Publication for Cct6a and Cct8

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 12466 [link]
mmu Cct8 chaperonin containing Tcp1, subunit 8 (theta) 12469

Pubmed ID Priority Text
26321202 0.98 CCT6A, CCT7, CCT8), as well as protein disulfide isomerases that modulate protein folding (PDIA3, PDIA6) in the Type I SMA MNs (Figure 2F), suggesting the activation of the UPR pathway in these MNs.
19661457 0.97 CCT6, CCT8, TCP1) recognize misfolded proteins in the cytosol and because of their barrel-like structure, create a favorable environment for protein refolding.
30632495 0.97 CCT6 and CCT8 also increased the level of ptau, which points towards an effect on ptau by CCT that is not subunit specific.
23038063 0.92 CCT6A, CCT8), cell cycle regulation (CAPRIN1, GNB2L1, CGREF1, DTYMK, PCNP) and mitochondrial function (SND1, CHCHD3, PDSS, SLC25A39) (supplementary material Table S5).



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