[][] rno Cdk1 Gene 
functional annotation
Function   cyclin-dependent kinase 1
GO BP
GO:1905448 [list] [network] positive regulation of mitochondrial ATP synthesis coupled electron transport  (2 genes)  IEA ISO  
GO:0051445 [list] [network] regulation of meiotic cell cycle  (3 genes)  IBA  
GO:0044772 [list] [network] mitotic cell cycle phase transition  (5 genes)  IBA ISO  
GO:0090166 [list] [network] Golgi disassembly  (6 genes)  IDA  
GO:0030261 [list] [network] chromosome condensation  (10 genes)  IMP  
GO:0055015 [list] [network] ventricular cardiac muscle cell development  (10 genes)  IEP  
GO:0016572 [list] [network] histone phosphorylation  (11 genes)  IEA  
GO:0034501 [list] [network] protein localization to kinetochore  (11 genes)  IEA ISO  
GO:0033160 [list] [network] positive regulation of protein import into nucleus, translocation  (18 genes)  IMP  
GO:0007095 [list] [network] mitotic G2 DNA damage checkpoint  (19 genes)  IEA ISO  
GO:0010971 [list] [network] positive regulation of G2/M transition of mitotic cell cycle  (20 genes)  IEA ISO  
GO:0014075 [list] [network] response to amine  (22 genes)  IEP  
GO:0060045 [list] [network] positive regulation of cardiac muscle cell proliferation  (26 genes)  IMP  
GO:1900182 [list] [network] positive regulation of protein localization to nucleus  (26 genes)  ISO  
GO:0046688 [list] [network] response to copper ion  (29 genes)  IEP  
GO:0045931 [list] [network] positive regulation of mitotic cell cycle  (35 genes)  IMP  
GO:0007569 [list] [network] cell aging  (39 genes)  IDA  
GO:0045740 [list] [network] positive regulation of DNA replication  (45 genes)  IMP  
GO:0046686 [list] [network] response to cadmium ion  (45 genes)  IEP  
GO:0048678 [list] [network] response to axon injury  (50 genes)  IEP  
GO:0018107 [list] [network] peptidyl-threonine phosphorylation  (68 genes)  ISO ISS  
GO:0010243 [list] [network] response to organonitrogen compound  (69 genes)  IDA  
GO:0006461 [list] [network] protein-containing complex assembly  (72 genes)  IDA  
GO:0030855 [list] [network] epithelial cell differentiation  (77 genes)  IEA ISO  
GO:0000226 [list] [network] microtubule cytoskeleton organization  (79 genes)  IBA  
GO:0042542 [list] [network] response to hydrogen peroxide  (80 genes)  IEP  
GO:0070301 [list] [network] cellular response to hydrogen peroxide  (84 genes)  IEP  
GO:0031100 [list] [network] animal organ regeneration  (90 genes)  IMP  
GO:0000278 [list] [network] mitotic cell cycle  (93 genes)  IEP  
GO:0014823 [list] [network] response to activity  (97 genes)  IEP  
GO:0009636 [list] [network] response to toxic substance  (123 genes)  IEP  
GO:0018105 [list] [network] peptidyl-serine phosphorylation  (150 genes)  IDA ISO ISS  
GO:0006281 [list] [network] DNA repair  (168 genes)  IBA  
GO:0051301 [list] [network] cell division  (180 genes)  IEA  
GO:0045471 [list] [network] response to ethanol  (197 genes)  IDA  
GO:0008283 [list] [network] cell proliferation  (232 genes)  IEA ISO  
GO:0014070 [list] [network] response to organic cyclic compound  (271 genes)  IEP  
GO:0006915 [list] [network] apoptotic process  (364 genes)  IEA  
GO:0010628 [list] [network] positive regulation of gene expression  (431 genes)  IMP  
GO:0006468 [list] [network] protein phosphorylation  (485 genes)  ISO  
GO:0042493 [list] [network] response to drug  (523 genes)  IEP  
GO:0043066 [list] [network] negative regulation of apoptotic process  (531 genes)  IEA ISO  
GO CC
GO:0097125 [list] [network] cyclin B1-CDK1 complex  (2 genes)  IEA ISO  
GO:0000307 [list] [network] cyclin-dependent protein kinase holoenzyme complex  (24 genes)  ISO  
