[][] sce TOP2 Gene 
functional annotation
Function   DNA topoisomerase 2
GO BP
GO:0000819 [list] [network] sister chromatid segregation  (1 genes)  IBA  
GO:0097046 [list] [network] replication fork progression beyond termination site  (2 genes)  IMP  
GO:0031055 [list] [network] chromatin remodeling at centromere  (3 genes)  IMP  
GO:0000019 [list] [network] regulation of mitotic recombination  (4 genes)  IMP  
GO:0000712 [list] [network] resolution of meiotic recombination intermediates  (5 genes)  IBA  
GO:0044774 [list] [network] mitotic DNA integrity checkpoint  (6 genes)  IMP  
GO:0006271 [list] [network] DNA strand elongation involved in DNA replication  (7 genes)  IMP  
GO:0006259 [list] [network] DNA metabolic process  (8 genes)  IEA  
GO:0006265 [list] [network] DNA topological change  (10 genes)  IDA IEA  
GO:0006333 [list] [network] chromatin assembly or disassembly  (16 genes)  IMP  
GO:0007131 [list] [network] reciprocal meiotic recombination  (41 genes)  IMP  
GO CC
GO:0097047 [list] [network] DNA replication termination region  (1 genes)  IPI  
GO:0000795 [list] [network] synaptonemal complex  (9 genes)  IDA  
GO:0005739 [list] [network] mitochondrion  (915 genes)  IDA  
GO:0005634 [list] [network] nucleus  (1765 genes)  IDA IEA  
GO MF
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (2 genes)  IDA IEA  
GO:0003916 [list] [network] DNA topoisomerase activity  (3 genes)  IEA  
GO:0016853 [list] [network] isomerase activity  (60 genes)  IEA  
GO:0003677 [list] [network] DNA binding  (359 genes)  IEA  
GO:0005524 [list] [network] ATP binding  (546 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (619 genes)  IEA  
GO:0000166 [list] [network] nucleotide binding  (638 genes)  IEA  
KEGG
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2b (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)top2 (spo)
Subcellular
localization
nucl 7,  cyto 1  (predict for NP_014311.3)
Gene coexpression
Network*for
coexpressed
genes
Coexpressed
gene list
[Coexpressed gene list for TOP2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 855636    
Refseq ID (protein) NP_014311.3 


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