Publication for Got1 and Got2

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Got1	glutamic-oxaloacetic transaminase 1, soluble	14718			[link]
mmu	Got2	glutamatic-oxaloacetic transaminase 2, mitochondrial	14719

Pubmed ID	Priority	Text
29657030	0.98	GOT2 (130%), AGC1 (66%), and GOT1 (97%) in COX10 KO muscle (Fig. 7I, 7E, 7H, 7J), suggesting that alphaKG-derived OAA exits the TCA cycle and is transaminated and transported as aspartate into the cytosol, similarly to mtDNA mutant cells in culture (Fig. 4E, 7D).
	0.98	GOT1, and GOT2 were unchanged in muscle of COX10 KO mice at 50 days of age (Fig. S7F), an early stage of myopathy, indicating that changes in the expression of these enzymes were dependent on the stage of disease progression.
	0.95	GOT1 were also significantly increased in A6MT cells compared to WT (95% increase, Fig. 6B, 6D), whereas no difference was found in GOT2 protein levels (Fig. 6B, 6D).
	0.94	GOT1 mRNA was significantly increased (30%) in A6MT cells compared to WT, while no differences were detected in GOT2 mRNA levels (Fig. S6A).
31217581	0.98	Got1 and Got2, suggesting the malate-aspartate shuttle is critical during Th1 cell activation (Fig. 3b).
	0.93	Got1 and Got2, respectively.
26383514	0.98	GOT1, GOT2 and malate dehydrogenase 1 (MDH1), which control levels of aspartate and glutamate, suggesting further mechanisms in neuroprotection.
28811348	0.98	GOT1 and GOT2, respectively), were upregulated (Fig. 3A).
30122555	0.98	Got1 and Asns), but not in the mitochondria (Got2), is upregulated in low-glutamine conditions (Figure S5C).
30392958	0.97	GOT1 and GOT2 and is converted to alpha-KG by glutamate dehydrogenase 1 (GLUD1), which are each expressed in CD4 and CD8 T cells (Figure S1A).
24973316	0.96	GOT1 and GOT2 mRNA was unchanged during both miR-122 overexpression and silencing, whereas the ALT (GPT) enzymatic activity in cell lysates showed a significant increase when cells were transfected with the miR-122 mimic.
26276101	0.96	GOT1) and mitochondrial (GOT2) isoforms (Fig. 1A).
29221133	0.96	GOT1 and GOT2, respectively (Figure 2).
29988084	0.96	Got1, Got2, and Gnao1) and "synaptic vesicle cycle" (Stx1a, Ppp3ca, Nsf, and Dnm1).
31213966	0.96	GOT1 and GOT2) and the mitochondrial malate dehydrogenase (MDH2) are decreased compared to wild-type controls (; Figure 2B).
28105457	0.94	Got1, Got2) (Supplementary Figure 1).
29254681	0.88	GOT1 and GOT2 and a downregulation of GLUD1.
26114427	0.75	GOT2) (catalyzes oxaloacetate to Asp in mitochondria) was upregulated by 4.1-fold, Slc25a13 (a transporter of Asp) by 10.7-fold, GOT1 (Asp to oxaloacetate in cytosol) by 4.4 fold, malate dehydrogenase 1 (oxaloacetate to malate in cytosol) by 4.4-fold, Slc25a11 (a transporter of malate) by 2.2-fold, and malate dehydrogenase 2 (malate to oxaloacetate in mitochondria) by 2.3-fold.
25287256	0.72	Got1 and mitochondrial Got2 (Kim et al.).