 1B).
0.93 MFSD1 shows extensive co-localization with LAMP1 in lysosomes of wildtype MEFs, MFSD1 staining was absent in Mfsd1 KO MEFs validating the specificity of the staining.
0.70 MFSD1 in Glmp KO MEFs notably did not co-localize with LAMP1, but with the Golgi marker GM130.



The preparation time of this page was 0.0 [sec].