[][] mmu Top2b Gene 
functional annotation
Function   topoisomerase (DNA) II beta
GO BP
GO:0044774 [list] [network] mitotic DNA integrity checkpoint  (2 genes)  IBA  
GO:0000819 [list] [network] sister chromatid segregation  (3 genes)  IBA  
GO:2001034 [list] [network] positive regulation of double-strand break repair via nonhomologous end joining  (5 genes)  ISO  
GO:0006265 [list] [network] DNA topological change  (7 genes)  ISO  
GO:0071318 [list] [network] cellular response to ATP  (10 genes)  ISO  
GO:0000712 [list] [network] resolution of meiotic recombination intermediates  (13 genes)  IBA  
GO:0006259 [list] [network] DNA metabolic process  (19 genes)  IEA  
GO:0070301 [list] [network] cellular response to hydrogen peroxide  (43 genes)  ISO  
GO:0030900 [list] [network] forebrain development  (75 genes)  IMP  
GO:0007569 [list] [network] cell aging  (80 genes)  ISO  
GO:0007409 [list] [network] axonogenesis  (102 genes)  IMP  
GO:0001764 [list] [network] neuron migration  (117 genes)  IMP  
GO CC
GO:0000792 [list] [network] heterochromatin  (31 genes)  ISO  
GO:0005694 [list] [network] chromosome  (371 genes)  IDA  
GO:0005730 [list] [network] nucleolus  (710 genes)  ISO  
GO:0005654 [list] [network] nucleoplasm  (1912 genes)  ISO  
GO:0005829 [list] [network] cytosol  (2800 genes)  ISO  
GO:0005634 [list] [network] nucleus  (5524 genes)  IDA ISO  
GO MF
GO:0003918 [list] [network] DNA topoisomerase type II (ATP-hydrolyzing) activity  (3 genes)  ISO  
GO:0003916 [list] [network] DNA topoisomerase activity  (6 genes)  IEA  
GO:0043021 [list] [network] ribonucleoprotein complex binding  (41 genes)  ISO  
GO:0005080 [list] [network] protein kinase C binding  (56 genes)  ISO  
GO:0042826 [list] [network] histone deacetylase binding  (105 genes)  ISO  
GO:0016853 [list] [network] isomerase activity  (116 genes)  IEA  
GO:0008022 [list] [network] protein C-terminus binding  (228 genes)  ISO  
GO:0019899 [list] [network] enzyme binding  (389 genes)  ISO  
GO:0003682 [list] [network] chromatin binding  (444 genes)  ISO  
GO:0046982 [list] [network] protein heterodimerization activity  (539 genes)  ISO  
GO:0005524 [list] [network] ATP binding  (1368 genes)  IEA  
GO:0000166 [list] [network] nucleotide binding  (1666 genes)  IEA  
GO:0003677 [list] [network] DNA binding  (1709 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (2999 genes)  IEA  
GO:0005515 [list] [network] protein binding  (4163 genes)  IPI  
KEGG mmu01524 Platinum drug resistance
Orthologous [Ortholog page] TOP2A (hsa)TOP2B (hsa)Top2a (mmu)Top2 (dme)top-2 (cel)cin-4 (cel)R05D3.12 (cel)top2a (dre)Top2a (rno)Top2b (rno)TOP2A (gga)TOP2B (gga)TOP2B (cfa)TOP2A (cfa)top2b (dre)TOP2B (mcc)TOP2A (mcc)TOP2 (sce)top2 (spo)
Subcellular
localization
cyto_nucl 5,  cyto 4,  nucl 4  (predict for NP_033435.2)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04120 Ubiquitin mediated proteolysis 3
mmu04110 Cell cycle 3
mmu05166 HTLV-I infection 2
mmu01524 Platinum drug resistance 2
Genes directly connected with Top2b on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
176.7 Arid4b AT rich interactive domain 4B (RBP1-like) [detail] 94246
276.1 Stag2 stromal antigen 2 [detail] 20843
327.9 Atrx ATRX, chromatin remodeler [detail] 22589
357.5 Fmr1 fragile X mental retardation syndrome 1 [detail] 14265
446.5 Ralgapa1 Ral GTPase activating protein, alpha subunit 1 [detail] 56784
468.1 Ints8 integrator complex subunit 8 [detail] 72656
680.5 Pibf1 progesterone immunomodulatory binding factor 1 [detail] 52023
Coexpressed
gene list
[Coexpressed gene list for Top2b]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 21974    
Refseq ID (protein) NP_033435.2 


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