[][] hsa ACTC1 Gene 
functional annotation
Function   actin, alpha, cardiac muscle 1
GO BP
GO:0033275 [list] [network] actin-myosin filament sliding  (1 genes)  IMP  
GO:0090131 [list] [network] mesenchyme migration  (5 genes)  ISS  
GO:0030240 [list] [network] skeletal muscle thin filament assembly  (6 genes)  ISS  
GO:0055003 [list] [network] cardiac myofibril assembly  (11 genes)  ISS  
GO:0055008 [list] [network] cardiac muscle tissue morphogenesis  (12 genes)  ISS  
GO:0060047 [list] [network] heart contraction  (13 genes)  IMP  
GO:0030048 [list] [network] actin filament-based movement  (15 genes)  IDA  
GO:0031032 [list] [network] actomyosin structure organization  (27 genes)  ISS  
GO:0030049 [list] [network] muscle filament sliding  (38 genes)  TAS  
GO:0060048 [list] [network] cardiac muscle contraction  (45 genes)  IEA  
GO:0045471 [list] [network] response to ethanol  (103 genes)  IEA  
GO:0010628 [list] [network] positive regulation of gene expression  (314 genes)  ISS  
GO:0043066 [list] [network] negative regulation of apoptotic process  (476 genes)  IEA  
GO CC
GO:0042643 [list] [network] actomyosin, actin portion  (2 genes)  IDA  
GO:0031674 [list] [network] I band  (20 genes)  ISS  
GO:0030017 [list] [network] sarcomere  (40 genes)  IDA  
GO:0005884 [list] [network] actin filament  (61 genes)  IDA  
GO:0044297 [list] [network] cell body  (65 genes)  ISS  
GO:0030175 [list] [network] filopodium  (69 genes)  ISS  
GO:0030027 [list] [network] lamellipodium  (171 genes)  ISS  
GO:0072562 [list] [network] blood microparticle  (178 genes)  HDA  
GO:0005925 [list] [network] focal adhesion  (395 genes)  HDA  
GO:0005615 [list] [network] extracellular space  (1600 genes)  HDA  
GO:0016020 [list] [network] membrane  (1918 genes)  HDA  
GO:0070062 [list] [network] extracellular exosome  (2817 genes)  HDA  
GO:0005737 [list] [network] cytoplasm  (4013 genes)  IDA  
GO:0005829 [list] [network] cytosol  (4875 genes)  TAS  
GO MF
GO:0017022 [list] [network] myosin binding  (22 genes)  IDA IPI  
GO:0016887 [list] [network] ATPase activity  (156 genes)  IDA  
GO:0005524 [list] [network] ATP binding  (1477 genes)  IDA  
KEGG hsa04260 Cardiac muscle contraction
hsa04261 Adrenergic signaling in cardiomyocytes
hsa05410 Hypertrophic cardiomyopathy (HCM)
hsa05414 Dilated cardiomyopathy (DCM)
Orthologous [Ortholog page] ACTA1 (hsa)ACTA2 (hsa)ACTB (hsa)ACTG1 (hsa)ACTG2 (hsa)ACTR1B (hsa)ACTR1A (hsa)ACTL7B (hsa)Acta1 (mmu)Actb (mmu)Actc1 (mmu)Actg1 (mmu)Actg2 (mmu)Actl7b (mmu)Acta2 (mmu)Actg2 (rno)Actc1 (rno)Acta1 (rno)Act5C (dme)Act42A (dme)Arp53D (dme)Act57B (dme)Act79B (dme)Arp1 (dme)Act88F (dme)Act87E (dme)Actr1a (mmu)actb1 (dre)actb2 (dre)actc1b (dre)Actrt2 (mmu)Actrt1 (mmu)Actrt3 (mmu)Acta2 (rno)Actb (rno)ACTRT3 (hsa)ACTRT1 (hsa)ACTRT2 (hsa)arp-1 (cel)act-5 (cel)act-3 (cel)act-2 (cel)act-1 (cel)act-4 (cel)Actr1b (mmu)Actbl2 (mmu)Actg1 (rno)Actl9b (rno)Actr1a (rno)Actbl2 (rno)Actrt2 (rno)Actrt1 (rno)Actl7b (rno)Actr1b (rno)acta2 (dre)si:ch73-187m15.4 (dre)ACTBL2 (hsa)Actrt3 (rno)ACTG2 (gga)ACTB (gga)ACTB (cfa)ACTR1A (cfa)actr1 (dre)acta1b (dre)actc1a (dre)actc1c (dre)ACTG1 (gga)ACTA1 (gga)ACTC1 (gga)ACTA2 (gga)ACTR1A (gga)ACTBL2L (gga)POTEE (hsa)ACTG2 (cfa)ACTG1 (cfa)ACTA2 (cfa)ACTC1 (cfa)ACTRT2 (cfa)ACTL7B (cfa)LOC483676 (cfa)ACTBL2 (cfa)ACTRT3 (cfa)ACTA1 (cfa)ACTRT1 (cfa)acta1a (dre)zgc:86709 (dre)ACTB (mcc)ACTR1B (cfa)POTEI (hsa)POTEJ (hsa)Potef (rno)ACTC1 (mcc)ACTRT3 (mcc)ACTRT1 (mcc)ACTR1B (mcc)ACTG2 (mcc)ACTBL2 (mcc)ACTL7B (mcc)ACTRT2 (mcc)ACTR1A (mcc)ACTG1 (mcc)LOC721299 (mcc)POTEF (hsa)ACTC2L (gga)ACT1 (sce)arp1 (spo)act1 (spo)alp5 (spo)LOC100361457 (rno)ACTA1 (mcc)ACTA2 (mcc)LOC100428865 (mcc)LOC102552318 (rno)LOC102636989 (mmu)ACT85CL (gga)
Subcellular
localization
cysk 10  (predict for NP_005150.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04270 Vascular smooth muscle contraction 4
hsa05414 Dilated cardiomyopathy (DCM) 3
hsa04022 cGMP-PKG signaling pathway 3
hsa04261 Adrenergic signaling in cardiomyocytes 3
hsa05410 Hypertrophic cardiomyopathy (HCM) 2
Genes directly connected with ACTC1 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
6.1 ACTG2 actin, gamma 2, smooth muscle, enteric [detail] 72
13.1 ACTA1 actin, alpha 1, skeletal muscle [detail] 58
238.7 CASQ2 calsequestrin 2 [detail] 845
546.3 FLNC filamin C [detail] 2318
1677.8 PRUNE2 prune homolog 2 [detail] 158471
Coexpressed
gene list
[Coexpressed gene list for ACTC1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 70    
Refseq ID (protein) NP_005150.1 


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