[][] spo top2 Gene 
functional annotation
Function   DNA topoisomerase II
GO BP
GO:0051306 [list] [network] mitotic sister chromatid separation  (3 genes)  IMP  
GO:0006265 [list] [network] DNA topological change  (4 genes)  IGI IMP  
GO:0000712 [list] [network] resolution of meiotic recombination intermediates  (6 genes)  IGI  
GO:0007076 [list] [network] mitotic chromosome condensation  (11 genes)  IMP  
GO:0006325 [list] [network] chromatin organization  (15 genes)  IGI  
GO:0000070 [list] [network] mitotic sister chromatid segregation  (53 genes)  IMP  
GO CC
GO:0035327 [list] [network] transcriptionally active chromatin  (3 genes)  IDA  
GO:0034506 [list] [network] chromosome, centromeric core domain  (13 genes)  IDA  
GO:0000790 [list] [network] nuclear chromatin  (266 genes)  IDA  
GO:0005634 [list] [network] nucleus  (2366 genes)  HDA IDA  
GO MF
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (1 genes)  IDA IGI IMP  
GO:0061505 [list] [network] DNA topoisomerase II activity  (1 genes)  IDA  
GO:0140082 [list] [network] SUMO-ubiquitin ligase activity  (3 genes)  IDA  
GO:0003677 [list] [network] DNA binding  (129 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (423 genes)  IEA  
GO:0005524 [list] [network] ATP binding  (550 genes)  IC  
GO:0005515 [list] [network] protein binding  (766 genes)  IPI  
KEGG
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2b (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)TOP2 (sce)
Subcellular
localization
nucl 8  (predict for NP_595805.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
spo04144 Endocytosis 2
spo04136 Autophagy - other 2
spo04138 Autophagy - yeast 2
Genes directly connected with top2 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
423.6 mip1 WD repeat-containing protein [detail] 2542404
464.6 stt4 1-phosphatidylinositol 4-kinase Stt4 (predicted) [detail] 2540883
467.3 sequence orphan [detail] 2543076
505.2 hrp1 ATP-dependent DNA helicase Hrp1 [detail] 2542363
554.2 rdp1 RNA-directed RNA polymerase Rdp1 [detail] 2542198
588.6 hrp3 ATP-dependent DNA helicase Hrp3 [detail] 2543064
605.4 sec72 Sec7 domain protein, ARF GEF Sec72 [detail] 2542107
Coexpressed
gene list
[Coexpressed gene list for top2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 2540541    
Refseq ID (protein) NP_595805.1 


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