[][] hsa TOP2B Gene 
functional annotation
Function   DNA topoisomerase II beta
GO BP
GO:0000819 [list] [network] sister chromatid segregation  (3 genes)  IBA  
GO:0044774 [list] [network] mitotic DNA integrity checkpoint  (3 genes)  IBA  
GO:0006265 [list] [network] DNA topological change  (9 genes)  IDA  
GO:0000712 [list] [network] resolution of meiotic recombination intermediates  (15 genes)  IBA  
GO:0030900 [list] [network] forebrain development  (44 genes)  IEA  
GO:0016925 [list] [network] protein sumoylation  (76 genes)  TAS  
GO:0007409 [list] [network] axonogenesis  (94 genes)  IEA  
GO:0001764 [list] [network] neuron migration  (101 genes)  IEA  
GO CC
GO:0000792 [list] [network] heterochromatin  (21 genes)  IDA  
GO:0030529 [list] [network] ribonucleoprotein complex  (124 genes)  ISS  
GO:0005730 [list] [network] nucleolus  (839 genes)  IDA  
GO:0005654 [list] [network] nucleoplasm  (3108 genes)  IDA TAS  
GO:0005829 [list] [network] cytosol  (4875 genes)  IDA  
GO:0005634 [list] [network] nucleus  (5173 genes)  IDA  
GO MF
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (3 genes)  IDA  
GO:0043021 [list] [network] ribonucleoprotein complex binding  (32 genes)  ISS  
GO:0005080 [list] [network] protein kinase C binding  (49 genes)  IPI  
GO:0042826 [list] [network] histone deacetylase binding  (108 genes)  IPI  
GO:0008022 [list] [network] protein C-terminus binding  (185 genes)  IPI  
GO:0019899 [list] [network] enzyme binding  (333 genes)  IPI  
GO:0003682 [list] [network] chromatin binding  (369 genes)  IDA  
GO:0046982 [list] [network] protein heterodimerization activity  (497 genes)  IPI  
GO:0005524 [list] [network] ATP binding  (1477 genes)  IEA  
GO:0003677 [list] [network] DNA binding  (1486 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (2264 genes)  IEA  
KEGG hsa01524 Platinum drug resistance
Orthologous [Ortholog page] TOP2A (hsa)Top2a (mmu)Top2b (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)TOP2 (sce)top2 (spo)
Subcellular
localization
nucl 5,  cyto_nucl 4,  cyto 3  (predict for NP_001059.2)
nucl 5,  cyto_nucl 4,  cyto 3  (predict for NP_001317629.1)
nucl 4,  cyto_nucl 4,  cyto 4  (predict for XP_011532359.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
Genes directly connected with TOP2B on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
896.0 CENPC centromere protein C [detail] 1060
1134.9 BMI1 BMI1 proto-oncogene, polycomb ring finger [detail] 648
1165.1 BPTF bromodomain PHD finger transcription factor [detail] 2186
Coexpressed
gene list
[Coexpressed gene list for TOP2B]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 7155    
Refseq ID (protein) NP_001059.2 
NP_001317629.1 
XP_011532359.1 


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