Publication for Plk1 and Cdc20

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Plk1	polo like kinase 1	18817			[link]
mmu	Cdc20	cell division cycle 20	107995

Pubmed ID	Priority	Text
25628462	0.98	PLK1, CDC20 and Aurora kinase B (AURKB) (Table 1).
	0.98	PLK1, AURKA, CDC20 and BUB1 (all mediators of the G2/M transition) further support its role in promoting the G2/M transition.
	0.98	PLK1, AURKA, CDC20 and BUB1 (Fig. 6).
	0.96	PLK1, AURKB and CDC20 interact with BUB1 (budding uninhibited by benzimidazoles 1, a regulator of the spindle assembly checkpoint) during G2/M, we investigated whether BUB1 also interacted with FADD.
27785155	0.98	Cdc20, Meox1, Pbk, Kif22, Mcm5, Mcm6, Ncaph, Plk1, Ung, and Cdca3 were overexpressed (Fig. 3b), indicating that developmental cellular processes were still abundant in the kidneys of CON 1W.
	0.98	Cdc20, Ccnd1, Plk1, Bub1b, Rrm2, Mcm5, Mcm6) and cell differentiation-related molecules (Id1, Id2, Rad9, Birc5) was detected in the RES 1W group (Fig. 4c).
20065091	0.98	Cdc20, Plk1, and Aurora A and B, four substrates which are normally targeted for degradation by APC/CCdh1 later in mitosis (Fig. 5 A).
20956380	0.98	Plk1, aurora A, and aurora B. APC/C has two activating subunits, Cdc20 and Cdh1, which function in substrate recruitment and are thought to induce changes in APC/C conformation that increase activity.
25470754	0.98	Plk1 and Aurora B, the APC/C activator, Cdc20, is joined with Mad2 and BubR1/Bub3 to form the MCC, which inhibits APC/C activity.
26387737	0.98	Plk1, Aurora A, Aurora B, Cyclin B1, Cdc20, and UbcH10.
29115400	0.98	Cdc20, Ndc80, Bub1 and Plk1, may arrest prostate cancer proliferation.
29996919	0.98	polo-like kinase 1 (PLK1), cyclin B1, cyclin B2, cyclin-dependent kinase 1 (CDK1), CDC20, cell cycle phosphatases CDC25A and CDC25C, DNA replication licensing factor MCM5, CKS116 and antiapoptotic survivin (BIRC5).
25808367	0.97	Cdc20 or Plk1 have been discovered and such cell cycle expression networks show species, sex, and tissue variability.
	0.95	Cdc20 and Plk1 (www.bioinfo.vanderbilt.edu/webgestalt).
	0.91	Cdc20, Plk1, Birc5, Cenpe, Ccnb1, Mki67 and Aurka represent the top eight cell cycle expression network members.
27102006	0.97	Plk1 is a substrate of the APC/C-Cdh1 while cyclin B and securin are substrates of APC/C-Cdc20, suggesting that APC/C-Cdh1 is inactive in E1KD cells, while the APC/C-Cdc20 complex appears to be constitutively active.
	0.97	Plk1) are stabilized and APC/C-Cdc20 substrates (cyclin B and securin) are lost in E1KD cells.
18675487	0.97	Cdc20 and Polo like kinase 1 (Plk1; green).
24801167	0.97	Cdc20, polo-like kinase 1 (PLK1), centromere proteins (CENPs), E2F family members (E2F1, 4, 6), and survivin.
29222421	0.97	Polo-like kinase 1 (Plk1), cell division cycle 20 homolog (Cdc20), cell division cycle associated 3 (Cdca3) and cyclin B1 were all upregulated in liver cancers.
29596435	0.97	CDC20, PLK1, TGFB2 and TTK) played fatal roles in the development of pancreatic adenocarcinoma.
29888801	0.97	Polo-like Kinase 1, Cyclin B2, Cdc20, Cenpa, Kif20a and Cdk1) using real time PCR; all these genes were significantly downregulated at Day 1 and 2 in [MET KO + EGFRi] mice (Fig. 5C).
29623939	0.96	polo like kinase 1 [PLK1], cell division cycle 6 [CDC6]; cell division cycle 20 [CDC20], and BUB1 mitotic checkpoint serine/threonine kinase [BUB1]) and complement-related genes (including complement C3 [C3]) may be specifically altered in spinal cord of aged and young injured mice, respectively.
	0.96	PLK1 can phosphatase CDC6 (Yim and Erikson, 2010), Cdc25C (Toyoshimamorimoto et al., 2002), CDC20 (Jia et al., 2016), CCD14B (Bassermann et al., 2008), BUB1 (Qi et al., 2006), BubR1 (BUB1-related) (Elowe et al., 2007), and CDK5 regulatory subunit associated protein 2 (CDK5RAP2) (Hanafusa et al., 2015) to promote spindle checkpoint signaling.
28968996	0.96	Cdc20 to bind with APC/C. APC/CCdh1 degrades Cdc20 and other cyclins such as Aurora and Plk1 to advance the cell cycle into the G1 phase.
24880458	0.94	Cdc20, Mcm5, and Plk1:but not E2f and Ccn2:were confirmed to be more abundantly expressed in this assay (Supplementary Fig. 10 and data not shown).
25668030	0.94	Cdc20, Cdc25a, Cdc45l, Cdc6, Cdc7, Cdkn2c, Dbf4, E2f2, Espl1, Orc6l, and Plk1 were involved in cell growth as well as death.
22936984	0.93	cdc20 and plk1.
31540287	0.88	polo-like kinase 1 (PLK1)-based drug resistance in ovarian cancer cells and CDC20-based resistance in diffuse large B-cell lymphoma.
17147824	0.83	Plk1, Gadd45a, Apc11, Cdc20 and Cdkn1a) were also dysregulated.
27528194	0.79	Cdc20 is subject to two regulatory phosphorylation events that disrupt its ability to activate the APC/C. We examined the phosphorylation status of two residues of Cdc20 implicated in mediating this inhibition, S153 and S92 by Bub1 kinase and Plk1 kinase respectively, in wild-type, FL-Bub1b and Bub1bDeltaI MEFs by Western blot (Figure 6D).