[][] hsa LDLRAP1 Gene 
functional annotation
Function   low density lipoprotein receptor adaptor protein 1
GO BP
GO:0090205 [list] [network] positive regulation of cholesterol metabolic process  (1 genes)  IC  
GO:1905602 [list] [network] positive regulation of receptor-mediated endocytosis involved in cholesterol transport  (2 genes)  IMP  
GO:0090118 [list] [network] receptor-mediated endocytosis involved in cholesterol transport  (3 genes)  IMP  
GO:0042982 [list] [network] amyloid precursor protein metabolic process  (11 genes)  IMP  
GO:1903076 [list] [network] regulation of protein localization to plasma membrane  (14 genes)  IMP  
GO:0030301 [list] [network] cholesterol transport  (19 genes)  NAS  
GO:0043393 [list] [network] regulation of protein binding  (19 genes)  IMP  
GO:0048260 [list] [network] positive regulation of receptor-mediated endocytosis  (19 genes)  IMP  
GO:0034383 [list] [network] low-density lipoprotein particle clearance  (24 genes)  IMP  
GO:0031623 [list] [network] receptor internalization  (38 genes)  IMP  
GO:0009967 [list] [network] positive regulation of signal transduction  (59 genes)  IEA  
GO:0008203 [list] [network] cholesterol metabolic process  (63 genes)  NAS  
GO:0042632 [list] [network] cholesterol homeostasis  (66 genes)  IMP  
GO:0061024 [list] [network] membrane organization  (130 genes)  TAS  
GO:0006898 [list] [network] receptor-mediated endocytosis  (194 genes)  IDA  
GO CC
GO:0030121 [list] [network] AP-1 adaptor complex  (6 genes)  IDA  
GO:0005883 [list] [network] neurofilament  (8 genes)  ISS  
GO:0030122 [list] [network] AP-2 adaptor complex  (13 genes)  IDA  
GO:0009925 [list] [network] basal plasma membrane  (30 genes)  IDA  
GO:0030665 [list] [network] clathrin-coated vesicle membrane  (42 genes)  TAS  
GO:0009898 [list] [network] cytoplasmic side of plasma membrane  (44 genes)  IDA  
GO:0055037 [list] [network] recycling endosome  (110 genes)  IDA  
GO:0005769 [list] [network] early endosome  (234 genes)  IDA  
GO:0030424 [list] [network] axon  (253 genes)  ISS  
GO:0005886 [list] [network] plasma membrane  (4337 genes)  TAS  
GO:0005829 [list] [network] cytosol  (4875 genes)  IDA  
GO MF
GO:0035591 [list] [network] signaling adaptor activity  (8 genes)  IDA  
GO:0035612 [list] [network] AP-2 adaptor complex binding  (10 genes)  IDA  
GO:0035615 [list] [network] clathrin adaptor activity  (11 genes)  IDA  
GO:0030159 [list] [network] receptor signaling complex scaffold activity  (20 genes)  IMP  
GO:0050750 [list] [network] low-density lipoprotein particle receptor binding  (21 genes)  IPI  
GO:0001784 [list] [network] phosphotyrosine residue binding  (35 genes)  IDA  
GO:0030276 [list] [network] clathrin binding  (52 genes)  IDA  
GO:0001540 [list] [network] amyloid-beta binding  (60 genes)  IPI  
GO:0005546 [list] [network] phosphatidylinositol-4,5-bisphosphate binding  (63 genes)  IDA  
GO:0005515 [list] [network] protein binding  (9334 genes)  IPI  
KEGG hsa04144 Endocytosis
hsa04979 Cholesterol metabolism
Orthologous [Ortholog page] Ldlrap1 (mmu)LDLRAP1 (gga)Ldlrap1 (rno)LDLRAP1 (cfa)LDLRAP1 (mcc)ldlrap1b (dre)
Subcellular
localization
cyto 3,  mito 3,  cyto_nucl 3,  nucl 3  (predict for NP_056442.2)
mito 3,  mito_nucl 3,  cyto 3,  nucl 2,  extr 1,  golg 1  (predict for XP_006710622.1)
mito 3,  mito_nucl 3,  cyto 3,  nucl 3,  extr 1,  golg 1  (predict for XP_006710623.1)
mito 4,  mito_nucl 3,  cyto 3,  nucl 2  (predict for XP_006710624.1)
cyto 3,  mito 3,  cyto_nucl 3,  nucl 3  (predict for XP_011539511.1)
mito 3,  mito_nucl 3,  cyto 3,  nucl 2,  extr 1,  golg 1  (predict for XP_011539512.1)
mito 3,  mito_nucl 3,  cyto 3,  nucl 3,  extr 1,  golg 1  (predict for XP_011539513.1)
mito 4,  mito_nucl 3,  cyto 3,  nucl 2,  cyto_golg 2  (predict for XP_011539514.1)
cyto 6,  nucl 3,  cyto_pero 3,  cyto_plas 3,  cyto_golg 3  (predict for XP_016856483.1)
cyto 4,  cyto_nucl 3,  mito_nucl 2,  nucl 2,  mito 1,  golg 1,  plas 1,  extr 1,  extr_plas 1  (predict for XP_016856484.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00590 Arachidonic acid metabolism 2
hsa04144 Endocytosis 2
hsa04666 Fc gamma R-mediated phagocytosis 2
Genes directly connected with LDLRAP1 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
400.7 MAN1C1 mannosidase alpha class 1C member 1 [detail] 57134
927.2 TCEA3 transcription elongation factor A3 [detail] 6920
1172.0 DENND2D DENN domain containing 2D [detail] 79961
1190.8 RCAN3 RCAN family member 3 [detail] 11123
1378.2 VIPR1 vasoactive intestinal peptide receptor 1 [detail] 7433
1572.3 DHRS3 dehydrogenase/reductase 3 [detail] 9249
Coexpressed
gene list
[Coexpressed gene list for LDLRAP1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 26119    
Refseq ID (protein) NP_056442.2 
XP_006710622.1 
XP_006710623.1 
XP_006710624.1 
XP_011539511.1 
XP_011539512.1 
XP_011539513.1 
XP_011539514.1 
XP_016856483.1 
XP_016856484.1 


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