[][] dre top2a Gene 
functional annotation
Function   DNA topoisomerase II alpha
GO BP
GO:0000819 [list] [network] sister chromatid segregation  (2 genes)  IBA  
GO:0031100 [list] [network] animal organ regeneration  (2 genes)  IMP  
GO:0044774 [list] [network] mitotic DNA integrity checkpoint  (2 genes)  IBA  
GO:0030261 [list] [network] chromosome condensation  (5 genes)  ISS  
GO:0000712 [list] [network] resolution of meiotic recombination intermediates  (9 genes)  IBA  
GO:0006259 [list] [network] DNA metabolic process  (10 genes)  IEA  
GO:0006265 [list] [network] DNA topological change  (11 genes)  IEA ISS  
GO:0007059 [list] [network] chromosome segregation  (30 genes)  IMP ISS  
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II  (155 genes)  ISS  
GO CC
GO:0009330 [list] [network] DNA topoisomerase complex (ATP-hydrolyzing)  (2 genes)  ISS  
GO:0005634 [list] [network] nucleus  (2896 genes)  IBA ISS  
GO MF
GO:0003916 [list] [network] DNA topoisomerase activity  (4 genes)  IEA  
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (4 genes)  IEA ISS  
GO:0008094 [list] [network] DNA-dependent ATPase activity  (20 genes)  ISS  
GO:0016853 [list] [network] isomerase activity  (86 genes)  IEA  
GO:0003677 [list] [network] DNA binding  (1382 genes)  IEA  
GO:0000166 [list] [network] nucleotide binding  (1485 genes)  IEA  
GO:0005524 [list] [network] ATP binding  (1624 genes)  IEA  
KEGG
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2b (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)TOP2 (sce)top2 (spo)
Subcellular
localization
nucl 7,  cyto_nucl 5,  cyto 2  (predict for NP_001296944.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre03030 DNA replication 2
dre04110 Cell cycle 2
Genes directly connected with top2a on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
75.2 mki67 marker of proliferation Ki-67 [detail] 564521
204.2 mcm6 minichromosome maintenance complex component 6 [detail] 566409
288.1 mastl microtubule associated serine/threonine kinase-like [detail] 445215
419.5 melk maternal embryonic leucine zipper kinase [detail] 30724
589.3 tdp1 tyrosyl-DNA phosphodiesterase 1 [detail] 571485
593.4 ckap5 cytoskeleton associated protein 5 [detail] 492614
Coexpressed
gene list
[Coexpressed gene list for top2a]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 323733    
Refseq ID (protein) NP_001296944.1 


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