[][] gga TOP2B Gene 
functional annotation
Function   DNA topoisomerase 2-beta
GO BP
GO:0000819 [list] [network] sister chromatid segregation  (2 genes)  IBA  
GO:0006265 [list] [network] DNA topological change  (2 genes)  ISS  
GO:0044774 [list] [network] mitotic DNA integrity checkpoint  (2 genes)  IBA  
GO:0000712 [list] [network] resolution of meiotic recombination intermediates  (4 genes)  IBA  
GO CC
GO:0000792 [list] [network] heterochromatin  (3 genes)  IDA  
GO:0030529 [list] [network] ribonucleoprotein complex  (10 genes)  ISS  
GO:0005654 [list] [network] nucleoplasm  (117 genes)  IEA  
GO:0005634 [list] [network] nucleus  (588 genes)  IDA  
GO MF
GO:0003916 [list] [network] DNA topoisomerase activity  (1 genes)  ISS  
GO:0043021 [list] [network] ribonucleoprotein complex binding  (1 genes)  ISS  
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (2 genes)  ISS  
GO:0003677 [list] [network] DNA binding  (163 genes)  IEA  
GO:0005524 [list] [network] ATP binding  (211 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (241 genes)  IEA  
KEGG
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2b (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)TOP2 (sce)top2 (spo)
Subcellular
localization
cyto_nucl 5,  cyto 4,  nucl 4  (predict for NP_990413.1)
nucl 5,  cyto_nucl 4,  cyto 4  (predict for XP_015136786.1)
nucl 5,  cyto_nucl 4,  cyto 4  (predict for XP_015136787.1)
nucl 5,  cyto_nucl 4,  cyto 4  (predict for XP_015136788.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04120 Ubiquitin mediated proteolysis 2
Genes directly connected with TOP2B on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
376.7 UBR5 ubiquitin protein ligase E3 component n-recognin 5 [detail] 420252
423.7 ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1 [detail] 420170
704.0 STAU1 staufen double-stranded RNA binding protein 1 [detail] 419213
1189.8 RHOBTB1 Rho related BTB domain containing 1 [detail] 423664
Coexpressed
gene list
[Coexpressed gene list for TOP2B]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 395966    
Refseq ID (protein) NP_990413.1 
XP_015136786.1 
XP_015136787.1 
XP_015136788.1 


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