[][] gga HMGCS1 Gene 
functional annotation
Function   3-hydroxy-3-methylglutaryl-CoA synthase 1
GO BP
GO:0008299 [list] [network] isoprenoid biosynthetic process  (1 genes)  IEA  
GO:0006695 [list] [network] cholesterol biosynthetic process  (4 genes)  IEA  
GO CC
GO:0005737 [list] [network] cytoplasm  (486 genes)  IEA  
GO MF
GO:0004421 [list] [network] hydroxymethylglutaryl-CoA synthase activity  (1 genes)  IEA  
KEGG gga00072 Synthesis and degradation of ketone bodies
gga00280 Valine, leucine and isoleucine degradation
gga00650 Butanoate metabolism
gga00900 Terpenoid backbone biosynthesis
Orthologous [Ortholog page] HMGCS1 (hsa)HMGCS2 (hsa)Hmgcs2 (mmu)Hmgcs2 (rno)Hmgcs1 (rno)Hmgs (dme)hmgs-1 (cel)Hmgcs1 (mmu)hmgcs1 (dre)HMGCS2 (gga)HMGCS1 (cfa)HMGCS2 (cfa)HMGCS1 (mcc)HMGCS2 (mcc)ERG13 (sce)hcs1 (spo)LOC107049309 (gga)
Subcellular
localization
cyto 5,  cyto_nucl 5,  nucl 2,  mito 2  (predict for NP_990742.1)
nucl 7,  cyto_nucl 5,  cyto 2  (predict for XP_015132738.1)
nucl 7,  cyto_nucl 5,  cyto 2  (predict for XP_015132739.1)
nucl 7,  cyto_nucl 5,  cyto 2  (predict for XP_015132740.1)
cyto 5,  cyto_nucl 4,  nucl 2,  mito 2  (predict for XP_015132741.1)
cyto 5,  cyto_nucl 4,  nucl 2,  mito 2  (predict for XP_015132742.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga00100 Steroid biosynthesis 7
gga00900 Terpenoid backbone biosynthesis 5
gga01212 Fatty acid metabolism 4
gga00280 Valine, leucine and isoleucine degradation 3
gga00650 Butanoate metabolism 3
Genes directly connected with HMGCS1 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
13.0 IDI1 isopentenyl-diphosphate delta isomerase 1 [detail] 420459
20.4 MSMO1 methylsterol monooxygenase 1 [detail] 422423
44.7 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase [detail] 395145
312.7 ACAT2 acetyl-CoA acetyltransferase 2 [detail] 421587
366.4 LOC427192 similar to hypothetical protein MGC42105 [detail] 427192
1201.0 SLC20A2 solute carrier family 20 member 2 [detail] 422493
Coexpressed
gene list
[Coexpressed gene list for HMGCS1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 396379    
Refseq ID (protein) NP_990742.1 
XP_015132738.1 
XP_015132739.1 
XP_015132740.1 
XP_015132741.1 
XP_015132742.1 


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