Publication for Cyp51 and Dhcr7

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Cyp51	cytochrome P450, family 51	13121			[link]
mmu	Dhcr7	7-dehydrocholesterol reductase	13360

Pubmed ID	Priority	Text
22394543	0.98	Cyp51, Nsdhl, Tm7sf2, Dhcr7, Hsd17b7) were found consistently upregulated in the intestinal tissue.
	0.97	Cyp51 and Dhcr7 were significantly upregulated in mice on the Western diet when compared to the control group.
	0.97	Cyp51), the 7-dehydrocholesterol reductase (Dhcr7), the hydroxysteroid (17-beta) dehydrogenase 7 (Hsd17b7), the NAD(P) dependent steroid dehydrogenase-like (Nsdhl) and the transmembrane 7 superfamily member 2 (Tm7sf2) genes.
	0.97	Cyp51 and Dhcr7 in liver samples of the mice fed the Western diet, suggesting that hepatic cholesterol synthesis is increased as well.
31676775	0.98	Dhcr7, Sqle, and Cyp51, suggest that, overall, TCDD exposure is repressing cholesterol biosynthesis in mice of both sexes.
	0.97	Dhcr7, Sqle, and Cyp51 were significantly increased as compared to TCDD alone in females while Dhcr7 and Sqle was significantly increased in males.
	0.96	Dhcr7), squalene epoxidase (Sqle), and Cytochrome P450, family 51 (Cyp51) (Table 1).
27878435	0.98	CYP51A1-PPI network reveals an enrichment for sterol biosynthetic process (GO:0016126) categories that includes 15 protein-protein interaction candidates, namely, TM7SF2, MVD, HMGCR, HSD3B7, HMGCS1, LSS, FDFT1, DHCR7, HSD17B7, NSDHL, DHCR24, FDPS, SIGMAR1, SQLE, MVK, that are expressed in the lens.
	0.97	CYP51A1, CYP27A1, SC5D, DHCR7 genes clearly suggest their role in sterol biosynthetic process/pathways.
22252456	0.98	Cyp51, and Dhcr7).
25393872	0.98	Cyp51+/- mice even if different genes show statistical significance in males and in females - the overexpression of Nsdhl and Dhcr7 in females and again Dhcr24 in males (Figure S2 B).
30069000	0.98	Cyp51, Dhcr7, Fdft1, Fdps, Hmgcr, Hmgcs1, Hsd17b7, Idi1, Lss, Mvd, Mvk, Msmo1, Nsdhl, Pmvk, Sc5d, Sqle, and Tm7sf2 were significantly decreased in HFD livers.
30271348	0.98	Cyp51, Nsdhl (NAD(P) dependent steroid dehydrogenase-like), Hsd17b7, Ebp, Sc5d, and Dhcr7] exhibited reduced expression compared to ad libitum mice (Figure 8A).
30463396	0.98	cytochrome P450 family 51 subfamily A polypeptide 1 (CYP51A1), acyl-CoA synthetase short-chain family member 2 (ACSS2), and 7-dehydrocholesterol reductase (DHCR7).
30735525	0.98	cytochrome P450 family 511 (Cyp51), 7-dehydrocholesterol reductase (Dhcr7), and cholestenol delta-isomerase (Ebp) were remarkably decreased by treatment with PD153035 (Fig 4C).
25556834	0.97	DHCR7, and CYP51 are observed in HD human and other mouse models.
	0.96	lanosterol 14alpha-demethylase (CYP51), and 7-dehydrocholesterol reductase (DHCR7) (Figures 3C-F; Figures S3 C-F).
19183246	0.97	CYP51, DHCR7, DHCR24, FDFT1, FDPS, IDI1, NSDHL and SQLE are members of the mevalonate pathway downstream of the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and represent potent therapeutic targets for cholesterol-lowering agents.
21781316	0.97	Dhcr7) and the DDAH mice (Hmgcs1, Fdps, Mvk, Dhcr7, Lss, Cyp51, Sc5d).
31998465	0.96	CYP51, MSMO1, DHCR7, DHCR24, LSS, NSDHL).
31618976	0.78	Cyp51), and Dhcr7 expressions were found to be similar in both liver genotypes at all 3-time points (Figure 6e).