[][] rno Sod1 Gene 
functional annotation
Function   superoxide dismutase 1
GO BP
GO:0097332 [list] [network] response to antipsychotic drug  (3 genes)  IEP  
GO:1902177 [list] [network] positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway  (4 genes)  IEA ISO  
GO:0045541 [list] [network] negative regulation of cholesterol biosynthetic process  (5 genes)  ISO ISS  
GO:0000303 [list] [network] response to superoxide  (6 genes)  ISO ISS  
GO:0034465 [list] [network] response to carbon monoxide  (6 genes)  IEP  
GO:0006309 [list] [network] apoptotic DNA fragmentation  (8 genes)  ISS  
GO:0032287 [list] [network] peripheral nervous system myelin maintenance  (8 genes)  ISO ISS  
GO:0060087 [list] [network] relaxation of vascular smooth muscle  (8 genes)  ISO ISS  
GO:0050665 [list] [network] hydrogen peroxide biosynthetic process  (9 genes)  IDA IMP ISO ISS  
GO:0060052 [list] [network] neurofilament cytoskeleton organization  (10 genes)  ISO ISS  
GO:0002262 [list] [network] myeloid cell homeostasis  (11 genes)  ISO ISS  
GO:0008090 [list] [network] retrograde axonal transport  (11 genes)  IEA ISO  
GO:0042554 [list] [network] superoxide anion generation  (11 genes)  IEA ISO  
GO:0019430 [list] [network] removal of superoxide radicals  (13 genes)  IDA IMP ISO ISS TAS  
GO:0035865 [list] [network] cellular response to potassium ion  (13 genes)  IEP  
GO:0071318 [list] [network] cellular response to ATP  (15 genes)  IEP  
GO:0060047 [list] [network] heart contraction  (16 genes)  ISO ISS  
GO:0032930 [list] [network] positive regulation of superoxide anion generation  (17 genes)  IEA ISO  
GO:0060088 [list] [network] auditory receptor cell stereocilium organization  (17 genes)  ISO ISS  
GO:0006801 [list] [network] superoxide metabolic process  (18 genes)  IDA ISO ISS TAS  
GO:0046716 [list] [network] muscle cell cellular homeostasis  (19 genes)  ISO ISS  
GO:0000302 [list] [network] response to reactive oxygen species  (20 genes)  ISO  
GO:0019226 [list] [network] transmission of nerve impulse  (22 genes)  ISO ISS  
GO:0008089 [list] [network] anterograde axonal transport  (26 genes)  IEA ISO  
GO:0046688 [list] [network] response to copper ion  (29 genes)  IEP IMP  
GO:0071276 [list] [network] cellular response to cadmium ion  (30 genes)  IEP  
GO:0051881 [list] [network] regulation of mitochondrial membrane potential  (31 genes)  ISO ISS  
GO:0001819 [list] [network] positive regulation of cytokine production  (32 genes)  ISO ISS  
GO:0045859 [list] [network] regulation of protein kinase activity  (33 genes)  ISO ISS  
GO:0040014 [list] [network] regulation of multicellular organism growth  (34 genes)  ISO ISS  
GO:0001895 [list] [network] retina homeostasis  (35 genes)  ISO ISS  
GO:0072593 [list] [network] reactive oxygen species metabolic process  (38 genes)  ISO ISS  
GO:0007569 [list] [network] cell aging  (39 genes)  ISO ISS  
GO:0006879 [list] [network] cellular iron ion homeostasis  (44 genes)  ISO ISS  
GO:0001975 [list] [network] response to amphetamine  (45 genes)  IEP  
GO:0046677 [list] [network] response to antibiotic  (47 genes)  IEP  
GO:0048678 [list] [network] response to axon injury  (50 genes)  ISO ISS  
GO:0006749 [list] [network] glutathione metabolic process  (52 genes)  ISO ISS  
GO:0007566 [list] [network] embryo implantation  (54 genes)  ISO ISS  
GO:0001541 [list] [network] ovarian follicle development  (60 genes)  ISO ISS  
GO:0008217 [list] [network] regulation of blood pressure  (61 genes)  ISO ISS  
GO:0006302 [list] [network] double-strand break repair  (62 genes)  ISS  
GO:0043087 [list] [network] regulation of GTPase activity  (65 genes)  IEA ISO  
GO:0043085 [list] [network] positive regulation of catalytic activity  (70 genes)  IDA ISO ISS  
GO:0034599 [list] [network] cellular response to oxidative stress  (77 genes)  IEP  
GO:0009408 [list] [network] response to heat  (78 genes)  ISO ISS  
GO:0042542 [list] [network] response to hydrogen peroxide  (80 genes)  ISO ISS  
GO:0000187 [list] [network] activation of MAPK activity  (83 genes)  ISO ISS  
GO:0007626 [list] [network] locomotory behavior  (106 genes)  ISO ISS  
GO:0031667 [list] [network] response to nutrient levels  (120 genes)  IDA IEP  
