[][] mcc TOP2A Gene 
functional annotation
Function   DNA topoisomerase II alpha
GO BP
GO CC
GO MF
KEGG mcc01524 Platinum drug resistance
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2b (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2 (sce)top2 (spo)
Subcellular
localization
nucl 6,  cyto_nucl 5,  cyto 4,  cyto_mito 2  (predict for XP_014975074.1)
cyto_nucl 6,  nucl 6,  cyto 4  (predict for XP_014975075.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04110 Cell cycle 3
mcc04114 Oocyte meiosis 3
mcc04218 Cellular senescence 3
mcc04115 p53 signaling pathway 2
mcc04914 Progesterone-mediated oocyte maturation 2
Genes directly connected with TOP2A on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
8.4 CCNB2 cyclin B2 [detail] 702184
21.7 NCAPG non-SMC condensin I complex subunit G [detail] 715235
36.6 LOC714349 ubiquitin-conjugating enzyme E2 C [detail] 714349
36.7 MELK maternal embryonic leucine zipper kinase [detail] 716875
37.3 DDX10 DEAD-box helicase 10 [detail] 708293
53.0 CDK1 cyclin dependent kinase 1 [detail] 699269
57.7 LOC695574 chromosome-associated kinesin KIF4A [detail] 695574
57.9 DEPDC1 DEP domain containing 1 [detail] 701888
59.5 NUF2 NUF2, NDC80 kinetochore complex component [detail] 693637
64.1 CENPF centromere protein F [detail] 709000
79.6 ASPM abnormal spindle microtubule assembly [detail] 711153
85.0 KIF23 kinesin family member 23 [detail] 695229
87.5 FOXM1 forkhead box M1 [detail] 708805
91.2 HSF4 heat shock transcription factor 4 [detail] 698412
111.1 CKAP2 cytoskeleton associated protein 2 [detail] 693531
150.0 RAD51AP1 RAD51 associated protein 1 [detail] 710918
151.6 TPX2 TPX2, microtubule nucleation factor [detail] 712961
171.5 DIAPH3 diaphanous related formin 3 [detail] 695990
210.2 SHCBP1 SHC binding and spindle associated 1 [detail] 716009
236.5 IQGAP3 IQ motif containing GTPase activating protein 3 [detail] 719575
263.8 CENPN centromere protein N [detail] 713624
267.8 SMC2 structural maintenance of chromosomes 2 [detail] 713359
274.1 CKS2 CDC28 protein kinase regulatory subunit 2 [detail] 697324
338.1 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase [detail] 722252
367.0 HELLS helicase, lymphoid specific [detail] 701598
422.4 LMNB1 lamin B1 [detail] 703575
446.1 CENPW centromere protein W [detail] 712570
509.3 PIMREG PICALM interacting mitotic regulator [detail] 712701
528.3 FANCI Fanconi anemia complementation group I [detail] 699878
638.4 PTTG1 pituitary tumor-transforming 1 [detail] 696143
668.1 ATAD2 ATPase family, AAA domain containing 2 [detail] 704478
819.4 TMSB15A thymosin beta 15a [detail] 693501
834.8 LOC702446 dihydrofolate reductase-like [detail] 702446
1089.9 ALDH9A1 aldehyde dehydrogenase 9 family member A1 [detail] 695383
1176.1 SMC4 structural maintenance of chromosomes 4 [detail] 702615
Coexpressed
gene list
[Coexpressed gene list for TOP2A]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 700707    
Refseq ID (protein) XP_014975074.1 
XP_014975075.1 


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