GO:0005876 [list] [network] spindle microtubule  (33 genes)  IEA ISO  
GO:0072686 [list] [network] mitotic spindle  (52 genes)  IBA ISO ISS  
GO:0000784 [list] [network] nuclear chromosome, telomeric region  (114 genes)  IEA ISO  
GO:0030496 [list] [network] midbody  (140 genes)  IEA ISO  
GO:0005759 [list] [network] mitochondrial matrix  (168 genes)  IEA ISO  
GO:0005813 [list] [network] centrosome  (456 genes)  ISO ISS  
GO:0016020 [list] [network] membrane  (2183 genes)  IEA ISO  
GO:0070062 [list] [network] extracellular exosome  (2641 genes)  IEA ISO  
GO:0005829 [list] [network] cytosol  (3046 genes)  IEA ISO  
GO:0005737 [list] [network] cytoplasm  (4459 genes)  IDA  
GO:0005634 [list] [network] nucleus  (4802 genes)  IDA ISO  
GO MF
GO:0035173 [list] [network] histone kinase activity  (4 genes)  IDA ISO  
GO:0097472 [list] [network] cyclin-dependent protein kinase activity  (4 genes)  ISO  
GO:0008353 [list] [network] RNA polymerase II carboxy-terminal domain kinase activity  (16 genes)  IEA ISO  
GO:0004693 [list] [network] cyclin-dependent protein serine/threonine kinase activity  (26 genes)  IDA ISO  
GO:0030332 [list] [network] cyclin binding  (30 genes)  IPI ISO  
GO:0030544 [list] [network] Hsp70 protein binding  (42 genes)  IEA ISO  
GO:0016301 [list] [network] kinase activity  (122 genes)  ISO  
GO:0004672 [list] [network] protein kinase activity  (271 genes)  ISO  
GO:0004674 [list] [network] protein serine/threonine kinase activity  (313 genes)  ISO ISS  
GO:0003682 [list] [network] chromatin binding  (462 genes)  IEA ISO  
GO:0005524 [list] [network] ATP binding  (1374 genes)  IEA  
GO:0005515 [list] [network] protein binding  (1646 genes)  IPI  
KEGG rno04110 Cell cycle
rno04114 Oocyte meiosis
rno04115 p53 signaling pathway
rno04218 Cellular senescence
rno04540 Gap junction
rno04914 Progesterone-mediated oocyte maturation
rno05168 Herpes simplex infection
rno05169 Epstein-Barr virus infection
rno05203 Viral carcinogenesis
Orthologous [Ortholog page] CDK1 (hsa)CDK2 (hsa)CDK3 (hsa)CDK5 (hsa)Cdk1 (mmu)Cdk2 (mmu)Cdk5 (mmu)Cdk1 (dme)Cdk5 (dme)Cdk2 (dme)cdk5 (dre)cdk1 (dre)Cdk5 (rno)cdk-2 (cel)cdk-1 (cel)cdk-5 (cel)Cdk2 (rno)CDK1 (gga)cdk2 (dre)CDK3 (gga)CDK5 (cfa)CDK3 (cfa)CDK1 (mcc)CDK3 (mcc)CDK2 (mcc)CDK5 (mcc)CDC28 (sce)PHO85 (sce)pef1 (spo)cdc2 (spo)CDK5 (gga)CDK2 (gga)CDK2 (cfa)CDK1 (cfa)CDK3 (gga)
Subcellular
localization
cyto 7,  cyto_nucl 5,  cyto_pero 4,  nucl 1  (predict for NP_062169.1)
cyto 7,  cyto_nucl 5,  cyto_pero 4,  nucl 1  (predict for XP_006256415.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04110 Cell cycle 3
rno04115 p53 signaling pathway 3
rno00240 Pyrimidine metabolism 2
rno00983 Drug metabolism - other enzymes 2
rno04540 Gap junction 2
Genes directly connected with Cdk1 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
6.1 Rrm2 ribonucleotide reductase regulatory subunit M2 [detail] 362720
6.6 Kif20a kinesin family member 20A [detail] 361308
8.4 Ube2c ubiquitin-conjugating enzyme E2C [detail] 296368
9.0 Ect2 epithelial cell transforming 2 [detail] 361921
9.1 Cdca3 cell division cycle associated 3 [detail] 297594
18.3 Spc25 SPC25, NDC80 kinetochore complex component [detail] 295661
29.4 Pclaf PCNA clamp associated factor [detail] 300795
30.0 Aurkb aurora kinase B [detail] 114592
60.2 Ckap2 cytoskeleton associated protein 2 [detail] 306575
130.9 Spc24 SPC24, NDC80 kinetochore complex component [detail] 363028
349.0 Stmn1 stathmin 1 [detail] 29332
Coexpressed
gene list
[Coexpressed gene list for Cdk1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 54237    
Refseq ID (protein) NP_062169.1 
XP_006256415.1 


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