GO:0006979 [list] [network] response to oxidative stress  (143 genes)  IMP ISO TAS  
GO:0007605 [list] [network] sensory perception of sound  (143 genes)  ISO ISS  
GO:0010033 [list] [network] response to organic substance  (153 genes)  ISO ISS  
GO:0043524 [list] [network] negative regulation of neuron apoptotic process  (163 genes)  ISO ISS  
GO:0045471 [list] [network] response to ethanol  (197 genes)  ISO ISS  
GO:0007568 [list] [network] aging  (319 genes)  ISO  
GO:0007283 [list] [network] spermatogenesis  (379 genes)  ISO ISS  
GO:0042493 [list] [network] response to drug  (523 genes)  ISO ISS  
GO:0043066 [list] [network] negative regulation of apoptotic process  (531 genes)  IMP ISO  
GO:0055114 [list] [network] oxidation-reduction process  (616 genes)  IEA  
GO CC
GO:0031045 [list] [network] dense core granule  (16 genes)  IDA  
GO:0032839 [list] [network] dendrite cytoplasm  (26 genes)  ISO ISS  
GO:1904115 [list] [network] axon cytoplasm  (41 genes)  IEA  
GO:0005758 [list] [network] mitochondrial intermembrane space  (73 genes)  IDA  
GO:0005777 [list] [network] peroxisome  (125 genes)  IDA ISO  
GO:0030141 [list] [network] secretory granule  (126 genes)  IDA  
GO:0043209 [list] [network] myelin sheath  (191 genes)  IEA ISO  
GO:0005764 [list] [network] lysosome  (263 genes)  IDA  
GO:0031410 [list] [network] cytoplasmic vesicle  (281 genes)  ISO ISS  
GO:0031012 [list] [network] extracellular matrix  (326 genes)  ISO ISS  
GO:0043005 [list] [network] neuron projection  (398 genes)  IDA  
GO:0043025 [list] [network] neuronal cell body  (570 genes)  IDA ISO ISS  
GO:0005576 [list] [network] extracellular region  (756 genes)  IDA  
GO:0043234 [list] [network] protein-containing complex  (760 genes)  IDA ISO ISS  
GO:0005615 [list] [network] extracellular space  (1394 genes)  IBA ISO ISS  
GO:0005739 [list] [network] mitochondrion  (1618 genes)  IDA ISO ISS  
GO:0005654 [list] [network] nucleoplasm  (1897 genes)  IEA ISO  
GO:0070062 [list] [network] extracellular exosome  (2641 genes)  IEA ISO  
GO:0005829 [list] [network] cytosol  (3046 genes)  ISO ISS  
GO:0005886 [list] [network] plasma membrane  (4100 genes)  ISO ISS  
GO:0005737 [list] [network] cytoplasm  (4459 genes)  IDA ISO ISS  
GO:0005634 [list] [network] nucleus  (4802 genes)  IDA ISO ISS  
GO MF
GO:0004784 [list] [network] superoxide dismutase activity  (5 genes)  IDA IMP ISO ISS  
GO:0030346 [list] [network] protein phosphatase 2B binding  (9 genes)  IDA ISO ISS  
GO:0048365 [list] [network] Rac GTPase binding  (48 genes)  IEA ISO  
GO:0005507 [list] [network] copper ion binding  (56 genes)  IMP ISO ISS TAS  
GO:0051087 [list] [network] chaperone binding  (86 genes)  ISO ISS  
GO:0019899 [list] [network] enzyme binding  (410 genes)  IPI  
GO:0008270 [list] [network] zinc ion binding  (696 genes)  IBA ISO ISS  
GO:0042802 [list] [network] identical protein binding  (1133 genes)  IEA ISO  
KEGG rno04146 Peroxisome
rno04213 Longevity regulating pathway - multiple species
rno05014 Amyotrophic lateral sclerosis (ALS)
rno05016 Huntington's disease
rno05020 Prion diseases
Orthologous [Ortholog page] SOD1 (hsa)Sod1 (mmu)sod1 (dre)Sod3 (dme)Sod1 (dme)sod-5 (cel)sod-1 (cel)sod-4 (cel)T01D3.3 (cel)SOD1 (gga)SOD1 (cfa)SOD1 (mcc)LOC693966 (mcc)SOD1 (sce)sod1 (spo)CG45546 (dme)
Subcellular
localization
cyto 8,  cyto_nucl 5,  nucl 1  (predict for NP_058746.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04146 Peroxisome 3
rno01212 Fatty acid metabolism 2
rno00480 Glutathione metabolism 2
rno00980 Metabolism of xenobiotics by cytochrome P450 2
rno05204 Chemical carcinogenesis 2
Genes directly connected with Sod1 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
258.5 Prdx1 peroxiredoxin 1 [detail] 117254
792.9 Hint2 histidine triad nucleotide binding protein 2 [detail] 313491
803.5 Tmem205 transmembrane protein 205 [detail] 300441
925.6 Pecr peroxisomal trans-2-enoyl-CoA reductase [detail] 113956
933.1 Sccpdh saccharopine dehydrogenase (putative) [detail] 305021
Coexpressed
gene list
[Coexpressed gene list for Sod1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 24786    
Refseq ID (protein) NP_058746.1 


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