[][] gga SYK Gene 
functional annotation
Function   spleen associated tyrosine kinase
GO BP
GO:0002366 [list] [network] leukocyte activation involved in immune response  (1 genes)  ISS  
GO:0002554 [list] [network] serotonin secretion by platelet  (1 genes)  ISS  
GO:0007159 [list] [network] leukocyte cell-cell adhesion  (1 genes)  ISS  
GO:0010543 [list] [network] regulation of platelet activation  (1 genes)  ISS  
GO:0032928 [list] [network] regulation of superoxide anion generation  (1 genes)  ISS  
GO:0043313 [list] [network] regulation of neutrophil degranulation  (1 genes)  ISS  
GO:0045579 [list] [network] positive regulation of B cell differentiation  (1 genes)  IBA  
GO:0071226 [list] [network] cellular response to molecule of fungal origin  (1 genes)  ISS  
GO:0090237 [list] [network] regulation of arachidonic acid secretion  (1 genes)  ISS  
GO:0090330 [list] [network] regulation of platelet aggregation  (1 genes)  IBA ISS  
GO:0001945 [list] [network] lymph vessel development  (2 genes)  ISS  
GO:0002283 [list] [network] neutrophil activation involved in immune response  (2 genes)  IBA ISS  
GO:0033630 [list] [network] positive regulation of cell adhesion mediated by integrin  (2 genes)  IBA ISS  
GO:0045780 [list] [network] positive regulation of bone resorption  (2 genes)  ISS  
GO:0046641 [list] [network] positive regulation of alpha-beta T cell proliferation  (2 genes)  IBA  
GO:0050764 [list] [network] regulation of phagocytosis  (2 genes)  ISS  
GO:0002281 [list] [network] macrophage activation involved in immune response  (3 genes)  IBA ISS  
GO:0043306 [list] [network] positive regulation of mast cell degranulation  (3 genes)  IBA  
GO:0048514 [list] [network] blood vessel morphogenesis  (3 genes)  ISS  
GO:0050853 [list] [network] B cell receptor signaling pathway  (3 genes)  IMP  
GO:0030593 [list] [network] neutrophil chemotaxis  (4 genes)  ISS  
GO:0070301 [list] [network] cellular response to hydrogen peroxide  (4 genes)  IMP  
GO:0070372 [list] [network] regulation of ERK1 and ERK2 cascade  (5 genes)  ISS  
GO:0002250 [list] [network] adaptive immune response  (11 genes)  IMP  
GO:0007229 [list] [network] integrin-mediated signaling pathway  (11 genes)  ISS  
GO:0038083 [list] [network] peptidyl-tyrosine autophosphorylation  (11 genes)  IBA  
GO:0007169 [list] [network] transmembrane receptor protein tyrosine kinase signaling pathway  (15 genes)  IBA  
GO:0042742 [list] [network] defense response to bacterium  (21 genes)  ISS  
GO:0016477 [list] [network] cell migration  (25 genes)  IBA  
GO:0035556 [list] [network] intracellular signal transduction  (25 genes)  IEA  
GO:0006468 [list] [network] protein phosphorylation  (29 genes)  IMP  
GO:0006954 [list] [network] inflammatory response  (30 genes)  IBA  
GO:0018108 [list] [network] peptidyl-tyrosine phosphorylation  (30 genes)  IMP  
GO:0045087 [list] [network] innate immune response  (38 genes)  IBA ISS  
GO:0030154 [list] [network] cell differentiation  (95 genes)  IBA  
GO CC
GO:0032009 [list] [network] early phagosome  (1 genes)  ISS  
GO:0031234 [list] [network] extrinsic component of cytoplasmic side of plasma membrane  (16 genes)  IBA  
GO:0005829 [list] [network] cytosol  (236 genes)  IEA  
GO MF
GO:0004715 [list] [network] non-membrane spanning protein tyrosine kinase activity  (12 genes)  IMP  
GO:0004713 [list] [network] protein tyrosine kinase activity  (14 genes)  IMP  
GO:0005102 [list] [network] signaling receptor binding  (25 genes)  IBA  
GO:0005524 [list] [network] ATP binding  (211 genes)  IEA  
KEGG
Orthologous [Ortholog page] SYK (hsa)ZAP70 (hsa)Syk (mmu)Zap70 (mmu)Syk (rno)Shark (dme)ZK622.1 (cel)Zap70 (rno)syk (dre)ZAP70 (gga)SYK (cfa)zap70 (dre)SYK (mcc)LOC707555 (mcc)ZAP70 (cfa)LOC100910488 (rno)
Subcellular
localization
cyto 8,  mito 1,  pero 1,  mito_pero 1  (predict for NP_001026601.1)
cyto 9,  mito 1  (predict for XP_015135783.1)
cyto 9,  mito 1  (predict for XP_015135784.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04020 Calcium signaling pathway 2
gga04672 Intestinal immune network for IgA production 2
Genes directly connected with SYK on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
330.7 TNFSF13B tumor necrosis factor superfamily member 13b [detail] 374229
412.2 POU2AF1 POU class 2 associating factor 1 [detail] 373994
560.8 TLR7 toll like receptor 7 [detail] 418638
612.5 BLNK B-cell linker [detail] 395733
621.5 PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 [detail] 419210
871.7 SWAP70 SWAP switching B-cell complex 70kDa subunit [detail] 423044
1032.8 RUBCNL RUN and cysteine rich domain containing beclin 1 interacting protein like [detail] 418854
1373.3 BCL6 B-cell CLL/lymphoma 6 [detail] 424912
Coexpressed
gene list
[Coexpressed gene list for SYK]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 427272    
Refseq ID (protein) NP_001026601.1 
XP_015135783.1 
XP_015135784.1 


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