Publication for Gart and Mthfd1
Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
---|---|---|---|---|---|---|
mmu | Gart | phosphoribosylglycinamide formyltransferase | 14450 | [link] | ||
mmu | Mthfd1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase | 108156 |
Pubmed ID | Priority | Text |
---|---|---|
29732722 | 0.97 | Mthfd1 and Gart have lower expression levels in FA-resistant mutants, even in the presence of FA supplementation, the de novo purine biosynthesis probably is still insufficient to rescue the FA-resistant mutants by promoting proper NTC. |
0.96 | Mthfd1 and Gart are involved in de novo purine biosynthesis. | |
0.84 | Mthfd1, Gclc, Gart, and Abcc3 all have lower expression levels in at least two FA-resistant mutants; while Slc44a2, Slc25a32, and Bche have higher expression levels in at least two FA-resistant NTD mutants. | |
0.66 | Mthfd1, Gart, Bche, Slc25a32, and Slc44a2) were identified by examining the DEGs of those genes involved in the extended folate metabolic pathway between FA-responsive and FA-resistant mutants. | |
29979702 | 0.92 | MTHFD1, MTHFD2, GART, ATIC, MTRR, and DHFR. |
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