Publication for Aurka and Cdc20

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Aurka	aurora kinase A	20878			[link]
mmu	Cdc20	cell division cycle 20	107995

Pubmed ID	Priority	Text
25628462	0.98	AURKA, CDC20 and BUB1 (all mediators of the G2/M transition) further support its role in promoting the G2/M transition.
	0.98	AURKA, CDC20 and BUB1 (Fig. 6).
27165742	0.98	Cdc20, Cdc25c, Aurka and Myc were dramatically increased in the Olig2-expressing Ctrl-T tumors compared with the wild-type corpus callosum (Figure 6I).
	0.97	Cdc20, Cdc25c, along with cell proliferation-promoting factors Aurka and Pim1 (Figures 6G and 6H).
20956380	0.98	aurora A, and aurora B. APC/C has two activating subunits, Cdc20 and Cdh1, which function in substrate recruitment and are thought to induce changes in APC/C conformation that increase activity.
22363607	0.98	Aurka (aurora kinase A), Aurkb, Cdc6, Cdc7, Cdc20 and Cdc25b), and transcripts involved in DNA synthesis and replication (Rrm2 (ribonucleotide reductase M2), Lig1 (ligase 1) and Top2a (DNA topoisomerase II alpha)) were enriched in the fetal liver.
24478334	0.98	Aurka, Aurkb, Cdc2 and Cdc20.
25249570	0.98	aurora A kinase (Aurka), cell division cycle 20 (Cdc20), and cyclin A2 (Ccna2) are upregulated by YAP.
25305307	0.98	Aurka, Cdc20, Cnnb1, and Cdc5l were all increased in the DKO hearts (Fig. 3F) consistent with increased cell cycle activity in the absence of alpha-catenins.
26387737	0.98	Aurora A, Aurora B, Cyclin B1, Cdc20, and UbcH10.
27785155	0.98	Aurka, Birc5, Bub1b, Cdc20, Meox1, Pbk, Kif22, Mcm5, Mcm6, Ncaph, Plk1, Ung, and Cdca3 were overexpressed (Fig. 3b), indicating that developmental cellular processes were still abundant in the kidneys of CON 1W.
27720608	0.97	Aurka and Cdc20, as well as the canonical TEAD-YAP target gene Ctgf, was reduced in P12 hearts treated with AAV9.VGLL4[R], compared with AAV9.GFP (Figure 6G).
	0.58	Aurka, Cdc20, and Ctgf in P12 heart.
21440680	0.96	Cdc20, Cdca8, Cdca3, Cdc45l, Cdca7l), cyclin-dependent kinases (Cdk4, Cdk2), and mini-chromosome maintenance proteins (Mcm2, Mcm6, Mcm5, Mcm4, Mcm7, Mcm10), among other genes that regulate cell division dynamics, such as Mki67, Aurka, Aurkb, Hmgb2, Smc2, Birc5, and Prc1 (Figures 5, 5b, 5c, 5d).
25189354	0.96	Aurora Kinase A (Aurka, required for G2-M transition) and Cell Division Cycle Protein 20 (Cdc20, activates anaphase promoting complex).
27207783	0.96	Cdc20, Aurka, Bub1, Mad2l1, Aurkb, and Bub1b were downregulated by 2.1-, 1.9-, 1.7-, 1.7-, 1.6-, and 1.6-fold, respectively, in descending colon.
22014574	0.95	CDC20 are essential E3-ligases of the APC/C complex, which serve as co-activators for APC/C and have substrate specificity for different APC/C substrates, including Aurora-A. Given our earlier observation that SIRT2 overexpression mediated Aurora-A degradation is blocked by proteosome inhibitor MG132 (Figure 3I), we hypothesized that SIRT1 might modulate Aurora-A stability through interacting with CDH1 and CDC20.
26427040	0.95	Stk6 (Aurora-A kinase), Cks1 (cdc28 protein kinase), Cks2 (cdc28 protein kinase regulator subunit 2), cdc20, regulators of cytokinesis Prk1 (protein 1) as well as kinesin family members.
32160703	0.95	Aurka, Cdc20, and Igf2 exhibited a marked upregulation (i.e., 137-fold, 262-fold, and 1,034-fold change, respectively).
23288605	0.94	Aurka, Birc5, Brca2, Bub1b, Ccnd1, Ccnd3, Cdc20, Cdca2, Cdca5, Cdt1, E2f8, Fbxo5, Gmnn, Hells, Jub, Nek2, Trpt53/p53.
25808367	0.89	Cdc20, Plk1, Birc5, Cenpe, Ccnb1, Mki67 and Aurka represent the top eight cell cycle expression network members.
31475039	0.87	CDC20, TRIP13, NEK2, AURKA, RRM2, CCNB1, KIF4A, CEP55, and PBK) had a significant impact on survival and belonged to the CIN signature as reported in the literature.
29719257	0.77	Aurka, and Cdc20), (Figure S4C) DNA damage response (Lig1, Pcna, Pole, and Pttg1) (Figure S4D), and hypoxia/metabolism (Hif3a, Anxa, Aldoa, and Ldha) (Figure S4E).