[][] dme Top2 Gene 
functional annotation
Function   Topoisomerase 2
GO BP
GO:0044774 [list] [network] mitotic DNA integrity checkpoint  (1 genes)  IBA  
GO:0051310 [list] [network] metaphase plate congression  (3 genes)  IDA  
GO:0000819 [list] [network] sister chromatid segregation  (4 genes)  IBA IDA  
GO:0006265 [list] [network] DNA topological change  (7 genes)  IDA  
GO:0000712 [list] [network] resolution of meiotic recombination intermediates  (9 genes)  IBA  
GO:0007060 [list] [network] male meiosis chromosome segregation  (19 genes)  IMP  
GO:0007076 [list] [network] mitotic chromosome condensation  (22 genes)  IMP  
GO:0051321 [list] [network] meiotic cell cycle  (24 genes)  TAS  
GO:0000070 [list] [network] mitotic sister chromatid segregation  (28 genes)  IMP  
GO:0030261 [list] [network] chromosome condensation  (32 genes)  IMP  
GO:0007095 [list] [network] mitotic G2 DNA damage checkpoint  (72 genes)  IGI  
GO:0006342 [list] [network] chromatin silencing  (97 genes)  IDA  
GO:0000278 [list] [network] mitotic cell cycle  (132 genes)  IMP TAS  
GO CC
GO:0008623 [list] [network] CHRAC  (5 genes)  IDA  
GO:0016590 [list] [network] ACF complex  (6 genes)  IDA  
GO:0000793 [list] [network] condensed chromosome  (14 genes)  IDA  
GO:0005694 [list] [network] chromosome  (26 genes)  IDA  
GO:0005634 [list] [network] nucleus  (1529 genes)  IBA IDA  
GO MF
GO:0000182 [list] [network] rDNA binding  (2 genes)  IDA  
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (2 genes)  IDA  
GO:0003696 [list] [network] satellite DNA binding  (4 genes)  IDA  
GO:0000400 [list] [network] four-way junction DNA binding  (9 genes)  IDA  
GO:0003682 [list] [network] chromatin binding  (126 genes)  IDA  
GO:0003729 [list] [network] mRNA binding  (173 genes)  IDA  
GO:0003677 [list] [network] DNA binding  (393 genes)  IDA  
GO:0005515 [list] [network] protein binding  (546 genes)  IPI  
GO:0005524 [list] [network] ATP binding  (611 genes)  IEA  
KEGG
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2b (mmu)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)TOP2 (sce)top2 (spo)
Subcellular
localization
nucl 6,  cyto_nucl 5,  cyto 4,  cyto_mito 2  (predict for NP_001260580.1)
nucl 6,  cyto_nucl 5,  cyto 4,  cyto_mito 2  (predict for NP_476760.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme03013 RNA transport 5
dme03040 Spliceosome 4
Genes directly connected with Top2 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
113.1 Mtor Megator [detail] 36264
135.0 SMC2 Structural maintenance of chromosomes 2 [detail] 36653
197.9 Prp8 pre-mRNA processing factor 8 [detail] 36304
289.9 Nup154 Nucleoporin 154kD [detail] 34527
405.2 kuk kugelkern [detail] 42063
408.6 Cpsf160 Cleavage and polyadenylation specificity factor 160 [detail] 44250
Coexpressed
gene list
[Coexpressed gene list for Top2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 35225    
Refseq ID (protein) NP_001260580.1 
NP_476760.1 


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