Publication for Lamp1 and Mfsd1
Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
---|---|---|---|---|---|---|
mmu | Lamp1 | lysosomal-associated membrane protein 1 | 16783 | [link] | ||
mmu | Mfsd1 | major facilitator superfamily domain containing 1 | 66868 |
Pubmed ID | Priority | Text |
---|---|---|
31661432 | 0.99 | MFSD1 was previously shown to co-localize with LAMP1 or LAMP2, respectively, indicating that it is a resident lysosomal protein. |
0.98 | MFSD1 with LAMP1 validated the lysosomal localization at the endogenous level (Figure 1C) and notably MFSD1 was absent from Golgi-apparatus structures. | |
0.98 | MFSD1 in the lysosome-enriched fraction similar to the striking enrichment of the lysosome-marker LAMP1 (Figure 1D). | |
0.98 | MFSD1 in Glmp KO MEFs followed by immunofluorescence staining for HA and LAMP1 revealed predominantly co-localization between MFSD1 and LAMP1, indicating proper sorting to lysosomes (Figure 6E). | |
0.98 | MFSD1-HA with GLMP, but not LAMP1, significantly reduced the formation of these proteolytic fragments, indicating that specifically GLMP is able to protect MFSD1 from proteolysis (Figure 6G). | |
0.97 | MFSD1 with LAMP1 in Glmp KO MEFs, while HA-tagged LAMP1, used as a negative control, did not rescue MFSD1, indicating a critical interdependence of GLMP and MFSD1. | |
0.97 | MFSD1-HA alone and co-transfection with LAMP1 leads to the generation of N- and C-terminal proteolytic fragments (see also Figure 1B). | |
0.93 | MFSD1 shows extensive co-localization with LAMP1 in lysosomes of wildtype MEFs, MFSD1 staining was absent in Mfsd1 KO MEFs validating the specificity of the staining. | |
0.70 | MFSD1 in Glmp KO MEFs notably did not co-localize with LAMP1, but with the Golgi marker GM130. |
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