[][] rno Top2b Gene 
functional annotation
Function   DNA topoisomerase II beta
GO BP
GO:2001034 [list] [network] positive regulation of double-strand break repair via nonhomologous end joining  (6 genes)  IMP  
GO:0006265 [list] [network] DNA topological change  (10 genes)  ISO  
GO:0071318 [list] [network] cellular response to ATP  (15 genes)  IDA  
GO:0007569 [list] [network] cell aging  (39 genes)  IDA  
GO:0070301 [list] [network] cellular response to hydrogen peroxide  (84 genes)  IDA  
GO:0030900 [list] [network] forebrain development  (95 genes)  ISO  
GO:0007409 [list] [network] axonogenesis  (117 genes)  ISO  
GO:0001764 [list] [network] neuron migration  (126 genes)  ISO  
GO CC
GO:0000792 [list] [network] heterochromatin  (36 genes)  ISO  
GO:0005694 [list] [network] chromosome  (83 genes)  ISO  
GO:0005730 [list] [network] nucleolus  (813 genes)  IDA ISO  
GO:0005654 [list] [network] nucleoplasm  (1897 genes)  ISO  
GO:0005829 [list] [network] cytosol  (3046 genes)  ISO  
GO:0005634 [list] [network] nucleus  (4802 genes)  IDA ISO  
GO MF
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (3 genes)  ISO  
GO:0043021 [list] [network] ribonucleoprotein complex binding  (40 genes)  IPI  
GO:0005080 [list] [network] protein kinase C binding  (54 genes)  ISO  
GO:0042826 [list] [network] histone deacetylase binding  (118 genes)  ISO  
GO:0008022 [list] [network] protein C-terminus binding  (225 genes)  ISO  
GO:0019899 [list] [network] enzyme binding  (410 genes)  ISO  
GO:0003682 [list] [network] chromatin binding  (462 genes)  ISO  
GO:0046982 [list] [network] protein heterodimerization activity  (593 genes)  ISO  
KEGG rno01524 Platinum drug resistance
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2b (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)TOP2 (sce)top2 (spo)
Subcellular
localization
cyto_nucl 5,  nucl 5,  cyto 4  (predict for NP_001094328.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05166 HTLV-I infection 3
rno04114 Oocyte meiosis 2
rno04530 Tight junction 2
rno04914 Progesterone-mediated oocyte maturation 2
rno05165 Human papillomavirus infection 2
Genes directly connected with Top2b on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
218.1 Stag2 stromal antigen 2 [detail] 313304
497.1 Zfp638 zinc finger protein 638 [detail] 312491
568.1 Pds5b PDS5 cohesin associated factor B [detail] 304218
1356.1 Kdelc2 KDEL motif containing 2 [detail] 315664
Coexpressed
gene list
[Coexpressed gene list for Top2b]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 361100    
Refseq ID (protein) NP_001094328.1 


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